Diagnosis Flashcards

1
Q

What is diagnosis based on?

A

Typical clinical features supported by spirometry

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2
Q

Can you treat the patient with a SABA before investigations begin?

A

Yes

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3
Q

When would you suspect COPD based on symptoms?

A

> 35yrs with a risk factor and one of the following:
• SOB
• Chronic cough
• Regular sputum production
• Frequent lower respiratory tract infections
• Wheeze

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4
Q

What are the other symptoms associated with COPD?

A
  • Winter exacerbations
  • Weight loss, anorexia and fatigue
  • Waking at night with breathlessness
  • Ankle oedema
  • Reduced exercise tolerance
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5
Q

What would you look for on examination?

A

Hands:
• Tar-staining of fingers

Face:
• Central cyanosis (if hypoxic or polycythaemia)

Chest:
•	Tachypnoea
•	Hyper-inflated chest (barrel-shape)
•	Use of accessory muscles 
•	Reduced lateral and increased vertical chest expansion
•	Paradoxical lower chest motion
•	Reduces breath sounds
•	Polyphonic expiratory wheeze
•	Palpable liver edge
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6
Q

What spirometry results would show a restrictive lung disease?

A

FEV1 <80% predicted

FVC <80% predicted

FEV1/FVC >70% normal

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7
Q

What do normal spirometry results show?

A

FEV1 >80% predicted

FVC >80% predicted

FEV1/FVC 75-80%

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8
Q

What spirometry results would show a obstructive lung disease?

A

FEV1 <80% predicted

FVC normal or low

FEV1/FVC <70% normal

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9
Q

What is GOLD stage 1?

A

FEV1 ≥ 80% of predicted value

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10
Q

What is GOLD stage 2?

A

FEV1 > 50-79% of predicted value

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11
Q

What is GOLD stage 3?

A

FEV1 < 30-49% of predicted value

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12
Q

What is GOLD stage 4?

A

FEV1 ≤30% of predicted value or FEV1 <50% with respiratory failure

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13
Q

What are the signs of cor pulmonale?

A
  • Peripheral oedema
  • Raised JVP
  • Systolic parasternal heave
  • A loud pulmonary second heart sound
  • Hepatomegaly
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14
Q

What is cor pulomale?

A

Hypoxia -> pulmonary artery constriction -> increased pulmonary artery pressure -> RV hypertrophy -> RV failure

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15
Q

What other investigations would you order for COPD?

A
  • CXR

- FBC

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16
Q

What is the purpose of a CXR?

A
  • May be normal
  • May show hyperexpansion and low, flat hemidiaphragms
  • Excludes lung cancer, bronchiectasis, TB and HF
17
Q

What other investigations could you do depending on the situation?

A
  • Sputum culture
  • ECG
  • CT scan
  • PEF measurements
  • Serum alpha1-antitrypsin
18
Q

What do PEF measurements exclude?

A

Asthma

19
Q

What does an ECG exclude?

A
  • IHD
  • Arrhythmias
  • Right-sided heart strain