different repair patterns in different sites

Question 1

skin

Answer 1

repair and regeneration

burns past the deep dermis require engraftment

Question 2

skin: primary healing

Answer 2

when surgeon brings edges of wounds closer together so epidermal cells only need to migrate a short distance

Question 3

skin: secondary healing

Answer 3

whne a large area of hemorrhage and necrosis cannot be corrected surgically completely.

Question 4

liver

Answer 4

tremendous regenerative capacity despite total lack of mitoses
liver regenerates by compensatory hyperplasia (increased cell division) of hepatocytes.

Question 5

kidney

Answer 5

limited regenerative capacity

nephrectomy (removal of kidney) causes hypertrophy of remaining kidney

Question 6

lung

Answer 6

epithelium respiratory tract lineing has some regenerative capabilities

Question 7

heart

Answer 7

very minimal and slow regenerative ability to damaged myocardium. scaring results in loss of contractile elements and decrease of contraction effectiveness in surviving myocardium

Question 8

nervous system

Answer 8

periferal has capacity for axonal regeneration but centeral does not. only regrowht and reorganization of surviving neuronal cell processes can reestablish connections.

Question 9

gliosis in NS

Answer 9

when brain or spinal cord is damaged, this growth in CNS it is equivalent to scar formation

Question 10

PNS

Answer 10

neurons can regenerate their axons

Question 11

traumatic neuroma

Answer 11

resulting from scar or other obstructions preventing perfect alignment for PNS recovery