Digestion Flashcards

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1
Q

Name the three enzymes and what they digest

A

Carbohydrases - hydrolyse carbohydrates to monosaccharides

Lipases - hydrolyse lipids (fats and oils) into glycerol and fatty acids

Proteases - hydrolyse proteins to amino acids

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2
Q

Define Digestion

A

Digestion is the process in which large (insoluble) molecules are hydrolysed by enzymes into small, soluble molecules, which can be absorbed and assimilated.

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3
Q

Absorption

A

Soluble molecules are taken into the blood stream through the intestinal lining

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4
Q

Explain what role the mouth has in the digestive system

A

The mouth contains teeth which break down food into smaller pieces and increases the surface area to volume ratio. Carbohydrates digestion begins here

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5
Q

Explain the role of the structure Oesophagus

A

A hallow tube with muscular walls through which food passes from the mouth to the stomach.

Contractions of the smooth muscles in the wall of the oesophagus help move food down towards the stomach

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6
Q

Explain the role the stomach has in the digestive system

A

Protein digestion begins here
Glandular tissue produces enzymes and stomach acid
Muscular tissue churns food miking it with enzymes and acid
the acids help to unravel the proteins to enable enzymes activity, as well as lowering ph which is optimal for stomach enzymes to work

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7
Q

Explain the role of the llumen in digestion (end of small intestine)

A

Long and lined with microvilli to increase the surface area over which asportion can take place

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8
Q

Explain the role of the large intestine in digestion

A

any water remaining that was not able to be digested such as cellulose found in plant fiber, is absorbed here

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9
Q

Explain the role of the rectum in the digestive system

A

Undigested food materials in the rectulm and removed through the anus

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10
Q

Explain the role of the salivary glands in the digestive system

A

produces digestive juices- anyalse

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11
Q

Explain the roles of the pancreas in the digestive system

A

Produces digestive juices

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12
Q

Digestion of starch

A

Starch (long and branched) -analyse a digestive enzyme breaks down starch to maltose (prdouced in the salivary glands and dudenium)- disaccharide- maltase (dudodium and illumen-inside of the cell of gut muscua) in the small intestine breaks down maltose to glucose - monosaccride (glucose)

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13
Q

describe digestion of carbohydrates by amylases and membrane-bound disaccharidases in mammals?

A

Mouth
Mastication
Salivary amylase
Starch hydrolysed to maltose

Stomach
Acidic pH denatures amylase

Small intestine (duodenum - ileum)
Pancreatic amylase continues starch hydrolysis / neutral pH
Peristalsis
Maltase hydrolyses maltose to glucose
Maltase is a membrane-bound disaccharidase

PLUS
Sucrase
Lactase

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14
Q

Structural features of ilumen

A

Cell surface membrane is heavily folded with microvilli to greatly increase the surface area for transport.

Many protein transport channels / carrier proteins to increase the rate of absorption.

Large numbers of mitochondria to produce ATP via aerobic respiration for active transport / cotransport.

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15
Q

Explain the co transport of glucose

A

Sodium ions are being actively pumped out of the cuboidal cells by active, ATP driven Na / K exchange pumps.

This sets up a sodium ion concentration gradient., with a higher concentration of sodium ions on the outside.

The co-transporter then facilitates the sodium ions diffusing in down their gradient to “pull in” glucose molecules into the cytoplasm against its gradient (maximum absorption).

The glucose can then passively diffuse out through other carrier proteins onto the other side / passing into the blood capillaries.

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16
Q

Digestion of proteins/polypeptides

A

PROTIEN
Endopeptidase e.g. pepsin (gastric glands)
Shorter polypeptide (more ends)
Exopeoptidase (remove terminal amino acids)
DIPEPTIDES
Dipeptidase (duodenum and ileum-inside cells of gut mucosa
AMINO ACID (small soluble)

Endopeptidases (stomach) produce multiple shorter polypeptides which allows more exopeptidases (pancreatic) to hydrolyse more terminal peptide bonds, releasing amino acids faster.

Dipeptidases (membrane bound - ileum) release further amino acids.

17
Q

Digestion of Lipids

A

Lipids
Bile salts
Emulsified Lipids
Lipase (dudomeum and illuem)
Fatty acids and glycerol

Bile salts which have a hydrophilic side and a hydrophobic side secreted from the liver (also gallbladder) emulsify lipid (fat) globules. This increases the surface area for pancreatic lipase to hydrolyse the triglyceride molecules into glycerol and fatty acids

18
Q

Describes the absorption of lipids

A

Dissolved fatty acids enter the epithelial cells by diffusion. Triglycerides are reformed by the ER or Golgi apparatus. Formation of a chylomicron when fatty acid combines with protein. Chylomicron released by exocytyosis as to large and pass to lymphatic vessels and then the bloodstream via the lacteal