Diarrhoea Flashcards

1
Q

Cholera - toxin mediated camp phosphorylation of CFTR (galphas) Na and h2o follows

A

Enkephalins - anti AC

Crofelamer - anti CFTR

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2
Q

Motility modifying

A

Antimuscarinics reduce peristalsis and segmental contractions and pain

Opioids reduce peristalsis, inc segmental contraction - smooth muscle and water reabsorption

Side effects: nausea, vomiting and constipation.

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3
Q

Anti inflammatories

A

Sulphalazine

Corticosteroids eg prednisone, dexamethasone

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