Diagnostic testing Flashcards

1
Q

Symptomology

Symptoms are associated with near visual tasks

asthenopia symptoms

  • Headaches
  • Eye strain/fatigue
  • Blurred vision
  • Diplipia
  • Loss of place while reading
  • Diff sustaining near tasks
  • Avoiding near tasks
A

Headaches

  • Location = brow region, frontal
  • Aggravated = by sustained near visual tasks
  • Worse at end of the day
  • NO nausea/vomiting a - more migraine related, neurologically associated

Eye strain/fatigue

  • Tired, droopy lids

Blurred vision (ACCOMODATIVE PROBLEM)

  • Near to Far vice-versa
  • Delay/latency in accommodative system
    • perceived as blur by the patient
    • Common symptom of accommodative dysfunction
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2
Q

Symptoms are associated with near visual tasks

asthenopia symptoms

  • Headaches
  • Eye strain/fatigue
  • Blurred vision (ACCOMODATIVE PROBLEM)
  • Diplipia (VERGENCE PROBLEM)
  • Loss of place while reading
  • Diff sustaining near tasks
  • Avoiding near tasks
A

DIPLOPIA = vergence problems

  • Onset sudden (weeks) or gradual (months)
    • Pts with heterophoric vergence issues will have double vision problems that are GRADUAL
  • Monocular or binocular true double vision is binocular
  • Causes of monocular double vision:
    • Astigmatism
    • Dry eye
    • Media opacity/cataracts
  • Constant or intermittent
    • Constant = progressive problem, strabismic
    • Intermittent = unable to manage phoria problems
  • Distance or near
    • Depends on underlying condition
    • more frequent at distance or near
  • Horizontal vs vertical
    • Horizontal double vision is = convergence/divergence issues
    • Oblique double vision = both horizontal and vertical components - oblique EOMs dysfunction

• Beware: sudden onset double vision associated with nausea, vomiting, loss of balance, headaches, tingling of extremities

frequently associated with neurological type double vision - Needs to be referred for imaging

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3
Q

Symptoms are associated with near visual tasks

asthenopia symptoms

  • Headaches
  • Eye strain/fatigue
  • Blurred vision (ACCOMODATIVE PROBLEM)
  • Diplipia (VERGENCE PROBLEM)
  • Loss of place while reading (SACCADIC DYSFUNCTION)
  • Diff sustaining near tasks
  • Avoiding near tasks
A

Loss of place while reading

  • use finger on the page as they read
  • Reading laborious and frustrating
  • Common in patients with oculomotor problems (i.e. saccadic dysfunction)

Difficulty sustaining near tasks

  • Pt reports frequent breaks in between tasks

Avoiding near tasks

  • No Symptoms because Px avoiding reading
  • Decreased academic performance
  • Usually presents later on in the exam

Abnormal exophoria at near but pt does not report any difficulty reading = they may be avoiding reading

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4
Q

Symptom Questionares

CISS

Convergence Insufficiency Symptom Survey (CISS)​

A

Convergence Insufficiency Symptom Survey (CISS)

  • Validated questionnaire
  • Score is tabulated based on f_requency of symptoms_
    • Higher score = more frequent symptoms = additional testing
    • Lower score = less symptoms § Validity:
  • Not valid for children under 9

Kids (9-18)

  • Normal binocular vision(NBV)score = 8.4 ± 6.4
  • Convergence insufficiency (CI) score = 30.8 ± 8.4
  • CISS ≥16 = Requires additional testing

Young adults (19-30)

  • NBVscore =11 ± 8.2
  • CI score = 37.3 ± 9.3
  • CISS ≥ 21 = Requires additional testing
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5
Q

Symptom Questionares

Brain Injury Vision Symptoms Survey (BIVSS)

Concussion Patients

A

Concussion patients

  • Visual symptoms 30-85% of TBI pts
    • Asthenopia
    • Difficulty with motion perception UNIQUE to head trauma patients
      • Walking into supermarket is arduous (supermarket syndrome) § Due to optic flow problems
      • As you walk down an aisle, peripheral visual information contains NOISE and makes it difficult to process
      • i.e. trouble following a moving object (will make them dizzy) o May see stationary objects as moving
    • Peripheral awareness difficulty
      • ignore objects in periphery
      • Patients would prefer looking at objects with less noise (i.e. blank backgrounds)
    • Issues with depth perception
      • visual-spatial imbalance
    • Light sensitivity very common in head trauma patients
      • Will ask you to turn lights down and slow down talking
      • Treated with filters

Brain Injury Vision Symptoms Survey (BIVSS)

  • Validated in patients with self-reported mild traumatic brain injury (mTBI)
  • More detailed than CISS
  • Score ≥ 31 is suggestive of TBI like symptoms
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6
Q

Systemic Patient history

Dyslexia

ADHD (link to symptomatic CI)

A

Dyslexia

  • Accommodative, vergence, and oculomotor deficits were more prevalent in children with developmental dyslexia
  • Association, NOT causation

ADHD

  • Children with symptomatic convergence insufficiency** + **ADHD = reduced academic performance
  • Ask about asthenopia with near work
  • Headaches
  • Eyestrain
  • Ask about history of concussion!àif so, administer symptom questionnaire
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7
Q
  1. Ocular alignment and AC/A ratio
  2. Tests of accommodation:
    • Amplitude § Dynamics § Response
  3. Tests of eye movements:
    • Pursuits § Saccades
  4. Sensorimotor status:
    • Stereopsis § Worth 4 dot test
  5. Tests of vergence
    • Amplitude § Dynamics
  6. Fixation disparity
A

