Diabète Flashcards

1
Q

Objectif de traitement

HbA1C

A

Plus petit que 7 %

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2
Q

Objectif de traitement

Glycémie à jeun

A

4,0 et 7,0 mmol / L

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3
Q

Objectif de traitement

Glycémie 2h postprandial

A

5,0 et 10,0 mmol / L

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4
Q

Thiazolidinediones

Mécanisme d’action

A

diminution résistance musculaire

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5
Q

Thiazolidinediones

E2

A

IC, oedème, cancer vessie, fractures

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6
Q

Thiazolidinediones

CI

A

IC

Dysfonction hépatique

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7
Q

Biguanines (metformine)

Mécanisme d’action

A

Inhibition néoglucogenèse

et secondaire diminution résistance musculaire

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8
Q

Biguanines (metformine)

E2

A

GI et acidose lactique

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9
Q

Biguanines (metformine)

CI

A

IC, IR, IH

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10
Q

Sécrétagogue de l’insuline

Mécanisme d’action

A

Augmentation sécrétion de l’insuline

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11
Q

Sécrétagogue de l’insuline

E2

A

hypoglucémie et gain de poids

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12
Q

Sécrétagogue de l’insuline

IC

A

IR sévère

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13
Q

Analogue de l’incrétine (GLP-1 et DPP-4)

Mécanisme d’action

A

Augmentation production insuline et diminution production glucagon

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14
Q

Analogue de l’incrétine (GLP-1 et DPP-4)

E2

A

Diarrhée / No

perte de poids

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15
Q

GLP - 1 désavantage

A

Production d’anticorps

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16
Q

Inhibiteur de alpha glucosidase

mécanisme d’action

A

Diminution absorption du glucose

17
Q

Inhibiteur de alpha glucosidase

E2

A

GI

perte de poids