Diarrhea Flashcards
Normal stool volume
- 3 to 7 BM/day
-
Normal stool volume
- 3 to 7 BM/day
-
Acute infectious diarrhea
- 20 to 30 BM/day
- up to 20 liters of stool per day
Diarrhea reflects an increase in what?
Water
Reasons for increased water in stool from?
- Increased intestinal secretion of water
2. Decreased intestinal reabsorption of water
Acute diarrhea duration
-
Acute diarrhea duration
Persistent diarrhea
14-30 days
Chronic diarrhea
> 30days
Watery types of diarrhea
Secretory, Osmotic, Functional
Secretory description of diarrhea
- nocturnal, persists despite fasting
- microscopic colitis, stimulant laxatives; Senna
Osmotic description of diarrhea
- related to intake
- osmotic laxative; Miralax, Olestra
Functional description of diarrhea
- hypermotility, improves with fasting
- Irritable bowel syndrome
Fatty types of diarrhea
Malabsorption, Maldigestion
Malabsorption description of diarrhea
- bloating, gas, steatorrhea
- giardiasis, celiac disease
Maldigestion description of diarrhea
- loss of digestive function; meat fibers
- chronic pancreatitis, cystic fibrosis
Inflammatory types of diarrhea
IBD, Invasive, Neoplasia
IBD description of diarrhea
- white blood cells, pus, blood
- Ulcerative colitis, Crohn’s disease
Neoplasia description of diarrhea
- associated weight loss, abdominal pain
- colon carcinoma
Neoplasia description of diarrhea
- associated weight loss, abdominal pain
- colon carcinoma
Acute infectious diarrhea
- 20 to 30 BM/day
- up to 20 liters of stool per day
Diarrhea reflects an increase in what?
Water
Reasons for increased water in stool from?
- Increased intestinal secretion of water
2. Decreased intestinal reabsorption of water
Differentiate diarrhea from
- Pseudodiarrhea
- Fecal incontinence
- Overflow incontinence
Acute diarrhea duration
-
Protozoa of the colon
-E.histolytica
Chronic diarrhea
> 30days
Watery types of diarrhea
Secretory, Osmotic, Functional
Secretory description of diarrhea
- nocturnal, persists despite fasting
- microscopic colitis, stimulant laxatives; Senna
Osmotic description of diarrhea
- related to intake
- osmotic laxative; Miralax, Olestra
Functional description of diarrhea
- hypermotility, improves with fasting
- Irritable bowel syndrome
Fatty types of diarrhea
Malabsorption, Maldigestion
Malabsorption description of diarrhea
- bloating, gas, steatorrhea
- giardiasis, celiac disease
Maldigestion description of diarrhea
- loss of digestive function; meat fibers
- chronic pancreatitis, cystic fibrosis
Inflammatory types of diarrhea
IBD, Invasive, Neoplasia
IBD description of diarrhea
- white blood cells, pus, blood
- Ulcerative colitis, Crohn’s disease
Invasive description of diarrhea
- infectious causes
- Cdiff
Neoplasia description of diarrhea
- associated weight loss, abdominal pain
- colon carcinoma
Causes of acute diarrhea in healthy adults in developed countries
- usually viral
- more severe diarrhea is more likely bacterial
- protozoa are least common causes
Bacteria of the small bowel
-Salmonella, E.coli, C.perfringens, S.aureus, A.hydrophila, B.cereus, V.cholerae
Virus of the small bowel
-Rotovirus, Norovirus
Protozoa of the small bowel
-Cryptosporidium, Microsporidium, Isospora, Cyclospora, Giardia
Problems resulting in the anus
- anal fissure
- sentinel pile
- fistula
- anorectal ulcers
Virus of the colon
-Cytomegalovirus, adenovirus, herpes simplex
Protozoa of the colon
-E.histolytica
Stuff that results in dysentery
-salmonella, E.coli, campylobacter, shigella, E.histolytica
Stuff that has a preformed toxin
-C.perfringens, S.aureus, B.cereus
Stuff that has an entertoxin
-V.cholerae
Stuff that has an enteroadherent
-Giardia
Stuff that has a cytotoxin
-C.difficile, E.coli 0157
Review three slides with tables
Go to packet
History of diarrhea
- Onset…..of abnormal bowel movements
- Frequency
- Presence….of blood, mucus
- Awoken…in the night for BM
- Associated….symptoms
- Exposures
- Antibiotic…use recently
Bristol stool chart Type 1
Separate hard lumps, like nuts
Description of C.difficile
- toxin mediated colitis caused by overgrowth of C diff in colon
- pseudomembranous colitis
Bristol stool chart Type 3
Like a sausage but with cracks on the surface
Bristol stool chart Type 4
Like a sausage or snake, smooth and soft
Bristol stool chart Type 5
Soft blobs with clear-cut edges
Bristol stool chart Type 6
Fluffy pieces with ragged edges, a mushy stool
Bristol stool chart Type 7
Watery, no solid pieces. Entirely liquid
Physical exam
- vital signs
- general
- abdominal exam
- musculoskeletal
- skin
- rectal exam
Muscles surrounding the anus and rectum
- pelvic floor muscle
- internal anal sphincter
- external anal sphincter
Problems resulting in the anus
- anal fissure
- sentinel pile
- fistula
- anorectal ulcers
Role of testing in acute diarrhea
- routine stool culture
- ova/parasites
- endoscopy
Role of testing in acute diarrhea for ova/parasites
- persistant diarrhea
- persistant diarrhea following travel to Russia, Nepal
- persistant diarrhea with exposure to infants in daycare centers
- diarrhea in a man MSM or AIDS
- a community waterborne outbreak
- blood diarrhea with few or no fecal leukocytes
Oral rehydration
0.5 tsp salt
0.5 tsp baking soda
4 tblsp sugar
Per liter of water
Symptomatic Therapy
- Anti motility agents
- loperamide(Imodium)
- Diphenoxylate(Lomotil)
- Bismuth subsalicylate(Pepto-bismol)
Probiotics
-Align, Culturelle
Dietary alterations
- avoid dairy(temporary loss of lactase)
- low residue diet(white foods, cooked vegetables, low fat meats)
Empiric antibiotics
- fluoroquinolone
- metronidazole
Description of C.perfringens
- enterotoxin produced by bacteria in small intestine
- acute gastroenteritis symptoms
Description of C.botulinum
- paralytic neurotoxin formed by bacteria present in anaerobic environment
- weakness, diplopia, progresses to paralysis
Description of C.tetani
- excitatory neurotoxin formed by bacteria present in wounds
- “lockjaw”
Description of C.difficile
- toxin mediated colitis caused by overgrowth of C diff in colon
- pseudomembranous colitis