Prerequisite to testing

  1. Determination of refractive error (static retinoscopy or autorefraction)
  2. MPMVA refraction
  3. Cycloplegic evaluation (1% cyclopentolate x2 5min apart)
    1. first-time pediatric patients
    2. Latent hyperopia!
    3. Adults with wavering refractions/possibility or an overminused prescription
    4. If objective and subjective findings do not match

o Tropicamide better for older kids and adults

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8
Q

Ocular alignment

  • Cover test
  • Modified Thorington
  • Von Graefe

AC/A ratio testing

  • Gradient AC/A
  • Calculated AC/A
A

Ocular alignment

  • Cover test - _w/ accommodative targe_t
    • Document magnitude + direction of phoria at distance and near
  • Modified Thorington MOST RELIABLE METHOD, free space technique
  • Von Graefe
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9
Q

Ocular alignment

Cover test
Modified Thorington
Von Graefe
AC/A ratio testing

Gradient AC/A
Calculated AC/A

Calculated >>Gradient Why?

A

AC/A ratio testing:

  • change in accommodative convergence when accommodation changesby 1D
  • Important for determining final diagnosis and appropriate treatment sequence

Examples: Convergence excess is a high AC/A ratio

  • ESO > N than D
  • Treatment - Added plus lenses work extremely well

Convergence insufficiency is a low AC/A

  • EXO > N than D
  • Treatment - Does NOT respond well with added lenses
  • Should work with prisms and vision therapy

Two methods of testing:

  1. Gradient AC/A
    • Von Graefe or Modified Thorington at 40cm
    • repeat test at same distance using -1.00D lenses OU
    • -1.00 lenses stimulate accommodative convergence § AC/A = change in phoria measurement/lens power
  2. Calculated AC/A
    • AC/A = IPD (cm) + NWD (m) (Phn –Phd)
      • Phn = near phoria (eso = plus, exo = minus)
      • Phd = distance phoria (eso = plus, exo = minus)
  3. Expected value (norms) = 4:1 – 6:1
    • High AC/A > 7:1
    • Low AC/A < 3:1

  • Rule of thumb = high AC/A means MORE ESO or LESS EXO at Near

Calculated AC/A >> Gradient AC/A (why)

  • Proximal vergence = the near phoria measured for calculated AC/A will be impacted by proximal vergence (more eso or less exo)
  • In gradient AC/A phoria is measured TWICE at same distance but with different lenses, so proximal vergence is held constant
  • Shifts in direction of eso
  • Lag of accommodation = we generally underaccommodate for a given accommodate stimulus
    • Since -1.00 is typically used for gradient AC/A, the accommodative convergence triggered is LESS than expectedàthis may cause the gradient AC/A to be LOWER than calculated
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10
Q

Sensorimotor tests:

  • non-strabismic conditions (heterophoria), the ability to maintain fusion and depth perception
  • Important tests to determine prognosis and sequence of treatment

3 types of fusion:

  1. Superimposition (simultaneous fusion) - 1st degree
  2. Flat fusion - 2nd degree
    • W4D tests this
  3. Stereopsis fusion - 3rd degree
    • Global and contour (local) stereopsis
A

Stereopsis

  • Global and contour (local) stereopsis
    • Global = no monocular cues (True stereo RANDOT)
    • Local = monocular cues present
      • not high quality but still tests for stereopsis in pts with limited stereopsis
      • Start with global testing
    • ​ <60 arc sec = peripheral stereoàcoarse stereo

Worth four dot (W4D)

  • Test distance and near
  • Near W4D tests peripheral fusion due to the large area of retina the image subtends
    • significant XP, if they have good peripheral fusion, they will be able to fuse the W4D images • 40cm
  • Distance W4D tests central fusion due to the small area of retina the image subtends • 20 feet

4 balls normal second-degree fusion

  • Normal correspondence (retinal image falls on both foveas)
  • Depth of suppression evaluated by adjusting room illumination
    • Normal room illuminationàtest natural viewing conditions
    • Dim room illuminationàdifficult to maintain suppression in unnatural viewing conditions

If suppression is reported with room lights off, then it is DEEP ROOTED

SUPPRESSION in strabismic patients

Not indicated if you do not suspect suppression

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11
Q

Tests of accommodation

  • Done with best subjective correction
  • Evaluate each aspect of accommodation

Amplitude = measures maximum amount of accommodation stimulated for a given stimulus (in one direction)

Facility = measures ability to stimulate and relax accommodation repeatedly for a given stimulus (more dynamic)

A

Amplitude:

  • Push-up
    • overestimation by 2D - dt Relative dist magnification
  • Pull Away
    • Young children
  • Minus lens to blur
    • Monocular
    • 2D less ant Push up

Facility

  • MAF
    • Tests only accomodative facility
  • BAF
    • Tests accommodation and vergence dynamics keep image clear + single
    • Plus - ability to relax
    • Minus - ability to stimulate
  • Higher amount of cycles better facility
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12
Q

Accomodation Tests

Amplitude

Push up

Pull away

Minus lens to blur

A

AMPLITUDE of ACC

  • Push up
    • with 7A in free space
    • Concerns:
      • Relative distance magnificatio - as the target is moved closer, it is magnified in the retina
      • Overestimation of amplitude by 2D

