Development of the Foregut Flashcards
Where does the primitive gut tube extend from and to?
From the oropharyngeal membrane to the local membrane
What is the epithelial lining of the primitive gut tube derived from?
The endoderm
What is are the smooth muscle and connective tissue of the primitive gut tube derived from?
The surrounding visceral mesoderm
What are the visceral and parietal peritoneum of the primitive gut tube derived from?
The visceral and parietal mesoderm respectively
What suspended the primitive gut tube from the posterior abdominal wall?
The Dorsal Mesentry
Where does the dorsal mesentery extend?
From the Lower Oesophagus to the Cloaca
Where does the ventral mesentery extend?
From the Lower Oesophagus to the 1st part of the duodenum
What does the ventral mesentery form?
The lesser Omentum and the falciform ligament (umbilical vein)
What are the functions of the mesentries?
To carry blood vessels, lymphatics and nerves to and from the organs.
What undergoes remodelling to form the arteries of the GI Tract?
The vitelline arteries. They from the Coeliac Trunk, the Superior Mesenteric and the Inferior mesenteric arteries.
What are the Vitelline arteries?
A part of the vitelline circulation which carries blood to and from the yolk sac. They’re a branch off of the dorsal aorta.
During the formation of the Definitive Gut Lumen what happens in week 6?
Proliferation of the endoderm derived epithelial lining leading to the occlusion of the gut tube
During the formation of the Definitive Gut Lumen what happens between weeks 7 and 8?
Apoptosis of the epithelium occurs creating vacuoles. This is known as Recanalisation
During the formation of the Definitive Gut Lumen what happens by week 9?
The vacuoles come together to fully reconciles the gut tube
During the formation of the Definitive Gut Lumen, what happens to the epithelial lining?
It undergoes further differentiation
