Difficult Past Paper Questions Flashcards
Drooping of eyelid, and hurts to move in all directions, pupil constricted – Cavernous sinus aneurysm? Migraine? TIA?
Cavernous Sinus Aneurysm: Presents with cavernous sinus syndrome. This comprises of unilateral and isolated CN III, IV and VI palsy. There is also painful opthalmoplegia, proptosis, ocular bruit. Pupils in midposition and nonreactive if both sympathetic and parasympathetic function is affected in CN III.
Dysphagia, weight loss, regurgitation, crackles in R base – Hiatus Hernia? Achalasia? Post cricoid web?
Achalasia: Patients usually have long history of intermittent dysphagia, characteristically for both liquids and solids from the onset. Regurgitation of food from dilated oesophagus occurs, particularly at night and aspiration pneumonia is a complication. Weight loss is usually not marked. ‘Bird’s beak’ appearance on barium swallow.
Young man with urethritis and obstructive urinary symptoms
Urethral stricture: Urethritis due to gonorrhoea or Chlamydia can result in urethral stricture which is the commonest cause in young men.
Tender hepatomegaly, raised JVP, ascites, AF. Ca-125 is 40 – Heart failure? Ca ovary? Meigs syndrome? Krukenberg’s tumour? Liver cirrhosis?
Heart failure (Ca 125 < 35 is normal)
Lymph node biopsy had 5% larger cells – CLL/Hodgkins/NHL?
NHL: Diffuse Large Cell Lymphoma is subtype (CLL may contain blasts, but these are not found in lymph node biopsy)
Most common site for pancreatic cancer – Head? Tail? Body?
Head = 75%
Haemophilia: mum is carrier, dad has disease – what is chance of getting it?
50%
Renal transplant treated with immunosupressants. Lesion with keratinising centre on arm – SCC? Kaposi’s sarcoma?
Squamous Cell Carcinoma: presents as an indurated keratinising or crusted tumour that may ulcerate. Common in sun exposed areas. Bleeding may occur from the tumour.
DKA patient comes in with persistent vomiting, then vomits up a large amount of blood – Acute gastritis? Oesophagitis? Duodenal Ulcer? Gastric ulcer?
Oesophagitis: Coffee ground vomiting occurs in a minority of patients this tends to originate from erosion of the oesophagus.
Which the most likely indicator of a bowel perforation – Rigidity? Abdominal distension?
Rigidity: board-like
Naloxone indications – RR of 7? Pinpoint pupils?
RR of 7
DIC clotting results?
Elevated PT, elevated aPTT, low platelet, low fibrinogen, and high D-dimer.
Old woman with fractured NOF and also has asthma. Which analgesic do you give – Ibuprofen? Diclofenac? Codeine? Morphine?
Codeine: morphine too strong for 1st-line treatment in old woman
Which metastases are sclerotic to spine – Prostate. Lung. Bronchus. Thyroid. Kidney.
Prostate: called blastic bone mets
Young woman unable to close eye and drooping one side of face, and facial discomfort. – Bell’s palsy? Ramsay Hunt?
Ramsay-Hunt: pain differentiates from Bell’s Palsy
Pt has MI, 2 days later new murmur and unwell. Harsh systolic murmur – Papillary muscle rupture? AS?
Papillary muscle rupture: worsening mitral regurgitation
Lady with previous mastectomy for Breast Ca 4 years ago. Has become thirsty, polyuria and constipated. Now confused. No focal neurology – Cerebellar mets? Hyponatraemia? Hypercalcaemia? Infection? T2DM?
Hypercalcaemia
What is the biggest intervention in a young person to reduce overall cancer risk – Lose weight? Protection during sex? Stop smoking? Alcohol control? Increase exercise?
Stop smoking
Patient has pain on walking. Angio shows calcified distal aorta and femorals on both sides. – Stent? Aortic-bifemoral bypass graft? Embolectomy? Aortic endarterectomy?
Aortic-bifemoral bypass graft
Old man is anaemic, newly constipated and has had weight loss for 6 months. – Sigmoid Ca? Caecal angiodysplasia? Small bowel cancer? Ulcerative colitis? Diverticulitis?
Sigmoid cancer
but could be caecal cancer, as this is more likely to give anaemia, whereas sigmoid cancer presents with fresh blood
Lady is pre-op and will need a GA. He has RA in hands, knees, hips and neck. She has HTN (150ish) and T2DM. What is the most important pre-op check – Cervical XR? FBC? BP monitoring? Glucose finger prick? ECHO?
Cervical X-Ray: need to intubate as undergoing GA
Young athlete (25) keeps fainting. ECG shows sinus rhythm with narrow QRS and long QT. What arrhythmia is happening – Asystole? SVT? AF? Sick sinus syndrome? Irregular ventricular arrhythmia?
Irregular ventricular arrhythmia: Torsade de pointes
Most important thing to correct in DKA – Hyperglycaemia? Fluids? Acidosis?
Fluids
Patient with sudden pale, cold, clamy, pulseless leg, has AF. Best management?
Embolectomy (thrombolysis if this fails)
Teenage boy with tender lumps in breasts on both sides. What investigation – Leave and observe? Biopsy? Mammogram? FNA? Lumpectomy?
Leave and observe: normal puberty
Antidote to TCA overdose
IV sodium bicarbonate (also give activated charcoal if present within 2hrs)
Pt has stroke affecting R arm, R leg and inattention. Where is the stroke – L internal capsule? L thalamus? Occipital lobe? Pons? R internal capsule?