Norms - Hofsetter’s Formula

  • Avg amplitude = 18.5 – 0.3(age)
  • Min. amplitude = 15 – 0.25(age)
  • Pull away.
  • with 7A free space
  • technique in young children (non-seeing to seeing)
  • upper lid lash - pull the target away until first noticed clear
  • Minus lens to blur
  • 7A phoropter - Done monocularly
  • Procedure:
    • Add -0.25D until first sustained blur
    • Test distance 33cm
    • Correction factor Add 2.50D (accounts for minification due to minus lenses)
      • i.e. pt reports blur at 8th click (2D)àAmp = 2D + 2.50D = 4.50D § Norm:
  • 2D less than that for push-up
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13
Q

Accomodation Tests

Facility

Measures ability to stimulate and relax accommodation repeatedly for a given stimulus o Lens flipper is utilized to test the dynamics

§ Plus lenses = evaluates ability to relax accommodation

§ Minus lenses = evaluates the ability to stimulate accommodation

MAF

asseses ONLY Accomodative Facility

BAF

Asseses Accomodative and Vergence Facility

A

Facility

  • Plus to minus = 1 cycle (1min test)
  • The higher number of cycles, the better the accommodative facility

Monocular Accommodative Facility (MAF)

  • Only tests accommodative facility
  • Diff plus lens = difficulty relaxing accommodation
  • Diff minus lens = difficulty stimulating accommodation

Binocular Accommodative Facility (BAF)

  • Tests accommodation and vergence dynamics = keep image clear + single
  • Plus lens side = behave as base OUT prisms
    • Relaxes accommodation
    • Positive fusional vergence required to maintain binocularity (convergence)
  • Minus lens side = behave as base IN prisms
    • Stimulates accommodation
    • Negative fusional vergence is required to maintain binocularity (divergence)
  • Efficient to start with BAF, if fails, do MAF

• BAF is good screener test (determines if problem is with accommodation or vergence)

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14
Q

Accomadative facility

MAF & BAF

test and rational

A
  • Test setup:
    • 40 cm test distance
    • Accommodative target 2 lines above BCVA
    • Vertical line
    • 7A / Age of pt: 0-30 +/- 2.00 flipper / Test distance 40 cm
    • > 30 years - Scaled Facility
      • based on pt’s amplitude of accommodation
  • Binocular test first, if abnormal then do monocular testing
  • Rationale:
  • BAF - assess accommodation and vergence
    • if normal, likely normal facility
    • Fails lenses in BAF = accommodative or vergence problem
  • Fails BAF but passes MAF = vergence problem
  • Fails BAF and MAF = likely accommodation problem

Testing procedure:

  • Start with + side
  • Instructions: letters clear and single as quick as possible
    • Single not appropriate for MAF
  • What to observe:
  1. ​​Is one lens easier than the other?
    • Accommodative insufficiency (AI) patients have difficulty with minus lens
  2. Is one eye better than the other? (monocular test)
    • Accommodation should be steady and equal to both eyes - anisometropic amblyopia exeption
  3. could not clear one side? (>5 sec to clear for each lens)
    • If more than 5 sec, just flip to other side
    • half a cycle does not count as cpm
      • Record results as = 0 cpm, fails (-) lens OR 0 cpm, fails (+) lens
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15
Q

BAF - Scaled accomadative Facility

Amplitude scaled facility (>30 years)
For determining flipper lens power § Binocular procedure

A
  • PUSH UP - binocular amplitude of accommodation.
  • 45% of that dioptric value as the TEST DISTANCE
    • Convert to cm and round to nearest 0.5 cm
  • 30% of that dioptric value as the lens flipper RANGE
    • Round to nearest 0.25D
    • The flipper power used = range/2

Example: 20D amplitude

  1. 45 (20) = 9D = 11 cm test distance
  2. 30 (20) = 6D / 6D/2 = + 3.00 flippers
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16
Q

Accommodative Response:

Assessment of accuracy of accommodative response to a stimulus - At 40cm, the accommodative demand is 2.5D

Norm = slight accommodative lag

Objective assessment:

Monocular Estimation Method (MEM)

Nott retinoscopy

Book Reinoscopy

A

Monocular Estimation Method (MEM) retinoscopy

  • very reliable
  • Used when prescribing Near ADD
  • Working distance:
    • Adults habitual reading distance
    • Children Harmon distance (distance from elbow to middle knuckle)
  • Age-appropriate cards
  • Ret the amount of plus or minus to neutralize
    • With motion (WM) = lag of accommodation (+)
    • Against motion (AM) = lead of accommodation (-)
      • Always abnormal / dont neutralize

Normal value = +0.50 + 0.25D, range of + 0.25D to +0.75D slight lag of accommodation

  • If pt’s lag = +1.50 pt is UNDERACCOMMODATING by more than 0.75D for that distance
  • Use +1.50 or +1.00 lens as add, check for change in accommodation / new scope should only be +0.50D
  • Lenses are used in 2 ways:
  1. Measuring lenses loose lenses < 1⁄4 of a second to NOT stimulate accommodation
  2. Probe lenses flippers - long enough to induce accommodation

Examples:

  1. Neutrality/plano in OD, with-motion in OS
  • Plano is bordering a LEAD in accommodation, not normal
  • Could be due to
    • Anisometropia
    • uncorrected astigmatism in one eye
    • incorrect binocular balance

Plano in OD, against-motion in OS

  • Both eyes are showing a lead response
  • Caused:
    • over-minus
    • uncorrected astigmatism in one eye
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17
Q

Assessment of accuracy of accommodative response to a stimulus - At 40cm, the accommodative demand is 2.5D

