Digestive, Reproductive, and Urinary Disorders Flashcards
Common manifestations of disorders
Anorexia, nausea, and vomiting
Emesis definition
forceful expulsion of chyme (food and digestive juices) from the stomach
Signs and symptoms of emesis
often associated with increase salivation, pallor, and sweating. May be preceded by retching/dry heaves
Hematemesis
presence of blood in vomit
coffee-grounds
old brown, partially digested blood
frank blood
obvious blood; large amount, new (red) hemorrhage
yellow or green vomit
bile from duodenum
Treatment for emesis
Zorfran (anti emetic) and fluids
Cause of diarrhea Large Volume
secretory or osmotic diarrhea related to infection, short transit time, lactose intolerance
Cause of small volume diarrhea
associated with inflammatory bowel disease, stool may contain blood/mucus/pus, and may be accompanied by abdominal cramps
Steatorrhea cause
fatty particles associated with malabsorption syndromes, frequent bulky greasy loose stools. A lot of CF patients have this
Constipation Acute cause
inadequate dietary fiber, inadequate fluid intake, failure to respond to defecation reflex, muscle weakness/inactivity, drugs that slow peristalsis, mechanical obstruction
What types of drugs that slow peristalsis
opiates (morphine), anticholinergics
Chronic constipation cause
hemorrhoids, diverticulitis and severe constipation
Cause of fluid and electrolyte imbalance
loss of fluid via vomiting and diarrhea, ions lost with fluid, acid-base imbalance due to lost hydrochloric acid and bicarb
Main forms of fluid and electrolyte cause
dehydration, overhydration ( rare and not usually a problem for normal kidney), water intake must balance water loss, drinking too much is usually better than too little,
Water is absorbed primarily by what?
digestive tract
during dehydration water is lost by what?
kidney excretion depending on bodys needs
During evaporation water is lost how?
through the skin and exhalation of the lungs, profuse sweating, exercise, fever, hot weather, loss of fluid via vomiting and diarrhea
Signs and Symptoms of dehydration
thrist, dry sticky mouth, dizziness/tiredness, dec.urine output, dry skin, rapid heartbeat and breathing
Treatment for dehydration
drink more water, electrolyte and carbohydrate rich solutions, dec.sodium intake, and avoid caffeinated beverages
Cleft lip/palate
developmental abnormality of mouth and face, arises in 2nd or 3rd month of gestation and be inherited/enviromental
Cleft lip cause
failure to fuse in weeks 4-8 of fetal development. Can be unilateral or bilateral
Cleft palate cause
failure of hard and soft palates to fuse, opening between oral and nasal cavities, causing feeding problems in infants
Treatment for cleft palate and cleft lip
surgical repair, speech therapy, orthodontia
Oral Candidiasis
Thrush, candida albicans in normal oral flora, opportunistic infection.
Symptoms of thrush
red swollen patches on oral mucosa, makes eating and drinking painful
How to treat with thrush
topical antifungal agent (Nystatin, Mycostatin)
Dysphagia
difficulty swallowing
Cause of dysphagia
neurologic deficit with cranial nerves (V, VII, IX, X, XII), brain damage, achalais (failure to lower/open esophageal sphincter)
Muscular disorders
muscular dystrophy, ALS
Mechanical obstruction that cause dysphagia
congenital atresia, stenosis, esophageal diverticula, and tumors
Gastro Esophageal Reflux Disease (GERD) cause
At the lower end of the esophagus, where it joins the stomach, there is a circular ring of muscles called the lower esophageal sphincter, after swallowing the LES relaxes and allows food to enter stomach and then contracts to prevent food back up. The LES becomes weak or relaxed when the stomach is distended, which allows liquids in the stomach to go back into esophagus
Acid Reflux becomes GERD when?
it causes bothersome symptoms or injury to esophagus
Signs and symptoms of GERD
stomach pain, non-burning chest pain, difficulty swallowing, painful swallowing, persistent laryngitis/hoarseness, persisten laryngitis/hoarseness, persistant sore throat, chronic cough, new onset asthma, or asthma wheeze only at night
Acid reflux complications
ulcers, stricture, lung and throat problems, esophageal cancer, Barretts esophagus
Barretts esophagus is what?
esphageal cells are replaced with intestinal cells due to repeated acid exposure
Diagnostic tests of GERD
endoscopy, 24 hour esophageal pH study, esophageal manometry (involves swallowing a tube that measures the muscle contractions of the esophagus)
Treatment for GERD
weight loss, head of bed raised 6=8 inches, avoid acid reflux inducing foods, avoid large and late meals, proton pump inhibitors, histamine H-2 blockers, surgery
Hiatal Hernia cause
protrusion of a portion of stomach through esophageal hiatus into thoracic cavity
Sliding hernia most common slides up when?
when the person is supine, it returns to normal when standing
Paraesophageal hernia more likely to ulcerate due to what?
compressed vessels
Chronic esophagitis may cause what?
