Development of Visual Pathway Flashcards

1
Q

At what week does the visual system begin to develop?

A

3 weeks

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2
Q

What embryological tissue gives rise to the retina, the fibers of the optic nerve and smooth muscle of the iris?

A

Neuroectoderm

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3
Q

What embrylogical tissue forms the corneal and conj. epithelium, the lens and the lacrimal and tarsal glands?

A

Surface ectoderm

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4
Q

What embryological tissue forms the corneal stroma, sclera, choroid, iris, ciliary muscle, vitreous body and the cells lining the anterior chamber?

A

Mesenchyme

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5
Q

What part of the brain does the eye develop from?

A

Forebrain (specifically diencephalon)

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6
Q

Around what embryo day does the retina begin to develop?

A

30 days

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7
Q

Around what embryo day does the LGN begin to develop?

A

36 days

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8
Q

Around what embryo day does the cortex begin to develop?

A

40 days

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9
Q

People who become blind early tend to have a thicker visual cortex due to the failure of what?

A

Failure of pruning and retraction of processes

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10
Q

Initial steps of cell generation are under what 2 types of control?

A

Chemical or molecular control

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11
Q

Once synaptic connections are made between the cells, development is more influenced by what?

A

Electrical activity between the cells in the system

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12
Q

What retinal cells develop first?

A
  1. Ganglion
  2. Horizontal
  3. Amacrine cells
  4. Cone cells
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13
Q

What retinal cells develop second?

A
  1. Rods
  2. Bipolar cells
  3. Mueller glial cels
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14
Q

T/F: The central part of the retina is generated first and the peripheral parts later.

A

True

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15
Q

What guids the axons of ganglion cells to the optic nerve head?

A

Proteins

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16
Q

If an animal is kept in the dark, will the segregation of on-off responses of ganglion cells develop?

A

No

17
Q

If the electrical responses are blocked, will the segregation of on-off responses of ganglion cells develop?

A

No

18
Q

What guides the nasal retina nerve fiber axons into, through and out of the chiasm ?

A

Slits - extracellular matrix molecules

19
Q

What affects the guidance facts expressed by retinal ganglin cells in Albinos?

A

the lack of melanin in the pigment epithelium in the retina

20
Q

In albinos, some of the temporal half of the retina project abnormally tot he contralateral LGN. What does this cause in the patient?

A

Lack of binocular coordination between the 2 images/eyes