Norm = slight accommodative lag

Objective assessment:

Monocular Estimation Method (MEM)

Nott retinoscopy

Book Reinoscopy

A

Nott retinoscopy

  • very reliable
  • Response measured without lenses
  • changes dist space to determine neutrality
  • Patients selection: sensitive around their face, do not like trial frames/lenses, being touched, Down’s syndrome, sensory system overload, etc.
  • Target remains at test distance
    • If “with motion” detected - MOVE AWAY till neutral
  • The dioptric difference in space between the PATIENT to TARGET and the PATIENT to SCOPE represents the lag of accommodation
  • Distance neutrality is obtained (in diopters) = accommodative response (AR)
  • Distance of target (in diopters) = accommodative stimulus (AS)
  • Lag of accommodation = AS – AR
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18
Q

Assessment of accuracy of accommodative response to a stimulus - At 40cm, the accommodative demand is 2.5D

Norm = slight accommodative lag

Objective assessment:

Monocular Estimation Method (MEM)

Nott retinoscopy

Book Reinoscopy

(NOTT + MEM ret most acurate for Lag)

A
  • *Book retinoscopy**
  • *QUALITY of response** as pt is presented with a reading material
  • Grade response based on COLOR of reflex
  • patient reads for comprehension - appropriate material is obtained, probe lenses are used
  • As accommodation increases: Reflex against-motion

Stage 1 = Free Reading (IDEAL)
Pt comprehension with little effort
o Reflex is BRIGHT (whitish-pink) and is neutral to low with-motion (WM)
Close to neutrality, fast streak

Stage 2 = Easy Instructional Level
Comprehension with some effort
o Reflex is BRIGHT PINK and essentially neutral with minor shifts to WM and AM

Stage 3 = Difficult Instructional Level
hard to maintain/achieve comprehension
o Reflex is DARK REDDISH PINK and is fluctuating AM (-0.25D to -1.25D)

Stage 4 = Nonreading/complete frustration level
Comprehension not possible
o Reflex is DULL BRICK RED and has high with-motion HEAVY LAG o Also seen if no effort is put forth regardless of demand

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19
Q

Tests of Vergence:

Amplitude measures range of amount of convergence/divergence pt is able to exert

Dynamic measures fluidity of moving from convergence to divergence
Measures the change in vergence direction within a specific amount of time uses prisms

Amplitude:

NPC

Step / Smooth vergence

Dynamics

Near vergence Facility

Dist vergence Facility

A

Near Point of Convergence (NPC)

maximum convergence amount - Recommended: two measures

  • Accommodative target – Burnell fixation stick
    • Norms = 5cm/7cm
    • Emphasis on break, not blur
    • Start where target is CLEAR AND SINGLE
    • Monitor for suppression OBJECTIVE result
  • Penlight and red/green glasses
    • Norms = 7cm/10cm
    • OD - red light, OS - green light
    • adds stress to the disparity vergence system general to keep the target single

Red/green glasses intentionally adds stress to the system to see if NPC recedes

Difference in norms are especially evident in patients with CI

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20
Q

Tests of Vergence:

Amplitude measures range of amount of convergence/divergence pt is able to exert

Dynamic measures fluidity of moving from convergence to divergence
Measures the change in vergence direction within a specific amount of time uses prisms

Amplitude:

NPC

Step / Smooth vergence

Dynamics

Near vergence Facility

Dist vergence Facility

A

Step/smooth vergence
Measures vergence range (convergence and divergence) using prism bars or prisms in phoropter
Done at distance and near

  • Step vergence
    • Free space, allows us to monitor the eyes with increasing prism
    • No blur value
  • Smooth vergence
    • phoropter
    • CT findings are normal - use this technique
    • Norms are different = are physiologically different tests
  • Smooth vergence = smoothly and slowly increase vergence demand
  • Step vergenc indiscrete increases in vergence demand (not the same size steps)

If performed one method pre-treatment, USE same for post-treatment evaluation

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21
Q

Tests of Vergence:

Amplitude measures range of amount of convergence/divergence pt is able to exert

Dynamic measures fluidity of moving from convergence to divergence
Measures the change in vergence direction within a specific amount of time uses prisms

Amplitude:

NPC

Step / Smooth vergence

Dynamics

Near vergence Facility

Dist vergence Facility

A

Vergence Dynamics:

  • Near vergence facility
    • 3BI / 12BO (stacked prism)
      • ​BO ranges are generally larger than BI ranges
    • Binocular test @ 40 cm
    • Target = single column of 20/30 letters
    • Start with Base In prism
    • shown to differentiate between symptomatic vs non-symptomatic patients
    • Norm=15cpm+3cpm
      • 12 cpm means abnormal
      • trouble clearing ONE SIDE of the prism
      • Decline over time
  • Distance vergence facility
    • sensitive measure in CI and concussion patients
    • Also helpful in conditions such as divergence excess
    • Norm=15cpm+3cpm

Summary of vergence tests:
- In a busy primary care practice, consider:
o NPC
o Near vergence facilit
y
differentiate symptomatic from asymptomatic patients

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22
Q

Tests of Eye movements:

Pursuits, Saccades, Fixation

  • Loss of placement during reading, skipping or omitting lines/words, using their finger to guide during reading
  • indicate a saccadic or pursuit dysfunction

saccadic dysfunction - HATE reading - task of reading is difficult and tedious

  • Direct observation of eye movement
    • Northeastern State University College of Optometry (NSUCO)/Maples test
  • Visual-Verbal
    • Developmental Eye movement test (DEM)
    • King-Devick test
  • Objective eye movement recordings
    • ​Visagraph
    • Right eye
A

