Digestion and absorption AAU Flashcards
Digestion of various food is by the process of
hydrolysis
Digestion is?
different types of food are broken in the absorbable units “ principally in the small intestine.
Absorption is ?
the products of digestion and vitamins, minerals and water crosses mucosa and enter the blood or lymph
Carbohydrate Digestion the mouth ?
Salivary α amylase acts on polysaccharides
starches is hydrolyzed into maltose
not more than 5 %of all the starches will have become hydrolyzed
Carbohydrate Digestion In the stomach ?
Salivary α amylase is essentially nonactive once the pH below 4.0.
Carbohydrate Digestion In the intestine?
Pancreatic α amylase
the carbohydrates are almost totally converted into maltose and/or other very small glucose polymers before passing beyond the duodenum or upper jejunum.
Products of starch digestion by α amylase ?(3)
- Disaccharides: maltose.
- Trisaccharides: maltotriose.
- Short polymesr: α dextrins.
enzymes found in the brush border ?(5)
- α dextrinase
- Maltase
- Sucrase
- Lactase
- Trehalase
α dextrinase:
Acts on alpha dextrins, maltose & maltotroise. α dixtrinase also known as isomaltase it hydrolyses 1:6α linkages. along with maltase and sucrase it also breaks down maltotriose and maltose.
Maltase?
Acts on maltose to give glucose -glucose
Sucrase ?
Acts on sucrose to give glucose =fructose
Lactase?
Acts on lactose give glucose + galactose.
Trehalase:
Acts on trehalose to give glucose+glucose
The absorbed units of carbs enter
portal circulation portal vein.
Glucose absorption On luminal membrane
Accomplished by carries for co-transport to inside the cell
Sodium –glucose transports 1 & 2 (SGLT1 & SGLT2).
Glucose absorption On basolateral membrane?
(carriers for facilitated diffusion to the ISF). Glucose transporters 1 & 2 (GLUT1 & GLUT2).
The Glucose transporter sensitive to insulin
GLUT-4
found in fat & muscle cells
Galactose Absorption?
Similar to glucose (i.e.co transported with sodium “secondary active transport”).
Fructose Absorption by
Facilitated diffusion that is Independent of Na
Fructose Absorption To enterocytes by
GLUT5