Differential diagnosis and mini cases - Erectile dysfunction, Amenorrhea, Vaginal bleeding, Vaginal discharge, Dyspareunia, Abuse, Limb/joint pain Flashcards
Why is Erectile dysfunction such an important topic to disscuss with the patient ?
- affects patient’s sexual life;
- affects patient’s self image;
- effective treatments now available;
- ED may be a sign of important comorbid CV disease !
- Ed is a strong predictor ob both : coronary artery disease and peripheral artery disease as endothelial dysfunction contributes to all three conditions !
Erectile dysfunction - key history ?
- Duration ?
- Severity ?
- Presence/absence of nocturnal erections ?
- Change in libido ?
- Stress or depression ?
- Trauma ?
- Associated incontinence ?
- Gynecomastia or loss of body hair ?
- Medications (and recent changes) ?
- Medical history (hypertension, diabetes, high cholesterol, known atherosclerotic vascular disease, prior prostate surgery, liver disease, thyroid disease, neurologic disease) ?
- SAD : Smoking, Alcohol, Drug use.
What is the key physical exam in erectile dysfunction ?
- Vital signs;
- Cardiovascular exam;
- Genital and rectal exams;
What should be your differential diagnosis when tackling an erectile dysfunction case ?
- Psychogenic ED
- Vascular ED
- Drug induced ED
- Hormonal ED - thyroid, pituitary, gonadal
- Hormonal ED - diabetics
- Neurogenic ED
- Other causes :
- urologic
- renal disease
- sickle cell disease
- sleep disorders
- liver disorders
How tactfully you can start an interview with a patient c/o erectile dysfunction ?
- Many men have occasional problems getting or keeping an erection. Has this ever happened to you ?
- I always ask my patients some very personal questions related to their health. Do you ever have any problems with sexual intercourse ? With erections ?
- I’m glad you feel comfortable telling me about this . I’d like to ask you some specific questions about your sexual function to figure out what we should do.
- Be nonjudgemental;
- Use professional language;
- Normalize your questions by reminding patients how common ED is !
- It’s common, it’s treatable, it’s an appropriate topic to discuss with your doctor;
- Sometimes its good to overcome patient hesitance by asking direct questions first and later returning to open questions;
What alarm symptoms you must seek in a patient presenting with ED ?
- Concurrent hip and buttock cramps with walking :
- Abdominal aortic aneurysm
- Intermittent claudication
- Spinal stenosis
- Leg weakness or numbness, perineal numbness :
- Spinal cord compression or pelvic mass
- Nerve root compression
- Peripheral neuropathy
- Bowel or bladder incontinence :
- Spinal cord compression or pelvic mass
- Bladder infection
- Fecal impaction
- Galactorrhea :
- Pituitary tumoe
- Abnormal secpndary characteristics : loss of beard, loss of body hair, female body habitus :
- Pituitary tumor
- Visual fields cuts - loss of portions of vision :
- Pituitary tumor
What focused questions do you have to ask to a patient presenting with erectile dysfunction ?
- History of depression or any other psychiatric condition ?
- Loss of interest, trouble concentrating, trouble with memory, feelings of sadness ?
- Difficulties with relationship with partner ?
- Performance anxiety ?
- Do you smoke ? drink ? use drugs ?
- Do you have high cholesterol, hugh blood pressure, chest pain, leg pain while you walk ?
- Do you have history of CAD ? Do any members in your family ? Is there any history of PAD ?
- Have you ever had any pelvic trauma, surgeries, radiation tx ?
- Do you feel any numbness in genital area ?
- Have you been experiecing any bowels problems - like noticing any stool in your underwear ?
- Have you ever experienced urine incontinence ?
- Have you ever felt any foot or leg numbness or weakness ?
- Are you taking any medications ? Like medicines to lower high blood pressure, antidepressants, antiandrogenics, antihistamines, corticosteroids, digitals ? (look for : hydrochlorothiazide, SSRI, B-blockers)
- Do you ever drive under the influance of an alcohol ?
- CAGE : Have you ever tried to cut down your alcohol drinking ? Do you get angry when others ask about your alcohol use ? Do you feel guilty about your drinking ? Do you drink a morning eye-opener ?