NSUCO (Maples Test):

  • Components assessed:
    • Saccades / Pursuits / Head movement / Body movement
  • Developmentally - do not exhibit eye movements without head or body movements
  • Ages: 5 years and above
  • Test distance: Harmon distance / no farther than 40cm
  • Set up: patient stands directly in front of the examiner
    • No instruction given on whether or not to move head
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23
Q

NSUCO (Maples test)

NSUCO Saccades

NSUCO Pursuits:

NSUCO scoring criteria:

A
  • NSUCO saccades:
    • 2 targets, 20 cm apart
    • Binocular - Horizontal Saccades
    • Wolff wands or different colored pens
    • Instruction: only look at the color instructed to.
    • Pause maintaining fixation on the target - assess fixation
    • 5 round trips
  • NSUCO Pursuits:
    • Pursuit = follow One target
    • Two clockwise rotations and two counterclockwise rotations
    • 20 cm diameter circular path
    • Instruction: Don’t ever take your eyes off it”
  • NSUCO scoring criteria:
    • Ability to perform the task - Accuracy of performance
    • Saccades = overshoots or undershoots
    • More over/undershoot - less accurate the accuracy score
    • Eye movements in isolation - HEAD still - High score
  • *Overshoot** = eyes initially go past target, needs to refixate
  • *Undershoot** = eyes lag in front of the target, have to make corrective saccade to target

But there seems to be more head and body movements when we are younger
o Less and less head and body movements as we age, around 10-11 years of age
- Eye movements are not very accurate at young agesàlevel off at 10-11 years of age

24
Q

Eye Movement tests Visual-Verbal tests:

  • Simulation of a reading environment
  • Calling out numbers = verbal component of test
  • Reading the numbers = visual component of test
  • *eye movement problem or difficulty naming numbers?**

DEM:

o DEM test can distinguish if the patient has a number naming problem vs an eye movement problem

  • Normed for 6-14 years old - peds test, can use in adults who have suffered a head injury too
A

DEM

  • Diff reading the numbers in the vertical columns (cards A and B) AND the horizontal rows (card C)àit is a number naming difficulty
  • perfect vertical columns (cards A and B)Diff reading horizontal rows (card C) it is an eye movement problem

Errors

  • Omission omits a few numbers or entire rows
  • Addition numbers added or repeated
  • Substitution numbers read incorrectly and not immediately
  • Transposition numbers called out of sequence

Setup

  • If > 3 errors are noted in the vertical portion = repeat ONCE MORE
  • If >3 errors persist, STOP testing further
  • Compute
    • Total vertical time
    • Horizontal adjusted time
      • Adjusted time = Time x [80/(80 – omission + addition)
    • Total errors
      • Total errors = (s+o+a+t)
      • _entire line omitte_d is counted as 1 for TOTAL ERRORS
    • Ratio
      • Horizontal Adjusted time / Vertical time
    • ​Errors:
      • entire line is skipped, count those 5 omitted numbers as 5 when using the formula for adjusted time
      • _entire line omitte_d is counted as 1 for TOTAL ERRORS
  • If pt has symptoms use 0.5 SD
  • If pt is Asymptomatic use 1.5 SD
25
Q

DEM

Interpretation of results

A
  • Type I = normal
    • Pt has normal number naming ability and eye tracking ability
  • Type II saccadic dysfunction
    • Pt has normal number naming ability but eye tracking has significant issue
  • Type III. automaticity (number naming difficulty)
    • Pt has normal eye tracking ability
    • vertical and horizontal components, the time will be HIGH for BOTH
  • Type IV combo of type II and type III
    • Pt has number naming issues and saccadic dysfunction
26
Q

Eye Movement testing

King-Devick test:

  • 3 test plates containing lines of numbers

**This test fails to control for automaticity**

A

King-Devick test:

  • 3 test plates containing lines of numbers
  • fast and accurate as possible - Each test plate is timed
  • TOTAL time compared to norms
  • ## **This test fails to control for automaticity**

Uses:

  • Increasingly used as a sideline screening tool for concussion
  • Eye movement screening in Parkinson’s, Alzheimer’s etc.
  • DEM has more clinical value
27
Q

Objective Eye movement recorders:

Uses infrared eye tracking system

Visagraph/Readalyzer

RightEye

A
  • Visagraph/Readalyzer
    • Horizontal/vertical saccades (maybe pursuits)
  • RightEye
    • Pursuits, saccades
    • Pt sits 50cm from the screen

Benefits:

  • Sophisticated measures
    • Fixation
    • Duration of fixation
    • Regression
    • Reading rate
  • Not dependent on examiner skills
  • Gives both graphical and quantitative results

Disadvantages:

  • COST
  • Difficult to use in inattentive/hyperactive patients
28
Q

Fixation Disparity:

  • Failure to maintain targets on both fovea but still have fusion (within fusional area)

Slight vergence slip but still binocular

A

Fixation Disparity:

  • Evaluates binocular vision under associated conditions
  • Helpful for determining prism Rx = does not overestimate!
  • Not part of routine exam, don’t perform on every single patient

Clinical tests:

o Saladdin card

o Wesson card

29
Q

Types of Accommodative dysfunction:

  • Duke-Elder classification
  • Accommodative insufficiency
    • Ill-sustained accommodation
  • Accommodative infacility
    • Paralysis of accommodation
  • Spasm of accommodation (excess)
A

