Development Of Gut 1,2 Flashcards
What parts of GI make up the the;
- Foregut
- Midgut
- Hindgut
F: Oesophagus to Duodenum
M: Duodenum to Distal 2/3 of Transverse Colon
H: Distal 2/3 of Transverse Colon to Anus
What is the Vitelline duct?
What happens to it before birth
Connection between Midgut and Yolk Sac
Completely obliterates
List 2 abnormalities when the Vitelline Duct does not obliterate by birth
- Presence of a Meckel’s Diverticulum (Outpuch of Small Intestine)
- Connection between Midgut and Umbilicus (Fecal material comes out through Umbilicus)
What 2 types of folding occur in week 4?
What are the results of these?
Lateral:
- Creates ventral body wall (anterior body wall)
- Primitive gut becomes tubular (gut tube)
Craniocaudally:
- Creates cranial and caudal pockets/ head and tail ends (from yolk sac endoderm)
What is the Gut Tube that is made from Lateral Folding?
Where does it open? What is it covered by?
- An endoderm lined tube
- running the length of the body
- with blind pouches at head and tail ends
- Opens at Umbilicus
- Covered by Splanchnic (Visceral) Mesoderm
Compare the Splanchnopleuric and Somatopleuric mesoderm
What is the space between them called
- Splanchnopleuric: Combination of Splanchnic Mesoderm and Endoderm (of Gut tube)
- Somatopleuric: Combination of Somatic Mesoderm and Ectoderm
- Intraembryonic Coelom
What will the Intraembryonic Coelom eventually turn into?
How does it develop into this stage? (Very briefly)
- Begins as one large cavity
- Later divided by Diaphragm into Thoracic and Abdominal Cavities
Describe the Intraembryonic Coelom’s membrane
- 1 membrane lining whole cavity
- Specialises as cavities specialise into Pleura/ Pericardium/ Peritoneum and peritoneal cavity
What parts of the Peritoneum do the Somatic and Splanchnic Mesoderm develop into?
What is the space between called?
Splanchnic- Visceral
Somatic- Parietal
- Space between called the Peritnoneal Cavity (Is only a potential space, should be empty normally)
In the 4th week, what Membrane breaks, to effectively give us a “mouth”
Buccopharyngeal Membrane
In the 7th week, what membrane breaks, to effectively give us an “anus”
Cloacal membrane
What branches of the Abdominal Aorta supply each segment of the GI Tract?
Coeliac artery- Foregut
Superior Mesenteric- Midgut
Inferior Mesenteric- Hindgut
Name 1 non-GI derivative of the Foregut
Respiratory tract
What does the endoderm of the gut do in the 5th and 9th weeks?
5th: Proliferates rapidly, temporarily closing lumen
9th: Recanalises (Opens lumen again)
What happens in the Foregut in 4th week?
- A lung bud (respiratory diverticulum) forms ventrally
- A Tracheoesophageal Septum forms, separating Trachea and Oesophagus