Digestion- Biochem Exam 1 Flashcards
Food + Saliva
Bolus
Bolus is moved through GI by
Peristalsis
Peristalsis is stimulated by
Distention
Law of the Gut
Irritation
Parasympathetic Nerves
Peristalsis is inhibited by
Sympathetic Nerves
Chewing ___ surface area
increases
Digestion in the Mouth
Carbs & Lipids
Top and bottom parts of esophagus
top: esophageal sphincter
bottom: gastroesophageal sphincter
Part of esophagus that causes reflux
gastroesophageal sphincter
Stages of swallowing in esophagus
1 Pharyngeal Phase
2 Esophageal Phase
Pharyngeal Phase
Folds pulled medially to form a slit, preventing large food from entering
Esophageal Phase
Moving food through for peristalsis
Parts of the stomach
Cardia
Fundus
Body
Antrum
Cardia
Walmart greeter
Fundus
gas collector
Body
gastric juices
Antrum
Peristalsis
Stomach is connected to SI by
Pyloric Sphincter
Stomach Cells
Neck
Chief
Parietal
Enteroendocrine
Neck Cells
mucus and bicarbonate
Chief Cells
Enzymes
Parietal Cells
HCl and intrinsic factor
Required for B12 and digest/kill off protein
*are stimulated by gastrin
Enteroendocrine Cells
Hormones
Secrete G cells (gastric)
Digestion in Stomach
Lipids
Proteins
Gastric Juice + Bolus
Chyme
Liver receives blood from
Portal Vein
Storage in liver
Iron
B12
Vitamin A
Vitamin D
Metabolic Function of Liver- Carbs
- gluconeogenesis
- storage of glucose
- turning sugars to glucose
Metabolic Functions of Liver- Lipids
- Oxidation of fatty acids
- Synthesis of Triglyceride, Lipoproteins, cholesterol, bile, phospholipids
Metabolic Function of Liver- Protein
- Plasma Proteins
- Formation of urea
- Amino acid inter conversion
Detoxification in Liver
Phase I: cytochrome P450
Phase 2
Cells in pancreas
Endocrine cells
Exocrine cells
Endocrine Cells
Insulin
Glucagon
(hormones)
Exocrine Cells
Bicarbonate
Digestive enzymes
Digestion in SI by Pancreatic Enzymes
Carbs
Lipids
Proteins
Secretion of Gallbladder with CCK
Bile
Function of bile in gallbladder
increase surface area of lipids
Motilin increased motility in
Stomach
SI
LI
When is Motilin secreted
fasted state
Parts of Small Intestine
Duodenum
Jejunum
Ileum
Duodenum
Most digestion occurs
Secretes bile
Jejunum
Most absorption occurs
Layers of Small Intestine
Mucosa
Submucosa
Muscularis Externa
Serosa
Mucosa
Makes secretions – Brush Border enzymes
Brush Border enzymes digestion in SI
Carbs
Proteins
*In mucosa of SI
Submucosa
controls secretions in submucosal plexus
Muscularis Externa
Peristalsis occurs in Myenteric Plexus
Serosa
Protection
Enteric Nervous System
Inhibitory and Stimulatory Neurotransmitters
Inhibitory Neurotransmitter
Norepinerphine
Stimulatory Neurotransmitter
Acetylcholine – causes contraction
Water is absorbed in
Large Intestine
Fermented products in LI
Gas
Short-chained fatty acids
Decreases gastric motility
Secretin
CCK
GIP
Gastrin stimulated by Parietal Cells of Stomach
Increases motility
CCK in Pancreas and Gallbladder
stimulates bicarbonate secretion in exocrine cells of pancreas
stimulates secretion of everything in gallbladder (*Only hormone to that causes gallbladder to secrete bile)
GIP in Pancreas
Stimulates secretion of insulin in endocrine cells
regulates blood glucose
Secretin in Pancreas
Stimulates bicarbonate secretions
opposes action of gastrin
Hunger
Physiological need to eat
Satiety
Feeling of fullness
Appetite
Psychological want to eat