- Do you have a history of : thyroid disorder ? heat/cold intolerance ? constipation/diarrhea ? weight loss/gain ? tremor ? gonadal disease ? gynecomastia ? loss of body hair ? decreased in testicular size ? pituitary disease ? visual field cuts ? headache ? decreased libido ? diabetes ? Polyphagia, Polyuria, Polydypsia ? renal disease ? bone pain ?
- Do erections take longer to achieve and have shorter duration and are of less rigidity ?
- Was the onset : sudden ? gradual ? intermittent ?
- Do you achieve normal erection, but lose it too early ?
- Is there a painful bending of penis with erections ?
- Is it better with : another partner ? masturbation ? visual stimuli ? nocturnal or morning erections ?
What is your differential diagnosis and workup plan ?
“47 yo M presents with impotence that started 3 months ago. He has hypertension and was started on atenolol 4 months ago. He also has diabetes and is on insulin”
- Differential diagnosis :
- Drug-related ED
- ED caused by hypertension
- ED caused by diabetes mellitus
- Psychogenic ED
- Peyronie’s disease
- Workup plan :
- Genital exam
- Rectal exam
- Glucose
- CBC
- Testosterone level
Amenorrhea - key history ?
- FLAG HIV WC
- Fatigue
- Libido
- Anorexia, Anxiety&depression
- Gonorrhea (STDs), Galactorrhea (PRL)
- Hair and skin change, Headaches, Hot flushes
- Insomnia
- Visual change, Voice change
- WAD => Weight, Appetite, Diet
- Cold intolerance, Constipation
- Primary vs. secondary ?
- Duration ?
- Possible pregnancy ?
- Associated symptoms : headache, decreased peripheral vision, galactorrhea, hirsutism, virilization, hot flashes, vaginal dryness, symptoms of thyroid disease ?
- History of anorexia nervosa, excessive dieting, vigorous exercise, pregnancies, D&Cs, uterine infections ?
- Drug use ?
- Medications ?
What is the key physical exam in case of amenorrhea ?
- Head and neck => oropharynx, visual field, thyroid, lymohadenopathy;
- Abdominal => inspection, auscultation, percussion, palpation;
- Order pelvic exam;
- Order breat exam;
Define primary and secondary amenorrhea !
- Primary amenorrhea :
- If a girl is >16 yo, has developed secondary sexual characteristics, but still has’n got her period;
- If a girl >14 and has not started developing secondary sexual characteristics;
- Seconary amenorrhea :
- If a female has had periods for at least 9 months and has been missing them for the past 3 months !
- Or missing 3 periods in a female with previous oligomenorrhea;
Define Hypothalamic or functional amenorrhea.
Disorder of GnRH release resulting from loss of the LH surge and anovulation.
What are the major constitutients of PCOS ?
- Hirsutism - excessive body and facial hair
- Overweight
- Menstrual abnormalities
- Infertility
- Enlarged ovaries
What is a postpill amenorrhea ?
Failure to resume ovulation 6 months after discontinuing hormonal contraception.
Give differential diagnosis of primary and secondary amenorrhea!
- Primary amenorrhea :
- Pregnancy
- Gonadal dysgenesis
- Contitutional delay
- Mullerian dysgenesis
- Androgen insensitivity
- Prolactin-secreting tumor
- Stress, weight loss, anorexia - hypothalamic amenorrhea
- Congenital adrenal hyperplasia
- Obstructed outflow tract - transverse vaginal septum, imperforate hymen
- Kallman syndrome
- Secondary amenorrhea :
- Pregnancy
- Ovarian disease - PCOS, Premature ovarian failure
- Hypothalamic dysfunction - stress, weight loss, anorexia, bulimia
- Infiltrative lesions or tumors
- Pituitary disease - Prolactin-secreting tumor, empty sella syndrome, Sheehan syndrome, Adrenocorticotropic hormone secreting tumor, GH-secreting tumor
- Uterine : Asherman’s syndrome
- Other : nonclassic adrenal hyperplasia, drug induced, postpill amenorrhea
List reversible and irreversible causes of amenorrhea.
- Reversible :
- Imperforate hymen
- Ascherman’s syndrome
- PCOS
- Hyperprolactinemia
- Postpill amenorrhea
- Drug induced
- Exercise, stress, weight loss induced
- Systsemic ilness
- Irriversible :
- Empty sella syndrome
- Cushing’s syndrome
- Kallmann syndrome
- Gonadal dysgenesia
- Mullerian defects
- Andrgen insensitivity syndrome
How should you start taking history form a patient c/o amenorrhea ?
