Differentials For Symptom Histories Flashcards

1
Q

What are the differentials for loss of consciousness?

A

ACS

Ventricular arrhythmias

AV block (HB)

Acute AF

CHF

Hypovolaemia

Aortic stenosis

Neurally mediated syncope (precipitated by stimuli)

Orthostatic hypotension

Migraine

Seizure

Uncommon:
Aortic dissection
Cardiac tamponade
PE
Long QT syndrome
Hypertrophic cardiomyopathy 
Mitral stenosis
Cardiac sarcoidosis

Hypoglycaemia
Acute vertebrobasilar stroke
Pseudosyncope (GAD, Depression etc)

Addison’s disease
Ectopic pregnancy

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2
Q

What are the differentials for sudden onset severe abdominal pain with hypotension and poor peripheral perfusion?

A

Ruptured or leaking abdominal aortic aneurysm

Acute pancreatitis

Biliary colic

Acute cholangitis

Perforated viscus (bowel or gastro/duodenal ulcer)

Acute mesenteric occlusion

Above the diaphragm:
Basal pneumonia
Inferior MI

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3
Q

What are common differentials for chest pain?

A
ACS
Stable Angina
Aortic dissection 
HF
Aortic stenosis
Pericarditis

Pneumonia
PE

Oesophageal reflux - GORD
Acute pancreatitis
Acute cholecystitis
Gastritis

Costochondritis
Trauma

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4
Q

What are the differentials for a lump in the neck?

A

Malignant or inflammatory lymphadenopathy
(Inflammatory are painful normally, malignant are more often painless)

Goitre or thyroid cancer (cancer is rare)

Salivary gland lumps (most often parotid lump)

Lipoma

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5
Q

What are common differentials for blood in stools?

A
Anal fissure
Haemorrhoids 
IBD
Anal cancer
Colorectal cancer
Acute proctitis
Gastroenteritis (dysentery)
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6
Q

What are the differentials for constipation?

A

Primary constipation:

Slow transit constipation
Dyssynergic defecation
IBS
(Due to disordered regulation of colonic and anorectal neuromuscular functions as well as brain-gut neuroenteric disorders)

Secondary constipation:
Metabolic disturbances (hypercalcaemia, hypothyroidism)
Medicines (e.g., opiates, CCBs, antipsychotics)
Neurological disorders (Parkinsonism, spinal cord lesions, diabetes mellitus)
Primary diseases of the colon (stricture, cancer, anal fissure, proctitis).

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7
Q

From outside, then head to toe, what are the differentials for tiredness?

A

Outside: poor sleep, stressful job, caring for someone/children

Head: Depression
Neck: hypothyroidism, viral illness
Chest: cardiac failure, breast/lung cancer
Abdomen: anaemia (NSAIDS), diabetes, renal failure, liver failure, colorectal cancer
Pelvis: menorrhagia, prostate cancer

Check for anaemia of chronic disease: PMH

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8
Q

What are the differentials for falls with no LOC?

A

Postural hypotension

Mechanical fall

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9
Q

What are the differentials for fever?

A
<3 weeks duration :
Self-limiting viral infection 
Uncomplicated bacterial infection (e.g. flu)
Meningitis
Hepatitis
Pancreatitis
>3 weeks duration:
TB
Abscess
Infectious endocarditis 
Malignancy
Autoimmune e.g. vasculitis
Drug induced fever (changes in dose/starting new meds)
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10
Q

What are the differentials for rash?

Note: use SOCRATES for rashes

A
Meningitis 
Atopic Eczema
Psoriasis
Contact dermatitis
Seborrhoeic dermatitis
HUS or TTP
Cellulitis 
Others
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11
Q

What are the differentials for bruising?

A

Henoch–Schönlein purpura
Thrombocytopenia due to: malignancy, marrow failure, haematological malignancy, uremia, autoimmune disorders.
Haemophilia A or B
Von willebrands disease
Simple trauma
Liver failure: alcoholic liver disease, hepatitis, drug-induced damage.
Drugs: warfarin, aspirin, steroids

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12
Q

Differentials for chest pain?

A
Stable angina 
GORD
MSK - costochondritis
Pneumonia
ACS
Aortic dissection
PE
Tension pneumothorax
Pericarditis

Angina: Rad to arm/jaw, only assoc SOB (not sweating, nausea or vomiting), pain lasts for 20 mins max at rest and relieved by GTN
GORD: Burning sensation, worse; lying flat/large meals/bending/straining, relief; swallowing water/saliva/antacids, assoc regurgitation and sour taste
Musculoskeletal: localised pleuritic pain, no assoc symptoms, possible hx of trauma
Pneumonia: hx of cough/purulent sputum/malaise/fever, pleuritic pain with assoc haemoptysis/wheeze/SOB, possible hx of respiratory disease
ACS: severe crushing pain WITH SOB/nausea/vomiting/sweating, rad to arm/jaw, hx of angina
Aortic dissection: tearing/ripping pain felt between shoulder blades, hx of traffic accident/HTN, assoc ischemic limbs/stroke/MI
PE: pleuritic pain, assoc SOB/fever/haemoptysis, possible unilateral swollen hot tender leg prev, RFs; malignancy/pregnancy/clotting disorders/long haul flights/surgery
Tension pneumothorax: pleuritic pain and SOB, hx of lung disease or recent chest trauma (including central line insertion)
Pericarditis: pleuritic pain, worse on coughing

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13
Q

Differentials for acute Dyspnoea?

A

Asthma exacerbation - triggers, diurnal variation
Pneumonia - pleurisy, haemoptysis
Acute pulmonary oedema - orthop

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