Differential / Work-Up by CC Flashcards
Headache
- Migraine
- Tension
- Cluster
- SAH (non-contrast head CT, +/- LP, coags)
- Intracranial neoplasm, abscess (MRI)
- Inc ICP / pseudotumor cerebri (LP - opening pressure)
- Meningitis / encephalitis (CBC, LP)
- CNS vasculitis (ESR, CRP)
- Temporal arteritis (ESR, CRP, biopsy)
- TMJ
- Trigeminal neuralgia
- Carotid or Vertebral dissection (doppler, CT-angio)
- Sinusitis (CBC, sinus CT)
- HTN
- Intracranial hemorrhage (non-contrast head CT)
- Intracranial venous thrombosis
- Caffeine withdrawal
Confusion / Memory Loss
- Az
- Lewy body dementia
- Vascular dementia
- Depression
- Normal pressure hydrocephalus
- Frontotemporal dementia
- Intracranial hemorrhage
- CJD (brain biopsy)
- Neuro-syphilis or HIV dementia
- Hypothyroid, B12 def
- TIA (ECHO, ECG, head imaging)
- Hypoglycemia
Work-Up: CBC, BMP, VLDR/RPR, B12, TSH, CT head +/- MRI, depression screen, LP with opening pressure if normal pressure hydrocephalus
Vision Loss
- Retinal artery occlusion
- Acute angle-closure Glaucoma
- Retinal vein occlusion
- Retinal detachment
- Temporal arteritis
Work - Up: fluorescein angiogram, tonometry, ECHO, carotid doppler, ESR, CRP, temporal artery biopsy
Depression
- MDD
- Bipolar disorder I and II
- Normal bereavement
- Adjustment disorder
- PTSD
- MDD w/ psychotic features
- Schizoaffective
- Dysthymic
- Cyclothymic
- Substance induced depressive disorder
Work-Up: Beck’s Depression Inventory, CBC, TSH, urine tox screen
Psychosis
- Brief psychotic disorder
- Schizophreniform
- Schizophrenia
- Schizoaffective
- MDD w/ psychotic features
- Substance induced
- 2/2 medical condition
- Schizotypal personality disorder
Work-Up: CBC, BMP, LFTs, BUN/Cr, alcohol level, urine drug screen, TSH, Dep Inventory
Dizziness
- Meniere’s (VDLR/RPR)
- Vestibular neuronitis (CBC, audiogram)
- Labyrinthitis (CBC, audiogram)
- BPV (dix hallpike)
- Acoustic neuroma
- Orthostatic hypotension (orthostatic vitals, rectal, CBC, electrolytes)
- Vertebrobasilar stroke (MRI/MRA)
- Brainstem or cerebellar tumor
LOC
- Syncope / orthostatics
- Seizure
- Stroke
- Hypoglycemia
- Sub Use
- MI
- PE
- Arrhythmia or aortic stenosis
Work-Up: EKG, maybe ECHO or Holter monitor, CBC, electrolytes, GLUCOSE, AED levels, drug screen, MI/PE work-up if high suspicion, +/- head imaging
Numbness/Weakness
- Stroke /TIA (CBC, elec, CT head, lipids, EKG, ECHO, carotid dopplers, MRI)
- GBS (LP, nerve conduction studies)
- Polymyositis (CPK)
- Myasthenia gravis (acetylcholine receptor antibodies)
- MS (VDLR/RPR, ESR, MRI)
- ALS
- Todd’s Paralysis (MRI)
- Peripheral neuropathy (Ca, Vit B12, HgbA1c)
- Mult Myeloma (SPEP, UPEP)
- CNS vasculitis (CRP, ESR)
- Syringomyelia (MRI)
- Conversion disorder
Fatigue / Sleepiness
- Sleep apnea
- Insomnia
- Depression
- Hypothyroid
- Anemia
- Shift Work Sleep Disorder
Work Up: CBC, TSH, polysomnography, Beck’s Dep Inventory
Night Sweats
- Tuberculosis (PPD, quantiferon gold, CXR, CBC, sputum gram stain and acid fast stain)
- Leukemia/ lymphoma
- Acute HIV (HIV antibody)
- Hyperthyroid (TSH, free T4)
- Pheochromocytoma (urine catecholamines )
- Carcinoid (5-HIAA)
Sore Throat
- Strep pharyngitis
- Viral pharyngitis
- Epiglossitis
- Retropharyngeal abscess or peritonsillar abscess
- EBV
- Acute HIV
- Postnasal drip 2/2 allergies
- Secondary syphilis
Work Up: pharyngeal cx, CBC w/ peripheral smear, Monospot, HIV antibodies, VLDR/RPR
Cough/ SOB
- COPD exacerbation (sputum cx, CXR)
- Asthma exacerbation (peak expiratory flow measure, pulse ox, CBC, CXR)
- PNA (CBC, CXR)
- Atypical pneumonia (legionella, mycoplasma IgM)
- CHF / pulmonary edema (CXR, ECHO, BNP)
- PE (ct angio?)
- Pneumothorax (CXR)
- MI (ECG, troponin, CXR)
- Viral URI
- Lung cx
- GERD
- Pulmonary vasculitis (ANCA)
- Pneumonitis
- Foreign body in airway (lateral decubitus films or insp/exp films)
- Bronchitis
- Tb / lymphoma / mets/ HIV / sarcoidosis (PPD, CXR, sputum x with acid fast stain, HIV antibody)
- Mitral stenosis, valve disease
- Arrhythmia, A fib (ECG)
CP
- PE
- PTX
- PNA
- Cardiac tamponade
- MI
- Aortic dissection
- GERD
- CHF exacerbation
- Pericarditis, myocarditis
- Pancreatitis/ esophagitis/ PUD
- Esophageal spasm
- MSK / ribs
- Herpes zoster
- Sickle cell acute chest
Work Up: ECG, CXR, trop, d-dimer or CT-angio, CBC (reticulocyte count and smear), electrolytes, possible ECHO, stress test if angina, barium swallow, manometry, EGD w/ H pylori
Palpitations
- A fib, dysrhythmia
- Hypoglycemia
- Panic attack
- Hyperthyroidism
- Pheochromocytoma
- Carcinoid syndrome
- MV prolapse
- Sub use
Work-Up: EKG, CBC, elec, glucose, TSH, +/- urine catecholamines and 5-HIAA, ECHO and holter if poss MV prolapse, urine tox
Wt Loss
- anorexia
- depression
- chron’s / UC / malabsorption
- cx
- HIV, Tb
- Hyperthyroid
Work-Up: CBC, TSH, elec, HIV antibodies, quant gold, dep screen, urine tox,