Diffuse Lung Disease Flashcards

1
Q

Smooth interlobular septal thickening

A
Acute:
- Cardiogenic edema
- Hemorrhage (ground glass opacity)
- Viral pneumonia (centrilobular nodule)
Chronic: 
- Lymphangitic carcinomatosis
- Amyloid
- Lymphoma
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2
Q

Acute interstitial pneumonia (ARDS)

- Diffuse, bilateral ggo with sparing of periphery due to alveolar damage

A
  • Trauma, high altitude, shock, drugs, neurological disease
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3
Q

Reverse halo sign

- Bilateral ggo and nodules internally with surrounding solid appearing ring

A
  • Organizing pneumonia
  • Fungal (paracoccidiomycosis)
  • Vasculitis (Churg-Strauss, Wegener’s)
  • Lymphoma
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4
Q

Chronic consolidation

A
  • Organizing pneumonia - occurs in response to lung injury
  • Eosinophilic pneumonia - upper lung predilection
  • Atypical infection (fungal pneumonia)
  • Sequestration
  • Adenocarcinoma spectrum
  • Lymphoma
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5
Q

Crazy paving

- Mid-lower lung predilection of ggo and smooth interlobular septal thickening

A
  • Alveolar proteinosis (accumulation of lipoprotein material in alveolar space)
  • Drug or hypersensitivity reactions
  • Non-cardiogenic edema
  • Pneumocystis infection
  • Other: hemorrhage, atypical infections, lipoid PNA, ARDS, BAC
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6
Q

Lipoid Pneumonia

- multiple fat density nodules/masses with Crazy paving (ggo and septal thickening)

A
  • Hamartoma
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7
Q

High density airspace opacities (80-175 HU)

A
  • Amiodarone deposition
  • Amyloidosis
  • Metastatic pulmonary calcifications
  • Talcosis
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8
Q

Calcified and enlarged mediastinal lymph nodes bilaterally with multiple nodules in an upper and middle lobe predominance

A
  • Sarcoidosis
  • Silicosis
  • Coal-worker pneumoconiosis
  • Lymphangitic carcinomatosis
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9
Q

Tiny ggo centrilobular nodules

A
  • Respiratory bronchiolitis (RB) - smokers disease
  • RB-ILD - smokers disease
  • Subacute hypersensitivity pneumonitis - non-smoker disease
  • Viral pneumonia
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10
Q

Innumerable, randomly distributed micronodules in upper and lower lungs bilaterally

A
  • Miliary infection (TB, histoplasmosis, fungus)
  • Hematogenous mets
  • Sarcoidosis
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11
Q

Honeycombing

A
  • Usual Interstitial Pneumonia (UIP)/IPF
    - honeycombing
    - septal thickening
    - architectural distortion
    - traction bronchiectasis
    - basal predominance
  • Asbestosis (pleural plaques)
  • RA (arthritis)
  • Chronic hypersensitivity
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12
Q

Upper lung honeycombing and fibrosis

A
  • End-stage sarcoidosis
  • Silicosis
  • Scarring from prior infection
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13
Q

Reticulation (interlobular and intralobular septal thickening)

A
  • Nonspecific Interstitial Fibrosis (NSIP)
    - reticulation
    - architectural distortion
    - traction bronchiectasis
    - basilar predominance
  • Collagen vascular disease (scleroderma, poly/dermatomyositis)
  • Drugs
  • Hypersensitivity pneumonitis
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14
Q

Fibrosis with ggo

A
  • Desquamative interstitial pneumonitis (DIP)
    • diffuse, patchy ggo
    • architectural distortion
    • septal thickening - uncommon
    • basilar predominance
  • Organizing pneumonia
  • NSIP
  • Connective tissue disorders
  • RB-ILD
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15
Q

Pneumocystis jiroveci Pneumonia (PCP)

A
  • upper lung predominance
  • reticulonodular opacities
  • pneumatocele formation
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16
Q

Mosaic Attenuation

  • Inspiration: patchy areas of dark lung with attenuated vessels indicates dark lung bad
  • Expiration: normal lung becomes more opaque, accentuating darker areas, indicative of air trapping
A
  • Bronchiolitis obliterans
  • Chronic thromboembolism
  • Vasculitis
17
Q

Diffuse thin-walled cystic lung changes

A
  • Lymphangioleimyomatosis (LAM) - child bearing age; non-smoker; round, thin-walled cysts of varying size; no nodule
  • Langerhans cell histiocytosis (LCH) - child bearing age; smoker; irregularly shaped cysts; centrilobular nodule
  • Centrilobular emphysema
  • BAC
  • Wegener’s
  • Cystic metastatic disease
18
Q

Cystic fibrosis

A
  • Bronchial wall thickening
  • Traction bronchiectasis
  • Signet-ring sign
  • Tree-in-bud pattern
  • Mosaic attenuation