Diabetes Pharma

Question 1

Januvia: generic name, DM drug class, doses

Answer 1

Sitagliptin, DPP-IV inhibitor (incretin enhancer), dose is 100mg daily.

Question 2

What are the major classes of DM drugs by MOA?

Answer 2

1) Alpha glucosidase inhibtors
2) Biguanides
3) DPP-IV inhibitors (incretin enhancers)
4) GLP-1 receptor antagonists
5) SGLT2 inhibitors
6) sulfonylureas
7) Thiazolinediones
8) insulin

Question 3

What is the difference between glumetza and metformin?

Answer 3

Glumetza is an extended release form of metformin that lasts 24 hrs and has a max dose of 1000 mg.

Question 4

Janumet: generic name, DM drug class, dose

Answer 4

sitagliptin/metformin, DPP-IV/biguanide, max dose 100mg/2g PO daily (split BID or OD if extended release)

Question 5

Jentadueto: generic name, DM drug class, dose

Answer 5

Linagliptin/metformin, DPP-IV/biguanide, max 5mg/2g PO (split BID or OD if ER)

Question 6

Trajenta: generic name, DM drug class, dose

Answer 6

Linagliptin, DPP-IV inhibitor, 5mg PO daily

Question 7

Victoza: generic name, DM drug class, dose

Answer 7

Liraglutide, GLP-1 receptor agonist, up to 1.8 mg SQ daily

Question 8

Forxiga: generic name, DM drug class, dose

Answer 8

dapagliflozin, SGLT-2 inhibitor, max 10 mg PO daily

Question 9

Jardiance: generic name, DM drug class, dose

Answer 9

Empagliflozin, SGLT-2 inhibitor, max 25 mg PO daily

Question 10

Diamicron: generic, class, dose

Answer 10

Gliclazide, sulfonylurea, max dose IR 320 PO daily, MR 120 PO daily

Question 11

Basaglar: generic, class, duration

Answer 11

Glargine biosimilar, basal insulin, 18-26 hrs

Question 12

Levemir: generic, class, duration

Answer 12

Detemir, basal insulin, 16-24 hrs

Question 13

Lantus: generic, class duration

Answer 13

Glargine, basal insulin, 18-26 hrs

Question 14

Humulin: class, duration

Answer 14

basal insulin, up to 18 hrs

Question 15

Novolin: class, duration,

Answer 15

NPH, basal, up to 18 hrs

Question 16

Tresiba: generic, class, duration

Answer 16

degludec, basal insulin, up to 42 hrs

Question 17

Toujeo: generic, class, duration

Answer 17

Glargine U300, basal concentrated, >30 hrs

Question 18

Humalog: generic, class, duration

Answer 18

Lispro, bolus insulin, 3-5 hrs

Question 19

Humulin-R: generic, class, duration, time before meal

Answer 19

Insulin Regular, Toronto, bolus insulin, lasts 6.5 hrs, administer 30 min before meal.

Question 20

Novorapid: generic, class, duration, time before meal

Answer 20

Aspart, insulin bolus, duration 3.5 hrs, give 10-15 min before food.

Question 21

Name 3 qWeekly DM meds

Answer 21

Trulicity (dulaglutide), exenatide (bydureon), semaglutide (ozempic)