- Let the patient speak with her own words and as always start with open-ended questions and do not interrupt !
- Assess overall health;
- Tell me more about your periods.
- At what age did your periods begin ?
- When did your last period begin ?
- Do you have regular periods ?
- What is your usual cycle lenght ?
- Could you be pregnant ?
What important aspects come to your mind when you think you are about to interview a patient c/o amenorrhea ?
- Explore the possibility of pregnancy !
- Assess for alarm symptoms : recent unprotected intercourse (pregnancy), headaches + galactorrhea + loss of peripheral vision (pituitary tumor), body weight 15% below ideal and impaired body image (anorexia);
- Classify : primary (congenital, genetic) or secondary amenorrhea ?
- Detailed O&G history :
- LMP RTV CS PAP
- LMP
- Menarche
- Period
- Regularity
- Tampoons and pads
- Vaginal - discharge, itching, dryness
- Cramping
- Spotting
- Pregnancy
- Abortion, miscarriage
- PAP smear and gynecological exam
What focused questions will you ask a patient presenting with amenorrhea ?
- Have you had an unprotected intercourse ?
- Have you had morning nausea ?
- Have you noticed that most of your friends have developed pubic hair and breats before you ?
- Are most of your firends taller than you ?
- Have you lost/gained weight recently ?
- Have you been told that you exercise too much ?
- Have you been under greater than usual psychosocial stress ?
- Do you have impaired sense of smell ?
- Have you been diagnosed with chornic kidney disease, thyroid disease, sarcoidosis, lymphoma, histiocytosis X, juvenile rheumathoid arthritis ?
- Are you taking any medications ?
- Have you taken OCPs in the past year ?
- Have you ever had a uterine surgical procedure, infection, abortion ?
- Have you been pregant recently ?
- If you recently gave birth, were there any complications ?
- Have you ever been exposed to high doses of radiation ?
- Have you ever received chemotherapy ?
- Have you recently experienced hot flashes, night sweats, mood changes, vaginal dryness ?
- Have you noticed acne or facial hair ?
- Have you noticed heat or cold intolerance, a change in energy level, weight loos or gain, diarrhea or constipation, heart palpitations, change in hair or skin texture ?
- Have you had headaches, changes in your mood or personality ?
- Have you experienced fatigue, anorexia, weight loss, fever ?
- Do you have a chronic cough or difficulty breathing ?
- Have you had depressed mood lately ?
What is your differential diagnosis and workup plan ?
“40 yo F presents with amenorrhea, morning nausea and vomiting, fatigue, and polyuria. Her last menstrual period was 6 weeks ago, and her breasts are full and tender. She uses the rhythm method for contraception”
- Differential diagnosis :
- Pregnancy
- Prolactinoma
- Anovulatory cycle
- UTI
- Hyperthyroidism
- Workup plan :
- Urine hCG
- U/s - abdomen, pevis
- Pevlic exam
- CBC, UA, urine culture
- Prolactin, TSH, FSH, LH
- PAP smear
- Cervical cultures, rubella antibody, HIV antibody/p24 antigen, hepatitis B surface antigen, VDRL/RPR
What is your differential diagnosis and workup plan ?
“23 yo obese F presents with amenorrhea for 6 months, facial hair, infertility for the past 3 yrs”
- Differential diagnosis :
- Polycystic ovary syndrome
- Hyperandogenism
- Thyroid disease
- Hyperprolactinemia
- Pregnancy
- Ovarian or adrenal malignacy
- Premature ovarian failure
- Workup plan :
- Urine hCG
- LH/FSH, TSH, prolactin
- Pelvic exam
- Testosterone, DHEAS
What is your differential diagnosis and workup plan ?
“35 yo F presents with amenorrhea, galactorrhea, visual field defects, and headaches for the past 6 months”
- Differential diagnosis :
- Amenorrhea secondary to prolactinoma
- Pregnancy
- Thyroid disease
- Premature ovarian failure
- Pituitary tumor
- Workup plan :
- Urine hCG
- LH/FSH, TSH, prolactin
- MRI—brain
- Pelvic and breast exams
What is you differential diagnosis and workup plan ?
