Diabetes Flashcards
In the fasting state, blood glucose is maintained by drawing upon the ______ stores in the ______
Glycogen stores in the liver
Why can’t skeletal muscle directly contribute glucose to the blood?
They lack the enzyme glucose-6-phosphatase
Insulin promotes _____ and ______
Glycogenesis and lipogenesis
Insulin _____ blood glucose levels by…..
Decreases; increasing permeability of the cells to glucose
Where is insulin produced?
Beta cells of the pancreas
Where are growth hormone and ACTH produced?
Anterior pituitary
How do growth hormone and ACTH compare to insulin?
- Antagonistic action to insulin
- tends to raise blood glucose
Where is hydrocortisone produced?
Adrenal CORTEX
Hydrocortisone stimulates what process?
Gluconeogenesis (which will increase blood glucose)
Cushing‘s disease is hyper or hypo adrenalcorticism?
Hyperadrenocorticism
Addison’s disease is hyper or hypo adrenocorticism?
Hypoadrenocorticism (leading to low blood glucose)
Where is epinephrine produced?
Adrenal medulla
What is the function of epinephrine?
Stimulates glycogenolysis with a resultant increase in blood glucose levels
Where is glucagon produced?
- alpha cells of the pancreas
What Is the function of glucagon?
Stimulates hepatic glycogenolysis (which increases blood glucose)
