Development, Repro, & Sexuality

Question 1

For a single-dose MTX regimen: after giving methotrexate (on day 1) to treat an ectopic pregnancy, bHCG levels should be checked on day _ and day _. bHCG levels should decrease by _% during these days, otherwise the patient needs another dose of methotrexate.

Answer 1

bHCG levels should decrease by 15% between days 4 and 7. (It is normal for levels to increase between days 1 and 4.) If no additional dose of MTX is needed, continue to trend bHCG weekly until 0. The two-dose regimen for MTX automatically gives a second MTX dose on day 4, otherwise the steps are the same.

Question 2

Options for terminating a pregnancy are either _ followed by _ 24 hours later or _. Options for ectopic pregnancy are _ or _. Options for miscarriage are _ followed by _ 24 hours later, _ alone, or _.

Answer 2

mifepristone followed by misoprostol vs D&C; methotrexate vs D&C; mifepristone followed by misoprostol vs misoprostol alone vs D&C

Question 3

Classic features of Turner syndrome are _.

Answer 3

short stature, webbing of the neck, shield chest, aortic coarctation (high UE BP and low LE BP), ovarian failure (streak ovaries)

Question 4

_ Syndrome causes hypogonadotropic hypogonadism due to deficiency of GnRH. It presents with delayed puberty, primary amenorrhea and _.

Answer 4

Kallman; anosmia

Question 5

Patients with _ will be phenotypically female but with a blind vaginal pouch, normal breast development, and scant pubic hair.

Answer 5

Complete Androgen Insensitivity

Question 6

Ambiguous genitalia can be seen in _ and _

Answer 6

Congenital Adrenal Hyperplasia, 5-Alpha Reductase Deficiency