DIGESTION Flashcards

1
Q

Alimentary canal

A

continuous tube from the mouth to anus

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2
Q

Examples of accessory digestive organs

A

mouth, pancreas, liver, gallbladder

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3
Q

What do the pancreas, liver, and gallbladder do?

A

secrete enzymes in the system

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4
Q

The function of the Gastrointestinal tract do?

A

Convey food along GIT, allowing it to be broken down into small molecules which can be absorbed into the circulation

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5
Q

Purpose of secretion

A

chemical breakdown by glandular activity - exocrine and endocrine

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6
Q

Purpose of motility

A

propulsion and physical breakdown - muscular activity

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7
Q

Purpose of absorption

A

transfer to blood circulation

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8
Q

GITs role

A

provide nutrients to the body

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9
Q

Digestive and Absorptive capacity of GIT

A

The GIT is efficent
Carbs = 99%
Fat = 95%
Protein = 92%

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10
Q

GIT structure

A

Tubular Nature

Communication with External Environment at Both Ends

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11
Q

Size of GIT compared to human

A

4.5 m vs 1.5 m

GIT Length is way larger

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12
Q

Internal vs external GIT surface area

A

600x larger internal surface area

200-250 m^2

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13
Q

Four functional layers of the GI tract (inside to outside)

A

mucosa, submucosa, muscularis externa, serosa

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14
Q

Serosa

A

Thin, tough layer of connective tissue

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15
Q

Muscularis Externa

A

two layers of muscle (longitudinal and circular fibres)

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16
Q

Muscularis Externa muscle types

A

Mouth to Esophagus - striated muscle type
Esophagus to Anus - smooth muscle type
Anus - striated muscle type

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17
Q

Submucosa

A

Loose connective tissue containing lymphatics and blood vessels

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18
Q

Mucosa layers (outside to inside)

A

Muscularis mucosae, Lamina propria, Epithelial layer

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19
Q

Muscularis mucosae

A

smooth muscle

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20
Q

Lamina propria

A

loose connective tissue

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21
Q

Epithelial layer

A

epithelial and glandular cells play a role in the absorption

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22
Q

Longitudinal fibres

A

outer layer, when it contracts, GIT shortens

23
Q

Circular fibres

A

inner layer, when it contracts, lumen narrows

24
Q

Where is Muscularis Externa in striated?

A

oral cavity, pharynx, upper 1/3 esophagus and external anal sphincter

25
Where is Muscularis Externa in smooth?
rest of the GIT
26
Plexus
collection of nerve cell bodies
27
Two types of plexus
submucosal plexus, myenteric plexus
28
What do the plexus contain?
sensory neurons, motor/effector neurons
29
Purpose of Interneurons in the GIT
expand the responses to stimuli in the GIT
30
motor/effector neurons in the GIT
activate the secretory and muscle cells
31
Types of Enteric Neurons
excitatory, inhibitory
32
Excitatory enteric neurons release
ACh
33
Inhibitory enteric neurons release
NANC (NO)
34
What is Ach blocked by?
atropine
35
Non-adrenergic, non cholinergic
NANC
36
The ENS consists of the myenteric plexus between
longitudinal and circular muscle layers
37
The ENS consists of ganglion cells and their processes which synapse with
smooth muscle cells, endocrine and exocrine cells, and other ganglion cells
38
Enteric sensory fibers get information from
gut chemoreceptors and mechanoreceptors
39
Parasympathetic ganglions
preganglionic
40
Sympathetic ganglions
postganglionic
41
Where does the parasympathetic system innervate from?
vagus X, pelvic nerves
42
Where does the sympathetic system innervate from?
celiac, superior mesenteric, inferior mesenteric ganglion
43
How does ANS influence the GIT
through the ENS
44
Parasympathetic input on blood vessels
dilation of blood vessels
45
Sympathetic input on blood vessels
constriction of blood vessels
46
Parasympathetic affect on ENS
neurons reach the wall of the GIT as preganglionic fibers, synapsing (via nicotinic ACh receptors) with enteric neurons (both excitatory and inhibitory) exerting an excitatory effect.
47
Sympathetic affect on ENS
neurons reach the wall of the GIT as postganglionic fibers, synapsing (via NA receptors) with enteric neurons (both excitatory and inhibitory) exerting an inhibitory effect
48
Sympathetic neurons affect on smooth muscle in blood vessels
vasoconstriction
49
What allows for long reflexes
Sensory neurons
50
What does the ENS innervate (reflex)
independent, integrative innervation; regulates GIT via SHORT, INTRAMURAL REFLEXES
51
What does the ANS innervate (reflex)
“modulates” ENS activity via LONG, EXTRINSIC REFLEXES – synaptic connections with ENS neurons
52
What may influence the growth and development of GIT
Non-GIT hormones
53
What may influence outside the GIT
GIT hormones