Diffusion Flashcards

0
Q

What is the alveolar surface area?

A

Around 50-100 m2

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1
Q

What is passive diffusion directly and inversely proportional to?

A

Directly: surface area
Inversely: thickness

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2
Q

What is the thickness of a alveolar capillary wall?

A

1 um or less

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3
Q

What is the main driving force of diffusion? Secondary forces?

A
  1. Pressure differences
  2. Molecular weight
  3. Solubility
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4
Q

Does CO2 or O2 dissolve better?

A

CO2 by 20x

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5
Q

What gases are limited by diffusion in the lungs?

A

CO

O2

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6
Q

What is the pressure of O2 in blood as it enters pulmonary capillaries?

A

40 mmHg O2

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7
Q

What is the pressure of O2 in the alveolar space?

A

100 mmHg O2

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8
Q

Under normal circumstances, how long does it take for O2 to diffuse across the alveolar capillary wall?

A

.25 seconds

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9
Q

What is diffusion capacity?

A

Vco/(P1-P2)

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10
Q

What is diffusion capacity usually equal to?

A

25 ml/min/mmHg

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11
Q

What gases are limited by perfusion in the lungs?

A

N2O, CO2, O2

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