Diagnostic pathology of cancer Flashcards
Define dysplasia
a loss of uniformity of individual cells and architecture
Define hypoplasia
The underdevelopment or incomplete growth of an organ
Define atrophy
adaptive response where there is a decrease in size and function of cells
Hypertrophy
adaptive response where there is an overdevelopment of an organ with increase in number of cells
hyperplasia
converse of hypoplasia- overdevelopment of an organ with an increase in number of cells
Metaplasia
Transformation of one differentiated cell type to another differentiated one
How would you predict prognosis of a patient with invasive carcinoma of the breast?
Look at vascular invasion, also notingham prognostic index gives prognosis by combining invasive grade, lymph node stage andinvasive tumour size