“48 yo F presents with amenorrhea for the past 6 months accompanied by hot flashes, night sweats, emotional lability, and dyspareunia”
- Differential diagnosis :
- Menopause
- Pregnancy
- Pituitary tumor
- Thyroid disease
- Workup plan :
- Urine hCG
- LH/FSH, TSH, prolactin
- Testosterone, DHEAS
- Pelvic exam
- CBC
- MRI—brain
What is your differential diagnosis and workup plan ?
“35 yo F presents with amenorrhea, cold intolerance, coarse hair, weight loss, and fatigue. She has a history of abruptio placentae followed by hypovolemic shock and failure of lactation 2 years ago”
- Differential diagnosis :
- Sheehan’s syndrome
- Premature ovarian failure
- Pituitary tumor
- Thyroid disease
- Asherman’s syndrome
- Workup plan :
- Urine hCG
- LH/FSH, prolactin
- CBC
- Pelvic exam
- TSH, FT4
- ACTH
- MRI—brain
- Hysteroscopy
What is your differential diagnosis and workup plan ?
“18 yo F presents with amenorrhea for the past 4 months. She is 5 feet, 6 inches (167.6 cm) and weighs 90 lbs (40.9 kg). She has a history of exercise and heat intolerance”
- Differential diagnosis :
- Pregnancy
- Anerexia nervosa
- Hyperthyroidism
- Workup plan :
- Urine hCG
- CBC
- TSH, FT4
- LH/FSH
What is your differential diagnosis and workup plan ?
“29 yo F presents with amenorrhea for the past 6 months. She has a history of occasional palpitations and dizziness. She lost her fiancé in a car accident in which she was a passenger”
- Differential diagnosis :
- Anxiety-induced amenorrhea
- Posttraumatic stress disorder
- Depression
- Hyperthyroidism
- Workup plan :
- CBC
- TSH, FT4
- Urine cortisol level
- Progesterone challenge test
- LH/FSH, estradiol levels
Vaginal bleeding - key history ?
- Pre- vs. postmenopausal status ?
- Duration ?
- Amount ?
- Menstrual history and relation to last
discharge; - Pelvic or abdominal pain ?
- Urinary symptoms;
- Trauma;
- Medications (especially blood thinners, contracep- tives);
- History of easy bleeding or bruising;
- History of abnormal Pap smears.
Vaginal bleeding - key physical exam ?
- Vital signs and general appearence : body habitus - is the patient over or underweight ?
- HEENT : other sites of bleeding ?
- Skin : look for petachiae or purpura; notice hair distribution and quality;
- Abdominal exam : distention, bowel sounds, liver and spleen size, abdominal masses and tenderness;
- Complete pelvic exam;
Give differential diagnosis of Abnormal Uterine Bleeding.
- Structural : PALM
- Polyps
- Adenomyosis
- Leiomyoma
- Malignancy and hyperplasia
- Nonstructural : COEIN
- Coagulopathy
- Ovulatory dysfunction
- Endometrial infection or inflammation
- Iatrogenic
- Not yet classified
- Pregnancy and pregnancy related :
- Placental abruption
- Ectopic pregancy
Define :
- Menometrorrhagia
- Menorrhagia
- Metrorrhagia
- Oligomenorrhea
- Ovulation bleeding
- Polymenorrhea
- Menometrorrhagia - Irregular or excessive bleeding during menstruation and between periods;
- Menorrhagia - Bleeding of excessive flow and duration that occurs at regular intervals.
- Metrorrhagia - Bleeding that occurs at irregular intervals.
- Oligomenorrhea - Bleeding that occurs at intervals > 35 days.
- Ovulation bleeding = single episode of spotting between regular menstrual periods.
- Polymenorrhea = Bleeding that occurs at intervals < 21 days.
Give full differential diagnosis of Abnormal Vaginal Bleeding.
- Complications related to pregnancy :
- Normal intrauterine pregnancy
- Ectopic pregnancy
- Gestational trophoblastic disease
- Spontaneous abortion
- Placenta previa
- Retained products of conception after therapeutic abortion
- Abnormalities of the reproductive tract :
- Benign lesions (cervical, endometrial, adenomyosis)
- Malignant lesions (cervical, endometrial)
- Infection (cervicitis, endometritis)
- Trauma (laceration, abrasion, foreign body)
- Systemic disease :
- Endocrinopathy (hypothyroidism, hyperprolactinemia, Cushing’s disease, PCOS, adrenal dysfunction/tumor)
- Coagulopathy
- Renal disease
- Hepatic disease
- Iatrogenic factors/medications :
- Anticoagulation therapy
- Intrauterine device
- Hormone therapy
- Psychotropic agents
- DUB
Define abortion types : Threatened, Missed, Inevitable and Completed.
