DIABETES MELLITUS Flashcards
a metabolic disorder or disease that is brought about by either the insufficient production of insulin or inadequate activity of insulin
receptors.
Diabetes mellitus
The disease can be classified into three different categories:
the type 1,
type 2 and gestational diabetes
Type I or Type II:
partial or absolute deficiency of
endogenous insulin production and require exogenous insulin for survival
Type I
Type I or Type II:
(c) Characterized by:
1) Polyuria / Polydipsia
2) Weight loss
3) Plasma glucose of 126 mg/dL or higher after an overnight fast, documented on more than one occasion.
4) Ketonemia / ketonuria - inadequate insulin leads to inadequate glucose
within muscle cells which promotes fat metabolism (the source of ketones).
Type I
Type I or Type II:
Most patients are over 40 years of age and obese, though is becoming more
common in adolescence.
Type II
Type I or Type II:
Polyuria and polydipsia. Ketonuria and weight loss generally are uncommon
at time of diagnosis. Candidal vaginitis in women may be an initial
manifestation. Many patients have few or no symptoms.
Type II
Type I or Type II:
(c) Plasma glucose of 126 mg/dL or higher after an overnight fast on more
than one occasion.
(d) Random glucose of 200mg/dL or higher.
(e) Hemoglobin A1C of 6.5% or higher.
Type II
Type I or Type II:
Hypertension, dyslipidemia, and atherosclerosis are often associated.
Type II