Digestive Flashcards

1
Q

Which enzyme acts on triglycerides and where?

A

lingual lipase; activated in the stomach

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2
Q

Which enzyme acts on starches (carbs) and where?

A

salivary amylase; activated in saliva

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3
Q

Which enzyme lyses bacteria?

A

bacterial lysozome

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4
Q

Immunoglobulin A

A

secreted antibody that prevents attachment of microbes so that they cannot penetrate epithelium

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5
Q

What initial step leads to digestion of protein?

A

activation of pepsinogen into pepsin by HCl

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6
Q

The mucosa of the stomach is made up of

A

simple columnar epithelium (suface mucous cells), lamina propia and muscularis mucosae

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7
Q

Food is reduced to chyme how?

A

contraction of the muscularis - macerates food, mixes with gastric juices

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8
Q

The gastric glands of the stomach are made up of

A

epithelium

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9
Q

Parietal cells within gastric glands

A

secrete HCl, which activates pepsinogen, protein denaturing, secretion of hormones that promote flow of bile, kills microbes in food. also secrete intrinsic factor to absorb vitamin b12 in the distal ilium

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10
Q

What stimulates the parietal cells to release HCl?

A

acetylcholine, gastrin, histamine

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11
Q

What inhibits Hcl?

A

somatostatin, prostaglandins, cholecytokinin

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12
Q

Vitamin b12 functions

A

coenzyme in AA metabolism, stimulates erithropoiesis, folate metabolism (RBC formation, cell growth & division)

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13
Q

Low B12 symptoms

A

anemia, poor memory, GI symptoms, fatigue, depression, weakness, ataxia

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14
Q

What enzyme digests carbohydrates in the small intestine?

A

pancreatic enzyme

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15
Q

tri/disaccharies are further broken down in the small intestine by

A

brush border enzymes

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16
Q

glucose, galactose and fructose are

A

monosaccharides

17
Q

What kinds of carbohydrates are absorbed in the small intestine?

A

only monosaccharides

18
Q

Fructose is absorbed in the lumenal membrane via

A

facilitated diffusion

19
Q

glucose/galactose are absorbed in the lumenal membrane via

A

secondary active transport with Na+

20
Q

In the basolateral membrane, how do monosaccharides cross?

A

facilitated diffusion for all (fructose, galactose, and glucose)

21
Q

Where do monosaccharides go after crossing the basolateral membrane?

A

capillary of the villus

22
Q

pancreatic juice in the small intestine digests proteins. What is it made up of?

A

trypsin, chymotrypsin, carboxypeptidase, elastase

23
Q

What digests proteins in the stomach?

A

pepsin - breaks it down into di/tripeptides

24
Q

In the small intestin, what breaks down proteins?

A

brush border enzymes ( aminopeptidase, fatty acids )