Accommodative insufficiency

  • Difficulty in stimulating accommodation
  • Key signs:

  1. Amplitude - reduced amplitude of accommodation
    • < 2D less Hofstetter’s minimum or more
  2. Response - High lag (> +0.75D) on MEM
  3. Facility - Difficulty clearing -2.00 flippers on MAF (minus lenses stimulate accommodation)

Accommodative infacility

  • difficulty changing the accommodative response level
  • Latency and speed of response (dynamics) are abnormal
  • Key signs:

  1. Amplitude - Normal
  2. Response - Normal (i.e. MEM will be normal)
  3. Facility - Difficulty clearing BOTH (+) and (–) lenses on MAF KEY DIAGNOSITC SIGN

Accommodation (excess)

  • Difficulty with relaxing accommodation
  • Accommodative response is greater than stimulus
  • Key signs:

  1. Amplitude - Normal
  2. Response - Low MEM (will get plano or (-) / LEAD of accom
  3. Facility - Difficulty clearing (+) lenses on MAF
30
Q

Accommodative insufficiency (AI):

  • Difficulty in stimulating accommodation
  • Key signs:

  1. Amplitude - reduced amplitude of accommodation
    • < 2D less Hofstetter’s minimum or more
  2. Response - High lag (> +0.75D) on MEM
  3. Facility - Difficulty clearing -2.00 flippers on MAF (minus lenses stimulate accommodation)
  4. Supporting signs:
    • BAF Difficulty with -2.00D flippers binocularly
    • Reduced PRA

TREATMENT (preferred) - Visual therapy for AI

A

Treatment:

  1. Vision Therapy for AI
    • ​Preferred treatment to normalize accommodative amplitude
    • Added plus lenses are NOT preferre - DOES NOT improve symptoms
    • 12-14 in-office visits with home reinforcementà~3-3.5 month treatment​
  2. Correction of refractive error
    • Small hyperopia/astigmatism/anisometropia > 1.00 should prescribe 7A
    • Cycloplegic evaluation
    • ATR and oblique astigmatism lower thresholds for refractive correction (Pt Might need -0.50 comfort)
  3. Added plus lenses (aka near ADD or near vision spectacles)
    • Does NOT rectify the insufficient amplitude
      • symptomatic if NVO are stopped - Passive treatment
    • Considerations:
      • krutch - VT to mitigate symptoms
      • Pt refuses vision therapy

How to prescribe? Added plus lenses

  • MEM
    • Determine plus needed to bring the value down to normal lag (+0.50 to +0.75D)
    • repeating MEM with tentative ADD

MEM: OD +1.25D, OS +1.25D = Possible near adds: +0.50 or +0.75

  • NRA/PRA
31
Q

Accommodative infacility:

  • Patient experience difficulty changing the accommodative response level
  • Latency and speed of response (dynamics) are abnormal
  • NOTE - Normal amplitudes - If only AA or response is measured but not facility, infacility can easily be missed
  • Key signs:
  1. Amplitude - Normal
  2. Response Normal (i.e. MEM will be normal)
  3. Facility - Difficulty clearing BOTH (+) and (–) lenses on MAF
  4. Supporting sings:
    • Difficulty with (+) and (–) lenses on BAF
    • Reduced NRA/PRA (narrow range)
A

Neither added lenses NOR prisms will be of any benefit to accommodative infacility

Treatment

  1. Correction of refractive error
    • ​​Head trauma Pts benefit more from Small 7A
    • Small hyperopia/astigmatism/anisometropia
  2. Vision therapy
32
Q

Accommodative excess (AE):

  • Difficulty with relaxing accommodation
  • Accommodative response is greater than stimulus
  • AKA
    • Spasm of the near reflex - miosis, convergence, accommodation
    • accommodative spasm
    • pseudo-myopia
  • Key signs:
  1. Amplitude Normal
  2. Response - Low MEM (will get plano or (-) - LEAD of accom
    • ​​_West Coas_t = LEAD of accom = against motion or (-) value on MEM • So plano would NOT be considered a LEAD of accom
    • East Coast = LEAD of accom = plano and anything less than plano
  3. Facility - Difficulty clearing (+) lenses on MAF
  4. Supporting signs:
    1. Difficulty clearing + lenses on BAF
    2. Low NRA

Pt will report first sustained blur very QUICKLY on NRA b/c they are unable to relax their accommodation with higher plus lenses

A

Treatment

  1. Correction of refractive error
    • Small hyperopia/astigmatism/anisometropia
  2. Vision therapy
    • Added lenses and prisms do NOT help accommodative excess
33
Q

DDX

Accommodative Insufficiency

Accommodative Infacility

A

Non-functional causes to rule out AI or Accommodative infacility

  • Drugs
    • Alcohol
    • Antihistamines
    • Phenothiazides
    • Cycloplegics
    • CNS stimulants
    • Marijuana
  • Diseases – adults
    • DM
    • Anemia
    • MS
    • Botulism
    • Myotonic dystrophy
    • Malaria
    • Typhoid
  • Eye diseases – adults
    • Iridocyclitis
    • Glaucoma
    • Iris sphincter tear
    • Blunt trauma
    • Scleritis
  • Diseases – children
    • Anemia
    • Mumps
    • Measles
    • Tonsilitis
    • Whooping cough
    • Lead/arsenic poisoning
34
Q

