Detoxification Flashcards
1
Q
How can xenobiotics enter the body?
A
Can be absorbed across lungs, skin or ingested
2
Q
How are xenobiotics excreted?
A
In bike, urine, sweat and breath
3
Q
Which type of enzymes are mainly involved in Phase 1 reactions?
A
Microsomal enzymes
4
Q
Which type of enzymes are mainly involved in Phase II reactions?
A
Non-microsomal enzymes
5
Q
Where are microsomal enzymes found in the cell?
A
On the smooth endoplasmic reticulum
6
Q
Where are non-microsomal enzymes found in the cell?
A
Cytoplasm and mitochondria
7
Q
What are xenobiotics?
A
Foreign chemical substances not usually found in the body eg drugs