- Threatened abortion : diagnostic criteria for spontaneous abortion have not been met, but vaginal bleeding has occurred and the cervical os is closed;
- Missed abortion : refers to clinical abortion in which the products of conception are not expelled spontaneously from the uterus - the woman has a nonviable intrauterine pregnancy that has not been passed and her cervical os is closed; Women may notice that symptoms associated with early pregnancy (eg, nausea, breast tenderness) have abated and they do not “feel pregnant” any more;
- Inevitable abortion : The term inevitable abortion refers to cases in which the patient has vaginal bleeding, typically accompanied by crampy pelvic pain, and the cervix is dilated. Products of conception can often be felt or visualized through the internal cervical os.
- Complete abortion : refers to cases in which the products of conception are entirely out of the uterus and cervix, and on examination the cervix is closed and the uterus is small and well contracted; vaginal bleeding and pain may be mild or may have resolved.
List questions you will ask a patient presenting with Abnormal Uterine Bleeding ?
- Tell me more about your bleeding.
- Do you have any other symptoms?
- What are you most worried about?
- When did the bleeding start?
- Was the onset gradual or sudden?
- Can you describe the bleeding for me? => bright red? brownish? spotting? clots?
- Is the bleeding continous or intermittent?
- How many tampoons or pads do you have to use daily?
- Have you noticed you have been passing some tissues?
- When was your LMP? Is your period late?
- Are your menstrual cycles regular?
- What is the usual interval between periods?
- Describe your typical cycle : how often? how regular? how many days? how heavy?
- Do you have bleeding occurring irregularly between menstrual cycles?
- Are you sexually active? Do you use condoms?
- Do you have bleeding after sexual intercourse?
- Do you have the following symptoms a few days before your period: breast fullness or tenderness, stomach bloating, low back pain, weight gain, mood changes?
- Do you have : Fever? Vaginal discharge or itching? Milky nipple discharge?
- Do you have easy bruising or bleeding from other sites?
- Do you experience hot flashes or night sweats? Heat or cold intolerance?
- What medications are you taking? Do you use OCPs? Have you recently started OCPs? Have you missed a pill?
- Have you had any recent change in weight, chronic illness, or stress?
- Have you recently stopped taking hormonal therapy?
- Is it possible that you are pregnant ? Have you had a previous ectopic pregnancy or PID?
- Have you had a recent pregnancy or a recent abortion?
- Have you been forced to have sexual relations, or have you had sex that was rough or painful?
- Are you having abnormal bleeding from any other site? Have you bruised easily recently?
- Do you have a kidney or liver disease ?
What diagnostic test will you order in a abnormal vaginal bleeding case ?
- CBC, platelet count
- Urine bhCG
- Blood type and cross
- THS, prolactin
- FSH/LH
- INR/PT, aPTT
- Transvaginal ultrasound
- Endometrial biopsy if indicated
- PAP smear
What is your differential diagnosis and workup plan?
“17 yo F presents with prolonged, excessive menstrual bleeding occurring irregularly within the past 6 months”
- Differential diagnosis :
- Dysfunctional uterine bleeding
- Coagulation disorder (von Willebrand’s disease, hemophilia, thrombocytopenia)
- Cervical cancer
- Molar pregnancy
- Hypothyroidism
- Diabetes mellitus
- Workup plan :
- Urine hCG
- Pelvic exam
- Cervical culture, Pap smear
- CBC, ESR
- Glucose
- PT/PTT
- LH/FSH, TSH, prolactin
- U/S—pelvis
What is your differential diagnosis and workup plan ?
“61 yo obese F presents with profuse vaginal bleeding for the past month. Her last menstrual period was 10 years ago. She has a history of hypertension and diabetes mellitus. She is nulliparous”
- Differential diagnosis :
- Endometrial hyperplasia
- Endometrial carcinoma
- Cervical cancer
- Atrophic endometrium
- Leiomyoma
- Endometrial polyp
- Anticoagulant medications
- Workup plan :
- Pelvic exam
- Pap smear
- Endometrial biopsy
- Endometrial curettage
- U/S—pelvis
- Colposcopy
- Hysteroscopy
What is your differential diagnosis and workup plan?
