Dermatology - skin conditions

Question 1

Name some skin conditions

Answer 1

Psoriasis, eczema, contact dermatitis

Question 2

Aetiology of psoriasis?

Answer 2

HLA associated and T cell mediated = early proliferation of kerationcytes

Question 3

How would psoriasis present?

Answer 3

Well defined - red w/ scaly surface

Trunk and limbs mainly - can be nails and scalp

Question 4

What complications can you get with psoriasis?

Answer 4

Psoriatic arthritis

Question 5

Tx of psoriasis?

Answer 5

Reduce keratinocyte proliferation: retinoid, dithranol

Immune suppression: steroid, biologics, TNF blockers

Question 6

Aetiology of eczema?

Answer 6

IgE mediation (no HLA) with late keratinocyte proliferation

Question 7

How would eczema present?

Answer 7

Poorly defined - red w/o scales
Often children allergy (atopic)
Face and hands - not nail and scalp

Question 8

Tx of eczema?

Answer 8

Identify trigger
Emollient cream/ topical steroid
Antihistamine for itch
Ab in infected

Question 9

2 examples of oral manifestation of skin disease?

Answer 9

1. Lichen plants - itchy red rash on flexor surface –> band like T cell infiltrate and saw shaped rete ridge
2. Herpes infection