Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Derm Placement Y5 > Dermatology of Systemic Disease > Flashcards

Dermatology of Systemic Disease Flashcards

1
Q

What is SOAP BRAIN MD?

A

Lupus symptoms:

Serositis – Pleurisy, pericarditis
Oral ulcers
Arthritis
Photosensitivity
Blood disorders
Renal involvement
Antinuclear antibodies
Immunologic phenomena
Neurologic disorder
Malar rash
Discoid rash

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the dermatological presentation of acute cutaneous lupus?

A

Malar rash
Bullous rash
Photosensitivity
Maculopapular rash
Mucosal involvement
Diffuse hair loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the management of acute cutaneous lupus?

A

Blood tests
Urine dipmab
skin biopsy
MDT

Tx = systemic steroids, hydroxychloroquine or rituximab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is subacute SLE?

A

Multiple well demarcated annular patches with scales, erythema and are polycyclic on the upper arm and back

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is discoid lupus?

A

Crusty/ Scaly erythmatous discoid lesions with erosions

Treat with steroids/ hydroxychloroquine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Is lupus photosensitive?

A

Yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is this?

A

Scleroderma (CREST)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the parts of CREST?

A

Calcinosis, Raynaud’s phenomenon, Oesophageal dysmotility, Sclerodactyly, and Telangiectasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What Ix do you do for CREST?

A

ENA: Anti centromere, Anti Scl 70

OGD and pH manometry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the treatment of CREST?

A

Reynaulds: stop smoking, stay warm, diltiazem

Calcinosis: curettage and cautery

Methotrexate

Iloprost

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is this?

A

Morphoea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What kind of rash does morphoea present with?

A

Red bordered well demarcated hairless rash with thickened skin and an ivory centre.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the types of morphoea?

A

Pansclerotic

Linear (like you’ve been hit with a sword and muscle atrophy)

Atrophic/ guttate

subcutaneous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the treatment of morphoea?

A

Steroids, retinoids, Vit D analogues

Phototherapy

Methotrexate, hydroxychloroquine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What does dermatomyositis present with?

A

A heliotropic rash on the eyelids (erythmatous and oedematous)

Gottrons papules (erythmatous scaly rash on the knuckles)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the other features of dermatomyositis?

A

Poikoloderma

Ragged cuticles

Mega capillaries

Photosensitivity

Muscle weakness

Reynaulds

calcinosis

17
Q

Which antibody is linked to antisynthetase syndrome ( a type of dermatomyositis)?

A

Anti Jo 1

Mechanics hands, fever, myositis, reynaulds, arthritis, ILD

18
Q

What investigations do you do for dermatomyositis?

A

ANA

ENA

Anti Mi2 and Anti Jo 1

CK

adolase

AST/ALT/ LDH

Skin biopsy

EMG

MRI

Muscle biopsy

19
Q

What is the treatment of myositis?

A

MDT care

Sun protection

oral prednisolone/ methotrexate/ azathioprine

IVIG

mycophenolate

20
Q

What are oedema blisters?

A

Occur in acute exacerbation of odema creating conditions

Sterile fluid

Resolves spontaneoulsy when cause is treated

21
Q

What are the bullae like in bullous pemphigoid?

A

Pruritic

Prodromic oedema and erythematous rash

Requires skin biopsy and antibody test on bloods

22
Q

What does pemphigus vulgaris look like?

A

Erosions - bullae pop as they are thin walled and superficial

Appear in oro-nasal area and genitals

23
Q

Which antibodies do you test in pemphigus vulgaris?

A

Anti desmoglein 1 and 3

skin biopsy

24
Q

Which rash is linked to coeliac diseases?

A

Dermatitis herpetiformis

25
Q

What type of rash is dermatitis herpetiformis?

A

polymorphic rash with macules, papules, patches and vesicles that are erythmatous occuring over the extensors and buttocks

V. itchy

26
Q

What are the Ix for dermatitis herpetiformis?

A

Skin bx

Coeliac screen

OGDS (duodenal biopsy)

27
Q

What is the management of dermatitis herpetiformis?

A

Gluten free diet

Oral prednisolone

Dapsone

28
Q

Which rashes may occur in sarcoidosis?

A

Erythmatous scaly nodules on nose = lupus pernio

Large plaques over body

Darier Roussey Disease

Scar sarcoidosis

Erythema nodosoum

Calcinosis cutis if high calcium

Pruritis

29
Q

What are the investigations of sarcoidosis?

A

Vitaamin D

ACE

Quantiferon Tb assay

typical bloods

CXR

Skin biopsy

spirometry

30
Q

What is the management of sarcoidosis?

A

Oral pred/ methotrexate/ azathioprine

Tetracycline

Hydroxychloroquine

Can resolve spontaneously

31
Q

What can vasculitis rashes look like?

A

Small Vessel: Purpuric, Macules Urticarial with purpura, Haemorrhagic vesicles, Haemosiderin deposition

Medium Vessel: Livedo reticularis, retiform purpura, ulcers, gangrene

32
Q

What are the causes of small vessel vasculitis?

A

Idiopathic

Infection

Drugs

Inflammatory

Malignancy

33
Q

How does HSP present?

A

Child with post strep who mayve had medications

Purpuric rash and abdo pain + haematuria

In adults: purpuric rash, haematuria and arthralgia

34
Q

What are the investigations for HSP?

A

Anti-streptolysin O Titre

IgA

Skin biopsy- IgA

Renal (ESKD)

35
Q

What is the vasculitis screen?

A

Coagulation and FBC

ANA/ENA

RF, antidsDNA, ANCA, C3, C4

Anti Strep O, HBV/HCV and cryglobulins

Ig/ serum electrophoresis

urine dip

CXR

36
Q

What is the treatment of vasculitis?

A

Presnisolone

Dapsone

Colchicine

Methotrexate

Moniter U+Es and urinalysis on drugs

Derm Placement Y5 (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions