Development 1 Flashcards
Multicellular life
cells, tissues, organs, systems, organisms
Stages of Development
- fertilization
- cleavage
- gastrulation
- organogenesis
Fertilization stage
Haploid egg + sperm fuse into a diploid zygote
1. Sperm contacts outer jelly coat
2. acrosomal reaction
3. bindins bond to receptors on egg
3b. sperm fuses with egg
4. cortical reaction
polyspermy
when more than 1 sperm nucleus enters the egg.
If happens it leads to wrong # of chromosomes.
Egg activation & Cleavage
Egg is activated & ready for cell division after fertilization.
Sperm & nucleus rapidly merges with the egg nucleus & the new zygote begins rapid cell division
Blastomeres
new cells created by rapid divisions
Blastula
resulting hollow ball of cells in cleavage
Yolk
When eggs are fertilized externally they have yolk. A viscous fluid containing nutrients for the embryo
blastocoel
hollow fluid filled space needed for gastrulation to occur
Gastrulation
Formation of the gut tube that has 3 layers in the embryo called the embryonic germ layer (ectoderm, endoderm, mesoderm).
Ectoderm
forms skin epithelium & nervous tissue. (Jaws, teeth epidermis of skin)
Endoderm
forms the lining of the digestive tract & related organs (liver, pancreas), thymus, throid
Mesoderm
a looser tissue that forms in the space between the endoderm & ectoderm (the coelom), skeletal & muscular systems
Protostomes (molluscs, annelids)
Spiral & determinate cleavage patter.
Mouth develops from blastopore.
Deuterostomes (echinoderms, chordates)
Radial & indeterminate cleavage patters.
Anus develops from blsatopore.
Organogenesis
The process in which organ rudiments develop from the three germ layers after gastrulation.
Cytoplasmic determinants
localized in the egg cytoplasm & end up in specific cells during cleavage
Induction
A process in which a group of cells or tissues influences the development of another group through close-range interactions.
Example: Neural tissue signals surface ectoderm to thicken with signaling molecules
notochord
axial mesoderm condensed into central strip of tissue (Chordates)
Neurulation
First steps in the formation of the brain & spinal cord in vertebrates
Somite
one of a series of blocks of mesoderm that exist in pairs just lateral to the notochord in a vertebrate embryo
Neural crest cells
In vertebrates - a region along the sides of the neural tube where it pinches off from the ectoderm.
Neural crest cells migrate to various parts of the embryo & form pigment cells in the skin & parts of the skull, teeth, adrenal; glands, peripheral nervous system.
Acrosomal reaction
discharge of hydrolytic enzymes from the acrosome, a vesicle in the tip of a sperm, when the sperm approaches or contacts an egg.
determinate cleavage
type of embryonic development in protostomes that rigidly casts the development fate of each embryonic cell very early