Diabetic neuropathy

Question 1

What type of neurological deficit does diabetic neuropathy typically lead

Answer 1

Sensory loss and not motor peripheral neuropathy

Question 2

First line treatment for diabetic neuropathy

Answer 2

Amitriptyline
Duloxetine
Gabapentin or prcegablin

Tramadol may be used as rescue therapy in exacerbations

Question 3

Other agents for management of neuropathic pain

Answer 3

Topical capsaicin may be used for localised neuropathic pain

Question 4

What is gastroparesis

Answer 4

AKA delayed gastric emptying is a disorder that slows or stops movement of food from stomach into small intestine

Question 5

Symptoms of gastroparesis

Answer 5

Erratic blood glucose control
Bloating
Vomiting

Question 6

Management of gastroparesis

Answer 6

Metoclopramide

Domperidone or erythromycin(prokinetic agents)

Question 7

Definition of hypoglycaemia

Answer 7

defined as a plasma glucose level of 3 mmol/L or less

Question 8

Common causes of hypoglycaemia in a non-diabetic patient(EXPLAIN)

Answer 8

Exogenous drugs such alcohol, aspirin poisoning, pentamidine, quinine sulfate, ACE-inhibitor

Pituitary insufficiency
Liver failure
Addison's disease
Islet cell tumours eg insulinoma
Non-pancreatic neoplasms