Diabetes Flashcards
The primary organ involved in diabetes mellitus is the?
Pancreas
What is the abbreviation for hyperosmolar hyperglycemic state?
HHS
Where is the pancreas located?
Behind the stomach between the spleen and the duodenum.
Describe the two functions of the pancreas
1) Acini cells secrete digestive enzymes into the duodenum.
2) the Islets of Langerhans release insulin and glucagon.
What is hyperglycemia?
High blood glucose level
What is hypoglycemia?
Low blood glucose level
What two hormones must be balanced to prevent hypoglycemia and hyperglycemia?
Insulin and glucagon
What cells in the Islets of Langerhans produce insulin?
Beta cells
The primary function of insulin is to
Regulate blood glucose levels
How does insulin regulate blood glucose levels?
Insulin eases the active transport of glucose into muscle and fat cells
Insulin facilitates
Fat formation
Complete the sentence
Insulin inhibits the breakdown and movement of __________ _________
Stored fat
Insulin helps move amino acids into cells for?
Protein synthesis
Glucose unused by the cells stored in the liver and muscle cells are known as
Glycogen
Complete the sentence
If there is excess glucose it is converted into fat and stored as __________ ________
Adipose tissue
When does insulin release increase?
When blood glucose level rise
When does insulin levels decrease?
When blood glucose levels fall
Fill in the blank
When a person eats food, insulin levels rise in minutes, peak in ___ to 60minutes, and return to baseline in _____ to ______ hours
Peak 30-60 minutes, baseline 2-3 hours
What cells in the islets of Langerhans produce glucagon?
Alpha cells
Glucagon prevents blood glucose from?
Decreasing when the body is fasting or between meals
Define gluconeogenesis
When glucagon makes new glucose
Define glycogenolysis
When glucagon converts glycogen into glucose in the liver and muscle
Complete the sentence
Glucagon _______ excess glucose breakdown
Prevents
Complete the sentence
The primary function of glucagon is to _______ glucose oxidation and to ______ blood glucose
Decrease, increase
Glucagon is released when blood glucose falls below
70 mg/dL
Explain what Counter-regulatory hormones are
Hormones that help increase glucose levels.
List some examples of counter regulatory hormones
Epinephrine, growth hormone, and cortisol
Normal blood glucose is maintained in healthy people through a balance of actions between?
Insulin and glucagon
According to SMH and the Burke textbook normal blood glucose is defined as
70 to 110 mg/dL
Refer to Figure 34-3 on page 883 and complete the paragraph.
When there is high blood glucose in the body the pancreas releases _____. This causes the cells to take up _____ from the blood or the liver to produce _______. This allow the blood glucose to fall.
When there is high blood glucose in the body the pancreas releases INSULIN. This causes the cells to take up GLUCOSE from the blood or the liver to produce GLYCOGEN. This allow the blood glucose to fall.
Refer to Figure 34-3 on page 883 and complete the paragraph
When there is low blood glucose the pancreas releases ______ which makes the liver break down __________ causing the blood sugar to rise.
When there is low blood glucose the pancreas releases GLUCAGON which makes the liver break down GLYCOGEN causing the blood sugar to rise.
List the three laboratory tests for the pancreas
Fasting blood glucose, glycosylated hemoglobin (HbA1c), and two hour oral glucose tolerance test (OGTT)
What are the normal values for the glycosylated hemoglobin test? (HbA1c)
5.5% to 7%
What are the normal lab values for the two hour oral glucose tolerance test? (OGTT)
Less than 125mg/dL
What test determines the level of glucose 2 hours after drinking 75g of glucose?
Two hour oral glucose tolerance test (OGTT)
What test is uses to measure glucose control during the previous 3 months and is not used to diagnose diabetes mellitus.
Glycosylated hemoglobin (HbA1c)
What test measures circulating blood glucose levels?
Fasting blood glucose
What laboratory test is done fasting?
Fasting blood glucose
What laboratory test does not require fasting?
HbA1c, glycosylated hemoglobin
What laboratory test requires a client to be NPO for 12 hours before the test then drink entire 100g of glucose and not eat anything else until blood is drawn
Two hour oral glucose tolerance test (OGTT)
Define diabetes mellitus
A common chronic disease of adults due to insufficient supply of insulin, ineffective insulin action or both
Fill in the blank
Depending on the type of diabetes and the client’s age, client _______ and _______ ______ may vary greatly.
Depending on the type of diabetes and the client’s age, client NEEDS and NURSING CARE may vary greatly.
What is the sixth leading cause of death in the United States that has over $134 billion spent on health care?
Diabetes mellitus.
