Development of the Nervous System Flashcards
Neural crest cells develop into:
cranial nerve sensory ganglion cells and dorsal root ganglion cells
postganglionic autonomic ganglion cells (sym and para)
chromaffin cells of adrenal medulla
melanocytes
schwann cells
what does the prosencephalon develop into?
Telencephalon= cerebral cortex, basal ganglion, amygdala, plus the lateral forament of monor
Diencephalon = thalamus, hypothalamus, posterior pituitary, pineal gland and the third ventricle
What does the mesencephalon develop into?
Midbrain + cerebral aqueduct
What does the rhombencephalon develop into?
Metencephalon = pons and cerebellum + 4th ventricle
Myelencephalon = medulla
What does the NS develop from?
Ectoderm, induced by the notochord
The notochord is made of..
Mesoderm
The sulcus limitans divides what two plates?
Alar plate (sensory pathways) Basal plate (motor pathways)
What is myeloschisis (spina bifida)
When the posteiror neuropore fails to close.
Three types:
spina bifida occulta
spina bifida cystica (meningocele and meningomyelocele)
rachischisis
Exencephalay:
failure of the cephalic neural tube to close, result sin failure of the skull to form, leaving the malformed brain exposed
incompatible to life
Hydrocephalus:
abnormal accumulation of CSF within the ventricular system, can lead the lateral ventricles pressing outward on the cortex and developing skull; since the cranial nerves have not fused, the skull expands.
Usually blockage/stenosis of aqueduct of Sylvius.