“45 yo G5P5 F presents with postcoital bleeding. She is a cigarette smoker and takes OCPs”
- Differential diagnosis :
- Cervical cancer
- Endometrial hyperplasia
- Endometrial carcinoma
- Cervical polyp
- Cervicitis
- Trauma - cervical laceration
- Workup plan :
- Pelvic exam
- Pap smear
- Colposcopy and biopsy
- HPV testing
- Endometrial biopsy
What is your differential diagnosis and workup plan?
“28 yo F who is 8 weeks pregnant presents with lower abdominal pain and vaginal bleeding”
- Differential diagnosis :
- Spontaneous abortion
- Ectopic pregnancy
- Molar pregnancy
- Workup plan :
- Urine hCG
- Quantitative serum hCG
- U/S—abdomen/pelvis
- Pelvic exam
- CBC
- PT/PTT
What is your differential diagnosis and workup plan?
“32 yo F presents with sudden onset of left lower abdominal pain that radiates to the scapula and back and is associated with vaginal bleeding. Her last menstrual period was 5 weeks ago. She has a history of pelvic inflammatory disease and unprotected intercourse”
- Differential diagnosis :
- Ectopic pregnancy
- Ruptured ovarian cyst
- Ovarian torsion
- Pelvic inflammatory disease
- Workup plan :
- Urine hCG
- Quantitative serum hCG
- U/S—abdomen/pelvis
- Pelvic exam
- Cervical cultures
Vaginal discharge - key history ?
- Amount, color, consistency, odor, duration;
- Associated vaginal burning, pain, pruritus;
- Recent sexual activity;
- Onset of LMP;
- Use of contraceptives, tampons, douches;
- History of similar symptoms;
- History of STDs;
Key physical exam - vaginal discharge ?
- Vital signs;
- Abdominal exam;
- Complete pelvic exam;
What is your differential diagnosis and workup plan ?
“28 yo F presents with a thin, grayish-white, foul- smelling vaginal discharge”?
- Differential diagnosis :
- Bacterial vaginosis
- Vaginitis—candidal
- Vaginitis—trichomonal
- Cervicitis (chlamydia, gonorrhea)
- Workup plan ?
- Pelvic exam
- Wet mount, KOH prep, “whiff test”
- pH of vaginal fluid
- Cervical cultures
What is your differential diagnosis and workup plan ?
“30 yo F presents with a thick, white, cottage cheese–like, odorless vaginal discharge and vaginal itching”
- Differential diagnosis :
- Vaginitis - candidal
- Bacterial vaginosis
- Vaginitis - trichomonal
- Workup plan ?
- Pelvic exam
- Wet mount, KOH prep, “whiff test”
- pH of vaginal fluid
- Cervical cultures
What is your differential diagnosis and workup plan ?
“35 yo F presents with a malodorous, profuse, frothy, greenish vaginal discharge with intense vaginal itching and discomfort”?
- Differential diagnosis :
- Vaginitis - trichomonal
- Vaginitis - candidal
- Bacterial vaginosis
- Cervicitis (chlamydia, gonorrhea)
- Workup plan :
- Pelvic exam
- Wet mount, KOH prep, “whiff test”
- pH of vaginal fluid
- Cervical cultures
Dyspareunia - key history ?
- Duration, timing ?
- Associated symptoms :
- vaginal discharge
- rash
- painful menses
- GI symptoms
- hot flashes
- Adequacy of lubrication;
- Menopausal status;
- Libido;
- Sexual history;
- History of sexual trauma or domestic violence;
- History of endometriosis, pelvic inflammatory disease;
- Prior abdominal/pelvic surgeries;
Dyspareunia - key physical exam ?
- Vital signs;
- Abdominal exam;
- Complete pelvic exam;
What is your differential diagnosis and workup plan ?
“54 yo F c/o painful intercourse. Her last menstrual period was 9 months ago. She has hot flashes”
- Differential diagnosis :
- Atrophic vaginitis
- Endometriosis
- Cervicitis
- Depression
- Domestic violence
- Workup plan :
- Pelvic exam
- LH/FSH
- Wet mount, KOH prep
- Cervical cultures