Diabetes medications

Question 1

Which DM drug class has the highest risk of hypoglycemia
Why do we not want to give this to some elderly?

Answer 1

Sulfonyureas
WHOMEVER IS A FALL RISK

Question 2

Sulfonyureas
Meds

Answer 2

Glipizide
Glimepiride (Amaryl)
Chlorpropamide

Question 3

Concerned about which organs in TZDs?

Answer 3

Cardiac and hepatic (heart and liver)
Cardiotoxicity - BIG NO NO IN HF d/t weight gain + fluid retention
Hepatotoxicity

Question 4

TZDs
meds

Answer 4

Pioglitazone
Rosglitazone

Question 5

Which two drug classes are cardio-protective and decrease overall CV risk?

Answer 5

SGLT2 inhibitots +
GLP-1 agonists

Question 6

Which drug class do you not prescribe to elderly with urine incontinence or those prone to UTIs?

Answer 6

SGLT2s inhibitors
- They excrete glucose in urine

Question 7

Which DM med is an injection

Answer 7

GLP-1 agonists
- do not give to needle fearing ppl

Question 8

Which DM class is contraindicated in those with thyroid cancer or pancreatitis

Answer 8

GLP-1 agonists

Question 9

Preferred tx for gestational diabetes

Answer 9

NO ORAL
ONLY DO INSULIN B/C doesn’t cross placental barrier

Question 10

Which drug category is the cheapest option?

Answer 10

Sulfonylureas
Metformin too

Question 11

Which DM meds cause weight gain?

Answer 11

TZDs and Sulfonylureas

Question 12

SGLT2 inhibitor
meds

Answer 12

Empagliflozin
Cangliflozin
Dapagliflozin

Question 13

GLP-1 agonists
meds

Answer 13

Duaglutide
Semaglutide
Liraglutide
Exenatide