Digestive Flashcards
Which enzyme acts on triglycerides and where?
lingual lipase; activated in the stomach
Which enzyme acts on starches (carbs) and where?
salivary amylase; activated in saliva
Which enzyme lyses bacteria?
bacterial lysozome
Immunoglobulin A
secreted antibody that prevents attachment of microbes so that they cannot penetrate epithelium
What initial step leads to digestion of protein?
activation of pepsinogen into pepsin by HCl
The mucosa of the stomach is made up of
simple columnar epithelium (suface mucous cells), lamina propia and muscularis mucosae
Food is reduced to chyme how?
contraction of the muscularis - macerates food, mixes with gastric juices
The gastric glands of the stomach are made up of
epithelium
Parietal cells within gastric glands
secrete HCl, which activates pepsinogen, protein denaturing, secretion of hormones that promote flow of bile, kills microbes in food. also secrete intrinsic factor to absorb vitamin b12 in the distal ilium
What stimulates the parietal cells to release HCl?
acetylcholine, gastrin, histamine
What inhibits Hcl?
somatostatin, prostaglandins, cholecytokinin
Vitamin b12 functions
coenzyme in AA metabolism, stimulates erithropoiesis, folate metabolism (RBC formation, cell growth & division)
Low B12 symptoms
anemia, poor memory, GI symptoms, fatigue, depression, weakness, ataxia
What enzyme digests carbohydrates in the small intestine?
pancreatic enzyme
tri/disaccharies are further broken down in the small intestine by
brush border enzymes