Left thalamus
Man admitted for nasal polyp removal. He is T1DM. What is the best way to control his sugars – Increase insulin? Don’t fast for procedure? Insulin sliding scale until eating and drinking normally? Insulin sliding scale until the operation ends? Continue insulin on the day of surgery? Regular BM monitoring only?
Insulin sliding scale until eating and drinking normally
L sided homonymous Hemianopia. Where is the lesion – L occipital? Optic chiasm? L lateral geniculate nucleus? R occipital?
Right occipital (will be macula sparing)
Patient collapses in garden. P waves – 75, ventricular rate is 40. Wide QRS – WPW? First degree heart block? Second degree (2:1)? Complete heart block? AF?
Complete heart block: due to wide QRS
Old lady is brought in by daughter. She has been deteriorating for 3 days. Has been noticed by neighbours shouting and banging during the night and appears dishevelled – Depression? Dementia? Delirium? Schizophrenia? Anxiety?
Delirium
28 year old painter has pain. It hurts when he grips brushes and when he paints. On examination there is pain in the lateral epicondyle. What action causes pain – Wrist flexion? Thumb flexion? Elbow flexion? Elbow extension? Wrist extension? Finger flexion?
Wrist extension
Old lady has lesion on her labia majora which is ulcerated. What is the cell type on biopsy – BCC? SCC?
SCC
Patient has leg weakness that has spread to the arms over last day. Sensation is only minimally affected – Demyelinating peripheral neuropathy? Destructive something? Amyloid infiltration?
Demyelinating peripheral neuropathy = GBS!
Patient has nosebleed. How do you manage – Tilt head back pinch bridge? Tilt head back pinch nostrils? Tilt head forward pinch bridge? Tilt head back pinch nostrils? Pack with tampax?
Tilt head forward pinch bridge
Patient jumps during sports. Falls over and lands on right leg with it bent and twisted. Comes to A+E with leg in flexion at 30 degrees, O/E you can’t move it passively beyond 30 degrees. – Medial collateral ligament? Medial meniscus? Patella fracture? Tibeal osteochondral fracture? Femur condyle fracture?
Medial meniscus tear: can’t extend leg
Which drug is commonly co-prescribed with morphine – Aspirin? Hyoscine? Co-danthramer? Loperamide?
Co-danthramer
Lady with palmar erythema, raised ALT, raised bilirubin, strongly positive ANA – Autoimmune hepatitis? SLE? Drug-induced cholestasis? PBC?
Autoimmune hepatitis (also has anti-smooth muscle antibodies)
Haematemesis and abdo pain, BP 120/80, HR >100 What do you give IV whilst waiting for endoscopy – IV crystalloid? O-ve blood? IV terlipressin? IV
PPI?
IV crystalloid (terlipressin only in variceal bleeding, PPIs only post-endoscopy)
Diabetic with weakness in all four limbs started 3 days ago, weakness worse proximally vs distally in LL, no change to sensation in LL, UL has some pins and needles, bilateral eyelid weakness. Loss of reflex and plantar response – GBS? Myasthenia? Diabetic
neuropathy? MS?
Myasthenia Gravis
Some guy flew in from Tel Aviv he has chest pain and then a few hours later his leg goes white and there are no pulses – Aortic dissection? Thromboses of the popliteal artery? PE? MI? DVT?
Thromboses of the popliteal artery (from mural thrombus)
Patient has bad claudication and can only walk 10m. Distal aorta and both iliac vessels occluded – Endarterectomy? Femoral crossover bypass? Aorto bifemoral bypass?
Aorto bifemoral bypass: do this for thrombosis if groin arteries, like iliac
Guy gets claudication in calf. Where is the block – Superficial Femoral Artery, posterior tibial, common iliac
Superficial Femoral Artery = calf pain
Iliac artery = bum pain
Man does not open his eyes, localises to pain, groaning. What airway is right for him – Nasopharyngeal? Oropharyngeal? Cuffed endotracheal? LMA? Tracheostomy?
Cuffed endotracheal
Lady with RA and purple nodule on shin ulcerating with raised edges – Pyoderma gangrenosum? SCC? Venous ulcer?
Pyoderma gangrenosum
Guy with pneumonia with green sputum, hyponatraemia, euvolaemic. Initial treatment – Fluid restrict? Oral vasopressin antagonist? Normal saline?
Fluid restrict (SIADH)
Man had 1cm painless penile ulcer on the shaft – Neisseria? Gonorrhoea? Chlamydia Trachomatis? Treponema Pallidum? Herpes simplex?
Treponema Pallidum (Painful = herpes, chancroid Painless = syphillis, lymphogranuloma venereum)
Somebody comes in to A&E with drug resistant TB, where do you keep them – Side room + respiratory measures for staff? Negative pressure room + respiratory measures for staff?
Negative pressure room + respiratory measures for staff
A man with stab injury to the back - hemisection of the cord. Where would he lose pain sensation from?
Contralateral side to weakness
Which of the DMARDs cause retinopathy?
Hydroxychloroquine
Which of the DMARDs cause azoospermia and bone marrow suppression?
Sulfasalazine
Lady from some Pakistan with HTN controlled on amlodipine and BP of 150/90 has retinal findings: blot haemorrhages and yellow deposits (hard exudates I
think) on macula. What is this – Hypertensive retinopathy? Diabetic retinopathy?
Hypertensive retinopathy (macula involved in diabetic maculopathy, not retinopathy)