fibrosis and stricture
Symptoms of a hernia
seen in conjunction with GERD, heart burn, sour taste in mouth, increased discomfort when lying down or bending over
Treatment of a hernia
frequent small meals, avoid lying down after meals, avoid restrictive clothing around waist, elevate head of bed, antacids, if severe surgery
Gastroenteritis cause
usually due to infection (e coli, salmonella, contaminated food/water), may be allergic reaction to foods or drugs, inflammation of stomach (vomiting), inflammation of intestines (diarrhea)
E coli
some strains extremely virulent, present in cows, release toxins that damage intestinal mucosa and blood vessels, can cause bloody diarrhea and acute renal failure, may cause death in kids, elderly or those with low immunity
Treatment of a gastroenteritis
usually self limiting, provide adequate fluids and electrolytes, antibiotics in persistent/severe cases of E. coli
Prevention of gastroenteritis
hand washing, properly cook food
Peptic ulcers (PUD) found where?
most common in proximal duodenum, also found in antrum of stomach and lower esophagus, genetic predisposition is questioned
Peptic ulcers are more common in who?
men, elderly, type O blood
peptic ulcers are caused by?
increased acid pepsin secretion, breakdown of gastric mucosal barrier
Precipitating factors of peptic ulcers
inc. acid pepsin secretion due to ingestion of alcohol, NSAIDS, ceffeine, certain foods and abnormal feedback mechanism, breakdown of mucosal barrier due to heliobacter pylori, inadequate blood supply, excessive glococorticoids, ulcerogenic substances
Heliobacter pylori
present in 50% of people; most have no complications
Complications of peptic ulcers
bleeding, perforation, obstruction
Treatment of peptic ulcers
difficult to heal due to stomach acids irritates lesions, antibiotics, meds to reduce acid secretion, remove exacerbating factors
Cholelithiasis
formation of gallstones
Cholecystitis
inflammation of the gallbladder and cystic ducts
Cholangitis
inflammation of bile ducts due to infection
Cause of gallbladder disorders related to gallstones
inflammation in biliary structures may provide focus for stone formation, stones initially form in bile ducts, gallbladder, cystic duct
Cholesterol gallstones are more common in who?
women especially associated with obesity, inc. cholesterol intake, giving birth multiple times, oral contraceptives/estrogen supplements
Bile pigment stones associated with what?
hemolytic anemia, alcoholic cirrhosis, biliary tract infections
Signs and symptoms of gallbladder disorders
frequently asymptomatic, if large stone obstructs duct may become biliary colic, pain in upper right quadrant, pain often radiates to back and right shoulder, nausea/vomiting, fever and leukocytosis
Treatment of gallbladder
surgical removal via laproscopic cholecystectomy, long term medication use to dissolve stones
Hepatitis A
transmission via oral fecal route, 2-6 week incubation period, fecal shedding of virus weeks before onset of signs, acute, self-limiting infection (not chronic/ not carriers)
Hepatitis B
transmission via blood and body fluids, 1-6 month incubation period, may be asymptomatic carrier or develop acute infection
Hepatitis C
originally referred to as non A non B, proven existence in 1989, transmitted via blood and body fluids, 2-6 week incubation period, may be carrier or develop chronic infection
Hepatitis D
requires presence of Hep B for replication, increase severity of Hep B infection
Hepatitis E
similar to Hep A, oral fecal transmission, 2-9 week incubation, no carrier/chronic state
Researchers questions the existence of hepatitis what?
F and G
Signs and symptoms of Hepatitis
preicteric stage- general systemic signs of infection, mild upper right quadrant discomfort, elevated liver enzymes in serum. Icteric stage- jaundice, dark urine, hepatomegaly with tenderness, may be prolonged clotting times. Posticteric stage- slow recovery
Treatment of Hepatitis
supportive measures, anti viral drugs
Cirrhosis cause
the 3 general causes are alcoholic liver disease (most common), biliary cirrhosis due to obstructed bile flow, postnecrotic cirrhosis (due to chronic hepatitis or long term exposure to toxic agents)
Signs and Symptoms of cirrhosis
ascites (fluid in peritoneal cavity), generalized edema, esophageal varices (due to portal hypertension), anemia and increased bleeding, jaundice, and hepatic encephaolopathy
Treatment of Cirrhosis
supportive measures, emergency treatment of reptured esophageal varcies, portocaval shunt, liver transplant, make end life decisions
Acute pancreatitis causes
alcohol abuse, gallstones, viral infection, drug reaction
Signs and symptoms of acute pancreatitis
severe epigastric and abdominal pain that radiates to back, shock, fever, abdominal distention, and decreased bowel sounds
Treatment of acute pancreatitis
20% mortality rate, nothing by mouth/orally, analgesics (not morphine), treat shock and electrolyte imbalance, monitor all other vitals
Structural abnormalities in female reproductive system
changes in uterine position
Normal anatomical position in females
Antevered (tipped forward) Anteflexed (bent foward over bladder)
Retroversion
tipped backward (1st-3rd degree) could compress colon
Retroflexion
Bent back towards rectum, could also impress colon
Anteflexion
bent forward toward bladder
cause of positional abnormalities in female reproductive system
congenital anatomic variation, childbirth, pathologic conditions (scar tissue/tumor)
Supporting structures for uterus, bladder, rectum become weakened due to?
multiple/difficult childbirths, trauma, aging, effects appear from menopause
Signs and symptoms of positional abnormalities in females?
often asymptomatic, may be infertile due to poor positioning of the cervix.
Symptoms associated with 3rd degree retroversion
back pain, dysmenorrhea (heavy/difficult menstration), dyspareuma (painful intercourse)
Prevention of positional abnormalities in females
kegel exercises