Diabetes Flashcards

1
Q

Dx of Prediabetes?

A

FPG 100-125
2hr PG = 140-199 after a 75g OGTT
a1c = 5.7-6.4%

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2
Q

Dx of DM?

A

hyperglyc or hyperglyc crisis + PG > 200
FPG > 126
2hr PG > 200 after a 75g OGTT
a1c > 6.5

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3
Q

How much calories to lose 1 lb a week?

A

3500 calories in one week

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4
Q

what is the waist circumference goal for females and males?

A

35 inches for females, 40 inches for males

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5
Q
How many grams of carbs is:
one small piece of fruit
1 slice of bread
1/3 cup of cooked rice/pasta
1/2 cup of oatmeal
A

15 grams

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6
Q

what drugs can increase BG?

A
BB
diuretics
cough syrups
immunosupressants
niacin, statins
PI, FQ
2nd gen AP
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7
Q

Who should receive a max dose statin?

A

Pts with ASCVD risk > 20%

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8
Q

who shoudl receive a medium statin?

A

age 40-75 years old with risk factors

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9
Q

what are the ADA treatment goals?

A

a1c < 7%
pre- plasma glgose = 80 - 130
peak postprandial plasma glucose = < 180

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10
Q

what drugs minimize hypoglycemia?

A

DPP4 inh
GLP1 agonists
SGLT2 inh
TZD

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11
Q

what drugs promote weight loss?

A

GLP1 agonists or SGLT2 inh

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12
Q

what drugs are the cheapest?

A

SU or TZD

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13
Q

how many drug tx can u add before initiating insulin?

A

3 drug therapies before insulin if a1c not at goal < 7

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14
Q

what drugs shuold not be used in HF?

A

TZD and alogliptin and saxagliptin

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15
Q

which drugs shuold not be used for peripheral neuropathy / diabetic foot ulcers

A

canagliflozin

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16
Q

which drug should not be used in gastroparesis / GI disorder?

A

glp1 agonists and pramlintide

17
Q

which drugs shuold not be used in eGFR or CrCl < 30?

A

metformin, sglt2i, exenatide, glyburide

18
Q

which drugs carry risks for pancreatitis?

A

dpp4i, glp1

19
Q

which drugs carry risk for cancer?

A

pioglitazone, dapagliflozin, glp1

20
Q

what drugs can cause hypoglycemia?

A

linezolid, BB, pentamadine, FQ

21
Q

sx of DKA?

A
mostly in DM1
BG > 250
ketones
ph < 7.35
AG > 12
22
Q

sx of HHS?

A

mostly in DM2
BG > 600
extreme dehydration
pH > 7.3

23
Q

tx for hyperglycemic emergencies?

A

NS until BG reaches 200 then change to d5w 1/2 NS
0.1u/kg bolus then 0.1u/kg/hr CIVI OR 0.14u/kg/hr CIVI
only tx acidosis with bicarb if pH < 6.9

24
Q

insuline dosing for DM1?

A

0.5u/TBW

25
Q

insulin dosing for DM2?

A

0.1-0.2u/TBW. Only add bolus if a1c not at goal despite control of FBG

26
Q

TZD moa?

A

ppary agonists that cause increased peripheral insulin sensitivity?

27
Q

TZD name?

A

pioglitazone