Diabetes Flashcards

1
Q

Also known as starch blockers.

A

a-Glucosidase Inhibitors

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2
Q

oral/gel glucose tablets have to be used if hypoglycemia occurs for (drug name)

A

Acarbose (Precose)

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3
Q

Where do starch blockers block the starch?

A

Small bowel

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4
Q

Side effects of a-Glucosidase Inhibitors are:

A

flatulence, cramps, abdominal distention, rumbling bowl sounds, and diarrhea.

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5
Q

Which drug do you not give in the arm?

A

Amylin Analogs:

pramlintide (Symlin)

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6
Q

Which drug increases insulin synthesis from the pancreas and stimulates GLP-1?

A

Glucagon-Like Peptide Receptor Agonists

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7
Q

Exenatide (Byetta & Bydureon), Liraglutide (Victoza), Albiglutide (Tanzeum), Dulaglutide (Trulicity), and Lixisenatide (Adlyxin). Are:

A

GLP-1 Receptor Agonists.

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8
Q

Advantage of combination Oral Therapy

A

The patient takes fewer pills which leads to better adherence to therapy.

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9
Q

Bromocriptine (Cycloset) is a

A

Dopamine Recepter Agonist.

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10
Q

Hypoglycemia

A

Low blood glucose >70mg/dl

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11
Q

If a patient has dark urine especially then you need to notify physician if pt is taking:

A

Thiazolidinediones
Pioglitaxone (Actos)
rare

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12
Q

Actos side effects:

A

Edema, May raise LDL, No hypoglycemia, Weight gain in combination

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13
Q

How long should you wait to resume metformin after surgery?

A

48 hours.

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14
Q

Side effects of Metformin (Biguanides)

A

Decreased appetite, Nausea, Vomiting, Diarrhea, lactic acidosis (rare).

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15
Q

Which drug increases insulin sensitivity at tissue level

A

Biguanides (Metformin)

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16
Q

Sulfonylureas are:

A

Glipizide (glucotrol/glucotrol XL), Glyburide (DiaBeta, Glynase, Micronase), Glimepride (Amaryl),

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17
Q

Which drug increases insulin release from the pancreas?

A

Sulfonylureas

18
Q

When should you give Sulfonylureas?

A

30 minutes before or with a meal.

19
Q

Dawn phenomenon

A

Blood sugars keeps rising like the sun.

20
Q

Somogyi Effect

A

Blood sugar drops during the night and raises a lot by morning.

21
Q

Problems with Insulin Therapy

A

Allergic reaction, Lipodystrophy, Somogyi, and dawn phenomenon.

22
Q

What gives continuous insulin via SQ?

A

Insulin Pump

23
Q

Where can you inject insulin?

A

Lower back, Tops of Thighs, Belly, Back of arms.

24
Q

Where is the fasted absorption?

A

In the Abdomen

25
Q

Process of mixing insulin?

A

Air Air Clear Cloudy

26
Q

Long duration insulins are:

A

detemir (levemir) last 18-23 hr
Glargine (Lantus) up to 24hr
Degludec (Tresiba) last up to 42 hr.

27
Q

Can you mix long duration insulins?

A

NO!!

28
Q

what is retinopathy?

A

Eye damage/death

29
Q

Intermediate Duration are:

A

NPH (Humulin N, Novolin N

Cloudy 1.5-4 hr onset peak 4-12hr

30
Q

Nephropathy is:

A

Kidneys damage/death

31
Q

Neuropathy:

A

Nerve damage/death

32
Q

Short duration is:

A

regular insulin (Humulin R, Novolin R, ReliOn R)

33
Q

How can you give regular insulin?

A

SQ, IV, IM, IP

The only one that can be given IV or IP.

34
Q

Short action are:

A

Lispro (HUmalog), Aspart (NovoLog), Glulisine (Apidra).

35
Q

What type of insulin should you never give IV?

A

Short action, rapid acting

36
Q

Duration of Rapid acting insulin?

A

Effects begin 15 minutes of SQ peak 30min -3 hours, duration 3 to 5 hours.

37
Q

Can you give short action insulin immediately after meal?

A

Yes.

38
Q

Untreated Hypoglycemia leads to:

A

Loss of conciousness, Seizures, Coma, Death.

39
Q

Macrovascular is:

A

Disease of the large and medium sized blood vessels.

40
Q

Microvascular is:

A

Disease of small blood vessels.

41
Q

Leading cause of Blindness for people ages 20-74 years.

A

Diabetic Retinopathy.

42
Q

Microvascular affects:

A

Retinopathy, Nephropathy, Dermopathy.