DIC/Coagulation Problems Flashcards
1
Q
What are triggers of DIC in pregnancy?
A
Retention of dead fetus (of > 20 weeks gestation which has been dead for >3 weeks) Pre-eclampsia Placental abruption Endotoxic shock Amniotic fluid embolism Placenta accreta Hydatidiform mole Prolonged shock from any cause Acute fatty liver of pregnancy
2
Q
What happens in DIC in pregnancy?
A
Thromboplastin are released into the circulation, fibrin and platelets are consumed as intra-vascular clotting occurs
3
Q
What tests for DIC?
A
Kaolin-cephalin clotting time increases (reduced factors II, V, VII)
Reduced fibrinogen
Increased fibrin degeneration products
Cross match blood
Platelets
Partial thromboplastin time
Prothrombin time
4
Q
What management for DIC
A
Presentation may be as heavy bleeding and shock - correct shock O2 at 15L/min via non-rebreathe 2 14G IVI Take bloods Give blood Give FFP
Calcium is sometimes needed to counteract citrate in stored blood- 10ml of 10% calcium glunate
