Diarrhoea in a Transplant Patient Flashcards

1
Q

What symptoms commonly present in infective diarrhoea?

A
  • Blood in diarrhoea
  • Mucous in diarrhoea
  • Profuse and watery
  • Systemic features of illness
  • Fever
  • Joint pain
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2
Q

What can cause infective diarrhoea?

A
  • Bacteria
  • Viruses
  • Parasites
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3
Q

Which bacteria can cause infective diarrhoea?

A
  • Campylobacter sp
  • Shigella sp
  • Non-typhi salmonella
  • E.coli O157
  • C.diff
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4
Q

What is another name for bloody diarrhoea?

A

Dysentery

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5
Q

What are the common viral causes of gastroenteritis?

A
  • Rotavirus

- Norovirus

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6
Q

Which virus can cause gastroenteritis in immunocompromised patients?

A

CMV - which can cause colitis

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7
Q

What parasites can cause severe diarrhoea in the immunocompromised patients?

A
  • Cryptosporidium
  • Isospora belli
  • Giardia lamblia
  • Cyclospora
  • Miicrosporidia
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8
Q

What causes CMV colitis?

A

Reactivation and proliferation of Cytomegalovirus (CMV)

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9
Q

What is the only CMV infection treatment option in non-HIV immunosuppressed patients?

A

Ganciclovir

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10
Q

How is CMV transmitted?

A

Via infected secretions

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11
Q

What are the key features of infections in immunocompromised patients?

A
  • Severe infections can present with mild symptoms
  • Common pathogens can cause more severe infections
  • Less virulent organisms can cause infections in these patients
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