Type 2 diabetes is common in
Older adults African American women Hispanic women Native Americans Asians Pacific Islanders Obesity
True or False
Diabetes mellitus can be cured
False
The primary organ involved in diabetes mellitus is the?
Pancreas
Where is the pancreas located?
Behind the stomach between the spleen and the duodenum.
Describe the two functions of the pancreas
1) Acini cells secrete digestive enzymes into the duodenum.
2) the Islets of Langerhans release insulin and glucagon.
What is hyperglycemia?
High blood glucose level
What is hypoglycemia?
Low blood glucose level
What two hormones must be balanced to prevent hypoglycemia and hyperglycemia?
Insulin and glucagon
What cells in the Islets of Langerhans produce insulin?
Beta cells
The primary function of insulin is to
Regulate blood glucose levels
How does insulin regulate blood glucose levels?
Insulin eases the active transport of glucose into muscle and fat cells
Insulin facilitates
Fat formation
Complete the sentence
Insulin inhibits the breakdown and movement of __________ _________
Stored fat
Insulin helps move amino acids into cells for?
Protein synthesis
Glucose unused by the cells stored in the liver and muscle cells are known as
Glycogen
Complete the sentence
If there is excess glucose it is converted into fat and stored as __________ ________
Adipose tissue
When does insulin release increase?
When blood glucose level rise
When does insulin levels decrease?
When blood glucose levels fall
Fill in the blank
When a person eats food, insulin levels rise in minutes, peak in ___ to 60minutes, and return to baseline in _____ to ______ hours
Peak 30-60 minutes, baseline 2-3 hours
What cells in the islets of Langerhans produce glucagon?
Alpha cells
Blood glucose levels increase during periods of
Hypoglycemia
Stress
Growth
Increased metabolic demands
Blood glucose control is essential to reduce complications that often affect the
Cardiovascular system, kidneys, eyes, and nerves
Fill in the blank
People with diabetes are at higher risk for ____ and ________ than people with out it.
Heart disease and stroke
Fill in the blank
____________ amputations occur ________ frequently in people with diabetes
Nontraumatic, more
What two terms refer to diabetes mellitus?
Diabetes, DM
Type 1 diabetes was formally known as
Type 1 diabetes mellitus, juvenile onset diabetes mellitus, or insulin dependent diabetes mellitus (IDDM)
Type 2 diabetes was formally known as?
Type 2 non insulin dependent diabetes mellitus (NIDDM) or adult onset diabetes
Explain the process of type 1 diabetes
An autoimmune response destroys the beta cells in the pancreas. Without insulin the cells starve and burn fats&proteins for energy causing ketosis.
What are the manifestations of type 1 diabetes?
Polyuria Polydipsia Polyphagia Weight loss Fatigue Malaise Blurred vision
List the Manifestations of type 2 diabetes
Polyuria Polydipsia Recurrent infections Obesity Fatigue Blurred vision Paresthesia
What viral infections have been linked to type 1 diabetes
Mumps, rubella, or coxsackie4
Type 2 DM is characterized by
Hyperglycemia due to insufficient insulin production and insulin resistance
Risk factors of type two diabetes
Obesity, physical inactivity, illnesses, increasing age and belonging to a high risk ethnic group
High blood glucose levels lead to
Cataracts, blurred vision, and destruction of peripheral nerves. Resulting in parethesias.
Treatment of diabetes is maintaining blood glucose levels through
Medications, diet, and exercise
Three laboratory tests used to screen for DM are
Plasma glucose level (PG), fasting blood glucose (FBG) and oral glucose tolerance test (OGTT)
What is the preferred diabetes laboratory test and why?
FBG (fasting blood glucose) because it is easier to administer, more convenient, and economical than the others
List the diagnostic criteria of diabetes
Plasma Glucose concentration greater than 200mg/dL
Eight hour fasting PG greater than 126 mg/dL
Two hour PG greater than 200
True or false
SMBG stands for self monitoring blood glucose
True
What insulin can be given IV?
Regular
True or false
Delayed insulin release from the pancreas, decreased tissue sensitivity to insulin, or both leads to decreasing glucose tolerance
True
Define pre diabetes
People at risk of diabetes
Most common diagnostic tests to monitor diabetes management are
FBG, glycosylated hemoglobin, urine glucose, ketone levels, serum cholesterol, and triglyceride levels.
Serum cholesterol and triglyceride levels are indicators of
Atherosclerosis and CVD
One must raise their HDL to what?
Greater than 45 mg/dL
LDL must be less than
100 mg/dL
List three rapid acting insulins.
Humalog (lispro)
Novolog (aspart)
Apidra (glulisine)
List two examples of short acting insulin
Regular
- Novolin R
- Humulin R
List intermediate insulin
NPH -Novolin N. Humulin R
Novolin NPH 70/30 regular