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Dermatology > Dermatology Pharmacology and Prescribing > Flashcards

Dermatology Pharmacology and Prescribing Flashcards

1
Q

What is pharmacokinetics?

A

The effect of body on the drug

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2
Q

What is pharmacodynamics?

A

The effect of the drug on the body

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3
Q

What is distribution?

A

Where the drug goes

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4
Q

What is metabolism?

A

How is the drug processed

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5
Q

What factors can affect pharmacodynamics?

A

Age
Pregnancy
Drug interactions
Pharmacogenetics

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6
Q

What is topical therapy?

A

Medication that is applied to the skin

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7
Q

What is the vehicle of a drug?

A

pharmacologically inert, physically and chemically stable substance that carries the active drug

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8
Q

What vehicles can be used?

A
  • Solution
  • Cream
  • Lotion
  • Gel
  • Foam
  • Tape
  • Paste
  • Spray powder
  • Shampoo
  • Ointment
  • Paint
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9
Q

What is the most important factor in topical steroids?

A

Potencies

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10
Q

Are topical steroids safe?

A

Yes

If used appropriately

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11
Q

How many g is a fingertip unit?

A

0.5g

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12
Q

What are the uncommon side effects of topical steroids?

A 
Thinning/atrophy 
Striae 
Bruising 
Hirsutism
Glaucoma 
Systemic absorption 
Cataracts
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13
Q

What are the 3 classes of drugs in dermatology?

A

Retinoids
Traditional immunosuppressants
Biologics

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14
Q

Why should child baring age women be careful with retinoids?

A

Because they are teratogenic

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15
Q

What factors are associated with poor medication adherence from patients?

A 
Psychiatric co-morbidities
Slower acting agents
Multiple applications per day
Lack of patient education
Cosmetic acceptability of treatments
Unintentional non-adherence
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16
Q

What type of analogues are retinoids?

A

Vitamin A analogues

17
Q

What conditions are retinoids used in?

A

Acne
Psoriasis
Cutaneous T cell lymphoma
Hand eczema

18
Q

What are some side effects of retinoids?

A

Dry lips

Dry skin

19
Q

What do immunosuppressants treat?

A

Inflammatory skin conditions

20
Q

What is there increased risk of with immunosuppressants?

A

Malignancy

Serious infection risk

21
Q

What needs constantly monitored when on immunosuppressants?

A

Bloods

22
Q

What do biologic do?

A

Designed to inhibit specific components of the immune system

23
Q

What is the main drawback to biologics?

A

Money

Expense

24
Q

What is there a risk of with biologics?

A

Infection

Malignancy

25
Q

What have biologics been a revolution for the treatment of?

A

Advance melanoma

Dermatology (3 decks)

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