Diagnosis & Management Flashcards
What are the common causes of constipation?
- Simple constipation – poor diet (especially fibre), low fluid intake, reduced mobility, drugs
- Specific condition/presentation - IBS, pregnancy, elderly
What are the 5 red flags for constipation?
- Anaemia
- Loss of weight
- Anorexia
- Recent onset (sudden change)
- Melaena (blood in stools)
What are the 4 referral symptoms for constipation?
- Treatment failure
- Suspected faecal impaction
- Suspected anal fissure/fistula/undiagnosed haemorrhoids
- Any symptoms that sit outside of your area of competence
What is first line treatment for constipation?
- lifestyle advice (water, diet)
What is recommended order of the 3 laxatives?
- bulk-forming (not to be taken if caused by meds)
- osmotic
- stimulant (firstline for opioid)
How do bulk forming laxatives work?
- Mimic increased fibre intake, which swells in the bowel and increases faecal mass. They also promote the proliferation of faecal bacteria
- Must be accompanied by increased fluid intake
- Slower to work and can take up to 72 hours for effect to be seen
- Side effects include bloating and abdominal distension
How do osmotic laxatives work?
- They act to retain fluid in the bowel by osmosis
- Take up to 48hrs to see effect
- Side effects include flatulence and cramps
- Requires lots of water
How do stimulant laxatives work?
- Increase GI activity by directly stimulating colonic nerves
- Quick acting – generally seeing an effect within 6-12 hours
- The main side effect seen is abdominal pain
- Should be avoided in pregnancy
How do stool softeners work?
- Docusate is the most commonly used and is a non-ionic surfactant that allows penetration of water into the faecal mass
- They also have weak stimulant properties
- Do not supply or recommend liquid paraffin
What is the new safety advice for stimulant laxatives?
- now a third line treatment
- max pack size of 20 for GSL
- age restricted to 18+
- P sale to 12-17s, under 12s to GP
What are the 4 common causes of acute diarrhoea?
- Bacteria
- Viruses
- Protozoa
- Drugs
What are the 8 referral symptoms for diarrhoea?
- Blood/mucus in stools
- Dehydration/associated vomiting (tiredness, weakness)
- Weight loss
- Recent hospital stay or use of antibiotics
- Diarrhoea following recent foreign travel
- Failed treatment
- Symptoms lasting > 2-3 days in children and elderly (24 hours in diabetics)
- Medicine induced diarrhoea
What is the first priority of diarrhoea treatment?
oral rehydration therapy containing glucose, sodium chloride, potassium chloride and disodium hydrogen citrate
available in different flavours
What are the 2 anti-motility drugs and how do they work?
Loperamide - works by acting on mu-opiate receptors to increase the tone of both the small and large bowel, hence increasing intestinal transit time and reabsorption
Bismuth subsalicylate (Pepto-Bismol) – more traditional treatment which remains popular by some – thought to improve symptoms but less effective than loperamide
What advice is given to patients with diarrhoea?
- Drink plenty of clear fluids
- Avoid very sugary drinks
- Avoid milky drinks
- Eat depending on appetite, consider avoiding if exacerbates diarrhoea
- Avoid contact with food till better/stay off work
- Careful hygiene
What are the 3 common causes of haemorrhoids?
- Constipation and straining
- Family history
- pregnancy
What are the 3 common symptoms of haemorrhoids?
- Blood on stools/toilet paper
- Pain on defecation
- Itching
What are the 7 referral symptoms for haemorrhoids?
- First presentation
- Blood in stools
- Patients who have to reduce haemorrhoids manually–3rd or 4th degree haemorrhoids
- Severe pain/stabbing/sharp pain associated with defecation
- Rectal symptoms with associated signs of infection
- Symptoms that don’t resolve within 7 days/get worse with treatment
- Any symptoms that sit outside of your area of competence
What are the 4 degrees of haemorrhoids?
1st degree – project into the lumen but don’t prolapse
2nd degree – prolapse on straining but return to the lumen spontaneously
3rd degree – prolapse on straining and must be returned manually
4th degree – prolapsed and cannot be returned to the anal canal
What are the treatments for haemorrhoids?
- Dietary changes – essential for all patients to reduce straining and resolve the possible cause. Consider a bulk forming laxative if needed or address constipation
- Local anaesthetics (Lidocaine) – temporary relief from pain and itching
- Astringents (eg bismuth, zinc) – coats the haemorrhoids to provide a protective layer
Anti-inflammatories (eg hydrocortisone) – reduce inflammation
Protectorants (eg shark liver oil) – forms a protective layer hence relieves pain and associated itching
What is the lifestyle advice for haemorrhoids?
Avoid constipation
Anal hygiene
Don’t ignore the call
Avoid undue straining
Position
What are the 8 common symptoms of IBS?
- Abdominal pain, located especially in the lower left quadrant of the abdomen
- Pain can be relieved by defecation or passage of wind
- Constipation and/or diarrhoea
- Bloating, distension, tension or hardness
- Altered bowel habit
- Symptoms made worse by eating
- Passage of mucus
- Diarrhoea after eating or on waking
What are the red flag symptoms for IBS?
- Unintentional and unexplained weight loss
- Rectal bleeding
- Recent change in bowel habit
- Persistent or frequent bloating in females (especially if aged over 50 years)
- Abdominal or rectal mass
- Symptoms with a family history of bowel cancer, ovarian cancer, coeliac disease, or inflammatory bowel disease.
- Patients with no history of IBD
- Steatorrhoea (extra fat in faeces)
- Any symptoms that sit outside of your area of competence
What are the 4 treatments for IBS?
Antispasmodics
- Hyoscine – Buscopan
- Mebeverine – Colofac IBS
- Peppermint oil – Colpermin IBS
Laxatives can be recommended (ispaghula), but lactulose should be discouraged
Anti-diarrhoeals – loperamide first line
Probiotics