Diffusion Flashcards
What is the alveolar surface area?
Around 50-100 m2
What is passive diffusion directly and inversely proportional to?
Directly: surface area
Inversely: thickness
What is the thickness of a alveolar capillary wall?
1 um or less
What is the main driving force of diffusion? Secondary forces?
- Pressure differences
- Molecular weight
- Solubility
Does CO2 or O2 dissolve better?
CO2 by 20x
What gases are limited by diffusion in the lungs?
CO
O2
What is the pressure of O2 in blood as it enters pulmonary capillaries?
40 mmHg O2
What is the pressure of O2 in the alveolar space?
100 mmHg O2
Under normal circumstances, how long does it take for O2 to diffuse across the alveolar capillary wall?
.25 seconds
What is diffusion capacity?
Vco/(P1-P2)
What is diffusion capacity usually equal to?
25 ml/min/mmHg
What gases are limited by perfusion in the lungs?
N2O, CO2, O2