Diabetes care in hospital Flashcards

1
Q

What is diabetes

A

Its a metabolic condition characterised by a state of persistant hyperglycaemia. as a result of inulin deficiency, insulin resistance or some combination of both

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2
Q

Why do we all need insulin in our bodies?

A
  • insulin the key to permitting cellular glucose uptake and reducing hepatic glucose output - LIVER
  • insulin also promotes the cellular uptake of potassium
  • also has an anabolic role
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3
Q

History taking: Key factors include?

A

Diabetes type (1,2 or 3) & duration

Are you known to have any damage to the body due to diabetes?

Diabetes treatments: tablets? insulin? both? times, doses, insulin pump? Who administers medications?

Does the patient check glucose levels at home? especially at home

Smoking, Alcohol intake, Fluid intake, Bowel habit

Visual problems?

Foot problems: changes in colour, shape, swelling, pain, discharge?

Are they aware of having any low sugar episodes (hypoglycaemic episodes), awareness + frequency?

Do you drive? always check sugar levels before you drive - UK legal requirement.

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4
Q

Physical examination: Clinical findings of note

A
  • Blind patient
  • A stroke patient
  • Ketones on breath (sweet breath from ketoacidosis, unwell)
  • Body surface areas - abscess, acanthosis nigricans
  • A patient with renal disease: Fistula/dialysis
  • An amputee or bandaged lower limbs (must check under bandages)
  • Leg swelling (heart failure, immobile, dependent oedema due to gravity, kidney problems or liver disease)
  • Lipohypertrophy (repeated insulin jabs in the same place cause lumps)
  • Wearable diabetes tech (eg a ‘flash’ glucose meter measures skin fluid glucose but blood), (an insulin pump in type 1 diabetes patients , or a continuous glucose monitoring device)
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5
Q

Useful investigations

A

Ensure bedside blood glucose monitoring is in place

  • Hba1c (from within last 6 months ideally) - broadly aiming for 48-58 mmol/mol where possible (nb frail and elderly)
  • eGFR
  • BP
  • weight (often recorded on admission)

treatment plan - always consider diabetes related factors and start discharge planning early

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6
Q

Types of diabetes:

A

Type 1 (have particular vigilance, this patient makes absolutely no insulin at all)

Type 2

Type 3 (pancreatic diabetes types)

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7
Q

A plea for type 1 D

A
  • People with Type 1 diabetes need insulin in bodies at ALL times
  • Will hopefully be carbohydrate counting - so they can adjust their insulin to what they’re eating (menu carbohydrate available on ward?)
  • S/C injections: usually 2 times daily ‘Fixed Mix’ or ‘Basal Bolus’ regimens
  • CSII (personal pump) - disconnect and use IV insulin if patient cannot self manage
  • Respect the patient voice (concerns, anxieties etc)
  • vomiting!!! = DKA until proved otherwise
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8
Q

Vomiting is the first sign of?

A

impending Diabetic Keto Acidosis - until proven otherwise

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9
Q

In the UK, risk of keto acidosis is?

A

1 in 25

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10
Q

Acute illness + diabetes points:

A

Stress of acute operations or health problems (eg sepsis) can destabilise diabetes

Interventions can upset diabetes control:
- eg steroids, feeds, fasting, reduced mobility, incorrect prescribing, delayed diabetes medicines administration

Need to communicate effects of interventions on diabetes to the patient where relevant

Diabetes problems can cause non-specific symptoms:
- vomiting or short of breath = DKA?
- confusion/drowsiness = hypoglycaemia, HHS, foot sepsis?
- see R.E.D

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11
Q

Remember Emergencies in Diabetes: R.E.D

A
  • Diabetic KetoAcidosis (DKA)
  • Hyperosmolar Hyperglycaemic State (HHS)
  • Hypogylcaemia
  • Uncontrolled hyperglycaemia
  • Active Diabetic Foot disease
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12
Q

For any unwell patient (with or without diabetes) what score do we use?

A

ABCDE (NEWS2)

don’t ever forget glucose
- ABCDEFG

if levels are too high or low, appropriate action should be taken promptly

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13
Q

Hyperglycaemia can increase length of stay and delay clinical recovery by:

A

hyperglycaemia can suppress the immune system by 90% and delay clinical recovery from acute illness and sepsis

Can also delay wound healing after surgery - risky state to ignore

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14
Q

Aim for blood glucose?

A

Level 5-12mmol/L in hospital

BGM issues: ‘obs stable’ is WRONG

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15
Q

When would you suspect a ward patient has hyperglycaemia?

A

Sustained BGL > 15 more than 3-4 hrs

context? new problem? usual diabetes control

Type 1 diabetes? check ketones +/- VBG to exclude DKA

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16
Q

Glucose High = Why & Dry

A

CauseS include:

  • Suboptimal prescribing or medication dose adjustment
  • States of diabetes emergency (eg DKA, HHS)
  • Sepsis (foot disease?)
  • Sedentary
  • Suspected new diabetes diagnosis
  • Steroids
  • Supplements (feeds)
  • State of mind… (eating wrong footd, not taking medication etc)

Not just a ‘stat’ dose of rapid acting insulin please!
Its great to hydrate

17
Q

What about hypoglycaemia?

A

BGL < 4 mmol/L

Medical emergency

18
Q

9 Rs of hypoglyaemia?

A
  • Recognise
  • Respond (ward hypo kit)
  • Reflect (cause?)
  • Record & handover
  • Reassess, but don’t omit post hypo insulin if due
  • Renal (if insulin clearance is reduced it could cause hypoglycaemia?)
  • Reduce risk (therapies/doses ok? Leaflets, driving)
  • Refer?
  • Responsibility?
19
Q

Not eating & drinking?

A

NMB (for surgery), vomiting etc

might need to use IV insulin infusion, if they’re not having food or drink they MUST be given some glucose based fluids to act as a substrate for the insulin

  • should be monitored every hour or 2
20
Q

Stop the DAMN druGS : drugs that should be questioned:

A

Diuretics
Antihypertensives
Metformin
NSAIDs
GLP-1s
SGLT-2 inhibitors

Review diabetes meds - suspend/reduce? usually being taken?

21
Q

When someone is unwell, dehydration with evidence of poor tissue perfusion: which drugs are considered risky if continued?

A

Metformin (suspended if unwell, due to risk of causing lactic acidosis)

Sulphonylurea (eg Gliclazide): if patient can’t eat properly suspend otherwise hypoglycaemia

SGLT2 inhibitors (‘flozins’: DNA signal (suspend if unwell))

GLP-1 injectables (‘atides’) - work by causing reduced GI transit so should be suspended if unwell to reduce risk of vomiting for example

Don’t forget Insulin - Dose may need reviewing to increase/decrease however is always continued

22
Q

Key safety points:

A

Safe prescribing ESPECIALLY insulin

  • Safe use of IV insulin (with BGM)
  • Type 1 diabetes care - Never stop insulin
  • SGLT2 inhibitors (DKA risk)
  • Suspend other meds if indicated
  • Focussed foot exam (to exclude active diabetic food disease)
  • Frailty
  • Discharge planning

Never cannulate a patient’s foot who’s diabetic!! if infected can lead to need of amputation

Symptoms & signs - eg SOB, drowsy?

Remember Emergencies in Diabetes (R.E.D)