Diarrhoea Flashcards
1
Q
Cholera - toxin mediated camp phosphorylation of CFTR (galphas) Na and h2o follows
A
Enkephalins - anti AC
Crofelamer - anti CFTR
2
Q
Motility modifying
A
Antimuscarinics reduce peristalsis and segmental contractions and pain
Opioids reduce peristalsis, inc segmental contraction - smooth muscle and water reabsorption
Side effects: nausea, vomiting and constipation.
3
Q
Anti inflammatories
A
Sulphalazine
Corticosteroids eg prednisone, dexamethasone