Diarrhoea in a Transplant Patient Flashcards
What symptoms commonly present in infective diarrhoea?
- Blood in diarrhoea
- Mucous in diarrhoea
- Profuse and watery
- Systemic features of illness
- Fever
- Joint pain
What can cause infective diarrhoea?
- Bacteria
- Viruses
- Parasites
Which bacteria can cause infective diarrhoea?
- Campylobacter sp
- Shigella sp
- Non-typhi salmonella
- E.coli O157
- C.diff
What is another name for bloody diarrhoea?
Dysentery
What are the common viral causes of gastroenteritis?
- Rotavirus
- Norovirus
Which virus can cause gastroenteritis in immunocompromised patients?
CMV - which can cause colitis
What parasites can cause severe diarrhoea in the immunocompromised patients?
- Cryptosporidium
- Isospora belli
- Giardia lamblia
- Cyclospora
- Miicrosporidia
What causes CMV colitis?
Reactivation and proliferation of Cytomegalovirus (CMV)
What is the only CMV infection treatment option in non-HIV immunosuppressed patients?
Ganciclovir
How is CMV transmitted?
Via infected secretions
What are the key features of infections in immunocompromised patients?
- Severe infections can present with mild symptoms
- Common pathogens can cause more severe infections
- Less virulent organisms can cause infections in these patients