DDX

Accommodative Excess

A

Non-functional causes to rule out AE

  • Drugs
    • Cholinergic drugs
    • Morphine
    • Sulfonamides/CAI
  • Diseases – adults
    • Encephalitis
    • Syphilis
    • Trigeminal neuralgia
  • Diseases – children
    • Encephalitis
    • Meningitis
    • Influenza
35
Q

Summary table

Accommodative Dysfunctions

A
36
Q

Ocular Motor Dysfunction:

  • Ocular motor control clinically develops more SLOWLY than accommodative and vergence systems
  • Basic research data à normal levels by 1-2 years of age
  • Clinical research data = development continues through elementary school (mostly end of third grade)
  • Eye movements are thought to be related to higher cognitive processes (attention, memory, visual processing)

TYPES:

A

Types of ocular motor dysfunction:

  1. Pathological
    • ​​Disease
    • Trauma
    • Drugs
  2. Functional
    • Accommodative and/or vergence dysfunction
    • Actual non-path OMD
    • Role of attention and cognition
    • Relationship to school and sports
      • Eye movements in reading
      • Eye movements in sports
  3. Developmental
37
Q

Persuits and Saccadic

Pathways

A

Pursuits

  • Control centers of pursuits is believed to be the occipitoparietal junction
  • Supranuclear control of pursuits are ipsilateral
  • Occipitoparietal junction. – midbrain – nuclei of the EOMs

Saccades

  • Control centers of saccades originate in the frontal eye fields (Brodmann’s area 8)
  • Supranuclear control of saccades are contralateral
  • Frontal eye fields – midbrain pons – nuclei of the EOMs
38
Q

Differential diagnosis of Pursuit dysfunctions:

  • Serious underlying disease to rule out:

Cogwheeling

Slow pursuit gain

A
  • Differential diagnosis of Pursuit dysfunctions:
  • Serious underlying disease to rule out:
  • Cogwheeling (step-like/staccato movement)
    • Possible causes:
      • Basal ganglia disease
      • Parkinson’s disease – caused by dopamine deficiency, leads to impaired neural inhibition
        • Signs:
          • Muscle rigidity
          • Slowness of movements
          • Tremors
      • Cerebellar disease
  • Slow pursuit gain
    • Aging
    • Tranquilizers
    • Anticonvulsants
39
Q

Differential diagnoses of Saccadic dysfunction

  • Disorders of velocity
  • Disorders of accuracy
  • Disorders of initiation
  • Inappropriate saccades
A

Differential diagnoses of Saccadic dysfunction:

  • Disorders of velocity
    • Saccades too slow
      • Ocular motor nerve paresis
      • Internuclear ophthalmoplegia
    • Saccades too fast
      • Internuclear ophthalmoplegia
    • Truncated saccades (shortened in duration/extent)
      • Myasthenia gravis
  • Disorders of accuracy
    • Dysmetria – over or under shooting
  • Disorders of initiation
    • Reaction time differences
  • Inappropriate saccades
    • Interfere with foveal fixation
    • Saccadic intrusion syndrome
40
Q

CASE Ddx

Found nystagmus in superior gaze during EOMs

  • Ask about headaches, nausea, dizziness, diplopia, tingling arms and legs, change in appetite, unintended weight gain/lossàneurological questions
  • Further neurological testing:
    • Cover test, Color vision, Fields, DFE o Were all negative

multiple sclerosis
Blurry vision, nystagmus, optic neuritis were the presenting signs of MS

A

Dx: saccadic intrusion syndrome secondary to her acquired brain injury

  • Inappropriate saccades that disrupts fixation
  • Prescribed Gabapentin (aka Neurontin, for anti-seizure, diabetic neuropathy, control of migraines, overall used in a lot of neurological incidences) with no relief
  • jumping of the target in all positions with a decrease in superior gaze
  • High velocity spontaneous horizontal saccadic intrusions were observable in all positions of gaze with a decrease in superior direction

Largest improvement was reported and observed while wearing plano with 6pd yoked BD prism OU

41
Q

Drug effect on eye Movement

A
42
Q

Developmental OMD:

  • Patient with overall delay of development
  • Birth history
  • Prenatal
    • History as an infant
    • Environment
    • Nutrition
  • Prematurity
  • Perinatal
  • Unknown
A

Craniosynostosis - Abnormal head development due to premature closure of seams in skull

Crouzon syndrome - - most common, premature fusion of skull bones
Can turn down lights so less distracting for stimulus to gauge eye movements

43
Q

Symptoms Associated with OMD

A
  • Loss of place of omission of words when reading
  • Skipping lines
  • Difficulty copying from the blackboard
  • Poor comprehension
  • Slow reading speed
  • Poor attention, easily distractible
  • Fatigue when reading
  • Vertigo, dizziness
  • Motion sickness
  • Poor performance in sports
  • Excessive head movement
  • ASK ABOUT USING FINGER TO GUIDE WHILE READING!!
44
Q

Muscle actions

Primary - Secondary - Tertiary

A
45
Q

Eye movements:

Pursuits

to maintain a moving object on the fovea

A

Pursuits = to maintain a moving object on the fovea

  • Significant role in sports and driving
  • Not as much associated with reading

Fixation = to evaluate the ability of the patient to maintain steady fixation

  • Measure of EOM control as well as attention
  • Duration of fixation on a piece of information ~ 200-250 ms
  • Children learning to read and poor readers tend to make more and longer fixations
  • Abnormal fixation results in square wave intrusion – due to lack of EOM control
46
Q

