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Pharmocology > Diabetic medications > Flashcards

Diabetic medications Flashcards

1
Q

Glicazide, Glimepride

Sulfonylureas MoA

A

binds to ATP-dependent potassium channels and decrease potassium efflux out of the pancreatic beta-cells.
This stimulates insulin secretion by the Beta-cells

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2
Q

Metformin

Biguanides MoA

A
  1. Complex-1 inhibitor
    accumulation of AMP and activation of AMP kinase which can restrict gluconeogenesis
  2. Increase peripheral glucose uptake/increase insulin sensitivity
  3. Decrease GI glucose absorption
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3
Q
A
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Pharmocology (4 decks)

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