Diabetes drugs

Question 1

Dapagliflozin drug class?

Answer 1

SGLT2 inhibitor

Question 2

Pioglitazone drug class

Answer 2

TZDs

Question 3

Names of DPP4 inhibitors

Answer 3

‘gliptins’

sitagliptin

Question 4

Names of SGLT2 inhibitors

Answer 4

‘flozins’

dapagiflozin, canagiflozin

Question 5

Indications for starting SGLT2 inhibitors 1st line at the same time at metformin

Answer 5

established CVD, CHF, or Qrisk score >10%

Question 6

Sulphonylurea drug classes

Answer 6

Gliclazide

Question 7

Name of GLP1 mimetic drug

Answer 7

Semiglutide

Question 8

MoA of GLP1 mimetics

Answer 8

stimulate release of insulin

Question 9

MoA of DDP4 inhibitors

Answer 9

incream levels of GLP1 and GIP which in turn stimulate the release of insulin

Question 10

Metformin side effects

Answer 10

GI upset
Lactic acidosis

Question 11

Suphonylurea side effects

Answer 11

hypos
Increased appetite and weight gain

Question 12

Pioglitazone side effects

Answer 12

fluid retention
fractures
weight gain

Question 13

goal HbA1C (depending on whether they are on hypoglycaemics or not)

Answer 13

53 is they’re on hypoglycaemics,
48 if they are not

Question 14

When to consider adding metformin in pts with T1DM

Answer 14

BMI >25

Question 15

sulphonylureas MoA

Answer 15

increase secretion of insulin by pancreatic beta cells

Question 16

diabetes drug contraindicated in current or previous bladder cancer?

Answer 16

Pioglitazone