Diabetes Mellitus

Question 1

Pathophysiology of type I DM

Answer 1

autoimmune destruction of pancreatic beta cells - insufficient insulin produced

Question 2

Pathophysiology of type II DM

Answer 2

developed resistance to insulin

Question 3

General presentation of DM

Answer 3

polyuria
polydipsia
lethargy
pruritis vulvae (increased risk of candida)
recurrent/prolonged infections

Question 4

What are the blood glucose readings diagnostic of diabetes?

Answer 4

random >11 mmol/L

fasting >7 mmol/L

Question 5

What are the HbA1c readings for (pre-)diabetic?

Answer 5

42-47 mmol/L = prediabetic

>48 mmol/L = diabetic

Question 6

What microvascular complications are patients with DM at risk of?

Answer 6

nephropathy, neuropathy, retinopathy