Diabetes medication Flashcards
1
Q
Sulfonylurea MOA
A
stimulate release of insulin from pancreatic beta cells
2
Q
DDP-4 inhibitors
A
increase incretins by decreasing peripheral breakdown
3
Q
DDP-4 examples
A
-Gliptin
4
Q
DDP-4 side effects
A
pancreatitis
UTI
GI
5
Q
DDP-4 monitoring
A
on initiation: kidney, liver function
3 monthly LFTs first year
6
Q
GLP-1 MOA
A
increase incretins -> stimulate insulin secretion
7
Q
GLP-1 Side effects
A
WEIGHT LOSS
acute pancreatitis
nausea and vomiting
8
Q
GLP-1 Monitoring
A
HbA1c >11mmol/mol
3% weight loss
9
Q
GLP-1 indications
A
BMI >35
BMI <35 but weight loss would benefit co-morbidities
10
Q
GLP-1 examples
A
-tide
liraglutide
exanatide