Saccadic eye movements:
To bring an off-foveal object onto the fovea

A

Saccadic eye movements:

  • To bring an off-foveal object onto the fovea @ 10% of reading time
  • Average saccade is 8-9 characters (can range 2-15 characters)
  • Duration of the saccade is a function of the distance covered
  • Between saccades, the eye is relatively still in fixational pause
  • The perfect saccade is a single eye movement that rapidly reaches and abruptly stops at the target of interest

Inaccuracies:

  • Undershooting - most common
    • Stops just before the target
    • Eyes either then glide towards the target or make another saccade to reach target
  • Overshooting - less common
    • Eyes go past the target, have to come back
47
Q

Regressions

Right-left eye movement (backtracking)

  • the reader overshoots the target
  • misinterprets the test
  • has difficulty with comprehension of reading material

Children with reading or learning difficulties have high prevalence of eye movement anomalies

A
  • *Regressions:** - Right-left eye movement (backtracking)
  • Can occur when the reader overshoots the target, misinterprets the test, or has difficulty with comprehension of reading material
  • Increases as difficulty of reading material increases
  • Normal readers
    • 10-20% of all saccades during reading are regressions
  • Poor readers
    • 35-40% of all saccades during reading are regressions
  • Objective methods are most accurate to measure regressions
    • Readalyzer

o But hard to separate cause and result
o Important to ask about SCHOOL HISTORY!

i.e. is your child reading on grade level? Any difficulty reading? Are they receiving any additional educational resources? à determined if there any types of learning difficulty that the doctor should look into further

48
Q

Classification: Vergence Anomalies

3 main categories based on AC/A ratio:

  1. Low AC/A ratio
    • Convergence insufficiency
    • Divergence insufficiency
  2. Normal AC/A ratio
    • Basic exophoria
    • Basic esophoria
    • Fusional vergence dysfunction
  3. High AC/A ratio
    • Convergence excess
    • Divergence excess
A

Modified Duane’s Classification:
Is phoria greater at distance or near?

  • N > D = convergence problem
    • ESO = high AC/ = CE
    • EXO = low AC/A = CI
  • D > N = divergence problem
    • ESO = low AC/A = DI
    • EXO = high AC/A = DE
  • D = N = basic
    • ESO = normal AC/A = basic eso
    • EXO = normal AC/A = basic exo
    • Normal AC/A = fusional vergence dysfunction

Phorias may be normal, need to look at other conditions

49
Q

Phorias

Also evaluate the Qaulity / Type instead of only the Magnitude

A
  • Phorias at D and N = look for magnitude difference but ALSO quality/type of deviation

EXAMPLE:

  • CT at distance–8XP , CT at near – 6IXT
  • If you just look at the numbers, it seems that distance is worse than near = would assume basic EXO
  • But if you look at the quality as well, the patient has worse control of their deviation at near (b/c intermittent exotropia) than at distance (latent phoria)

CI b/c deviation is worse at near than distance

50
Q

Low AC/A Conditions:

Convergence insufficiency

Divergence insuficiency

A

Convergence insufficiency (CI)

  • Key signs:
    • EXO Near > Distance
    • Receded NPC
    • Low AC/A
    • Low PFV at near
    • Difficulty with BO on vergence facility
      • BO demands convergence
  • Supporting signs:
    • Difficulty clearing (+) on BAF
      • (+) lenses trigger accom relaxation and PFV
    • Low MEM = LEAD of accom
      • Pts with convergence problems (low PFV) often have to rely on their accommodative vergence to focus at near More accommodation = lead of accom
      • Low NRA (+ lenses)
51
Q

Convergence insufficiency (CI)

+

Accommodative Dysfunctions

A

Convergence Insufficiency

  • CI + A-Excess
    • Difficulty with (+) on MAF testing
  • CI + A-Insufficiency
    • Difficulty with (-) on MAF testing
    • Low amps
    • Possible improvement in NPC with plus lenses at near
52
Q

Convergence insufficiency (CI)

TYPES

A

Types:

  • True CI
  • Pseudo CI
    • Underlying accommodative insufficiency leading to reduced accommodative effort and greater exophoria at near
    • CI can be secondary to AI
    • Mild improvement in NPC with plus lenses

53
Q

Convergence Insufficiency

Treatment

A

Treatment:

True CI

  1. Correct refractive error
    • Hyperopia consideration - significant hyperopia may wish to correct it EVEN if the EXO gets worse
  2. Prisms (base-in) Relieving Prisms
    • Relieves the demand on fusional vergence (convergence)
    • Amount determined by:
      • Sheard’s criterion
      • Fixation disparity
  3. Vision therapy = preferred treatment of choice (both young pts and adults

Pseudo CI

  1. Plus lenses at near
  2. VT as needed

§ **Correct any PRIMARY vertical deviation**

  • A primary vertical deviation exists even under fused conditions (binocular), as a fixation disparity
  • Secondary deviations manifest when pt is dissociated = don’t have to treat because it disappears when patient is fusing

True for ALL VERGENCE ANOMALIES

  • An uncorrected vertical deviation can impede the treatment of horizontal deviations
  • The compensating fusional skills are different in horizontal and vertical deviations
54
Q

Prescribing Prism

SHEARDS Criterion

A

Near cover test - 16 XP’

Near Base OUT - x/16/10 - always use Blur value unless not measured

Sheard’s:

Amount of Prism = 2/3(phoria) - 1/3(compensating fusional vergence)

= 0.66(16) - 0.33(16)

=5.3 BI

55
Q
A