Diabetes Flashcards
Dx of Prediabetes?
FPG 100-125
2hr PG = 140-199 after a 75g OGTT
a1c = 5.7-6.4%
Dx of DM?
hyperglyc or hyperglyc crisis + PG > 200
FPG > 126
2hr PG > 200 after a 75g OGTT
a1c > 6.5
How much calories to lose 1 lb a week?
3500 calories in one week
what is the waist circumference goal for females and males?
35 inches for females, 40 inches for males
How many grams of carbs is: one small piece of fruit 1 slice of bread 1/3 cup of cooked rice/pasta 1/2 cup of oatmeal
15 grams
what drugs can increase BG?
BB diuretics cough syrups immunosupressants niacin, statins PI, FQ 2nd gen AP
Who should receive a max dose statin?
Pts with ASCVD risk > 20%
who shoudl receive a medium statin?
age 40-75 years old with risk factors
what are the ADA treatment goals?
a1c < 7%
pre- plasma glgose = 80 - 130
peak postprandial plasma glucose = < 180
what drugs minimize hypoglycemia?
DPP4 inh
GLP1 agonists
SGLT2 inh
TZD
what drugs promote weight loss?
GLP1 agonists or SGLT2 inh
what drugs are the cheapest?
SU or TZD
how many drug tx can u add before initiating insulin?
3 drug therapies before insulin if a1c not at goal < 7
what drugs shuold not be used in HF?
TZD and alogliptin and saxagliptin
which drugs shuold not be used for peripheral neuropathy / diabetic foot ulcers
canagliflozin
which drug should not be used in gastroparesis / GI disorder?
glp1 agonists and pramlintide
which drugs shuold not be used in eGFR or CrCl < 30?
metformin, sglt2i, exenatide, glyburide
which drugs carry risks for pancreatitis?
dpp4i, glp1
which drugs carry risk for cancer?
pioglitazone, dapagliflozin, glp1
what drugs can cause hypoglycemia?
linezolid, BB, pentamadine, FQ
sx of DKA?
mostly in DM1 BG > 250 ketones ph < 7.35 AG > 12
sx of HHS?
mostly in DM2
BG > 600
extreme dehydration
pH > 7.3
tx for hyperglycemic emergencies?
NS until BG reaches 200 then change to d5w 1/2 NS
0.1u/kg bolus then 0.1u/kg/hr CIVI OR 0.14u/kg/hr CIVI
only tx acidosis with bicarb if pH < 6.9
insuline dosing for DM1?
0.5u/TBW
insulin dosing for DM2?
0.1-0.2u/TBW. Only add bolus if a1c not at goal despite control of FBG
TZD moa?
ppary agonists that cause increased peripheral insulin sensitivity?
TZD name?
pioglitazone