Dermatology Flashcards

1
Q

Name some causes of erythema nodosum

A
  • Inflammatory bowel disease
  • Streptococcal infection
  • Drugs - OCP, sulfonamides
  • Malignancy
  • Acute sarcoidosis
  • TB
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is rosacea? Name some aggravating factors

A

Relapsing-remitting chronic inflammatory facial dermatosis characterised by erythema and pustules.

  • Sun exposure
  • Emotional stress
  • Hot/cold weather
  • Alcohol
  • Spicy foods
  • Exercise
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How is rosacea managed?

A
  • Avoid triggers
  • Antibiotics - prolonged courses of topical or systemic
  • Refer to dermatology if:
    • Rhinophyma
    • Ocular complications
    • Failure to respond to treatment
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is lyme disease? Name some clinical features

A

Infectious skin disease caused by the bacteria Borrelia burgdorferi which is spread by ticks (usually from deer or sheep)

  • Erythema migrans (red macule/papule) on upper arm/leg/trunk 7-10d after a tick bite
    • Expands to form a ring with central clearing
  • Flu like symptoms
  • Lymphadenopathy
  • Splenomegaly
  • Arthralgia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How is lyme disease managed?

A
  • Confirm diagnosis with serology (antibodies)
  • Doxycycline 2-3 weeks
  • Removal of ticks using fine tweezers
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is vitiligo?

A

Autoimmune destruction of melanocytes which cause smooth, sharply defined white macules or patches

  • Often symmetrical
  • May also affect hair
  • Associated with pernicious anaemia, Addisons and thyroid disease
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How is vitiligo managed?

A
  • Sunscreen use for affected areas
  • Camouflage cosmetics
  • Refer to dermatology:
    • Topical steroids
    • Topical calcineurin inhibitors (tacrolimus)
    • Phototherapy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Name some causes of hair loss

A
  • Male pattern baldness
  • Hypothyroid/pituitary
  • Iron deficiency
  • Malnutrition
  • Alopecia
  • Ringworm
  • Trauma
  • SLE
  • Burns
  • Radiation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How is alopecia managed?

A
  • Topical/local injection/systemic steroids
    • +/- contact immunotherapy
  • Pscyhological support
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How is eczema diagnosed?

A

Itchy skin + >/3 of:

  • Itching in skin creases
  • History of asthma or hay fever
  • Onset in first 2 years of life
  • Generally dry skin
  • Visible flexural eczema

Also: lichenification and dry skin, psychological issues, sleep problems

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How is eczema treated?

A
  • Advice:
    • Loose cotton clothing (avoid wool)
    • Avoid excessive heat and other irritants
    • Keep nails short
    • Gloves in bed
  • Emollients 3-4/day
  • Antipruritic (lauromacrogol)
  • Topical/oral steroids
  • Antibiotics if infected
  • Topical immunosuppressants (tacrolimus)
  • Antihistamines
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How does contact dermatitis present?

A

Most commonly affects hands

  • Acute
    • Itchy erythema
    • Skin oedema
    • Papules/vesciles/blisters
  • Chronic
    • Lichenification
    • Scaling
    • Fissuring
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How is contact dermatitis managed?

A
  • Identification of allergen/irritant - occupation, hobbies, sports, chemical use, detergent etc
    • Patch testing
  • Exclude irritant from environment
  • General advice on hand care
    • Avoid detergents, cleaning fluids, shampoos
    • Wear plastic gloves when chopping veg/fruit
  • Emollients
  • Topical steroids
  • Exclude/treat secondary infection
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is seborrhoeic dermatitis?

A

Chronic scaly eruptions affecting the scalp, face and/or chest

  • Excessive dandruff
  • Itchy, scaly erythematous eruption affecting sides of nose, eyes, ears, hairline
  • Most common in young men
  • Can be indicator for HIV infection
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How is seborrhoeic dermatitis managed?

A
  • Imidazole (antifungal) and hydrocortisone
  • Ketoconazole/coal tar shampoo if scalp lesion
  • Offer HIV testing if severe
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is urticaria? How is urticaria managed?

A

Superficial, itchy, red swellings/weals on the skin

  • Antihistamines for itching (cetirizine)
  • Topical menthol cream
  • If severe - short course steroids (prednisolone)
17
Q

What is acne? Name some causes

A

Chronic inflammatory condition characterised by comedones, papules, pustules, cysts and scars.

  • Androgen secretion increases sebum excretion
    • Pilosebaceous duct blockage
    • Colonisation with propionibacterium acnes
  • Endocrine - PCOS, Cushings
  • Cosmetics
  • Drugs - steroids, androgens
18
Q

How is acne treated?

A
  • General advice
    • Try not to pick
    • Wash with soap and warm water BD
    • Use water-based emollient
  • Medication
    • Benzoyl peroxide
    • Topical retinoids
    • Topical antibiotics (clindamycin)
    • Oral antibiotics
    • Anti-androgen (for girls)
19
Q

What is psoriasis?

A

A chronic, non-infectious inflammatory skin condition characterised by epidermal cell proliferation (x20) and decreased turnover time (4 days)

  • Associated with inflammatory bowel disease
    • Crohns > UC
20
Q

Name some causes of psoriasis

A
  • Genetic
  • Environmental triggers
    • Trauma
    • Infection
    • Drugs - Beta blockers, NSAIDs, lithium
    • Alcohol
    • Sunlight
    • Stress
21
Q

How is psoriasis managed?

A
  • Psychological reassurance / self help groups
  • Emollients
  • Drugs
    • Salicylic acid (paste)
    • Coal tar - anti-inflammatory
    • Vitamin D analogue
    • Dithranol
    • Topical retinoids
    • Topical steroids
22
Q

What is this?

A

Basal cell papilloma

  • Common in >60y
  • Multiple
  • Common on trunk
  • Warty, pigmented nodule
  • Can be picked off
  • Removal not always required
23
Q

What is this?

A

Malignant melanoma (ABCDEF)

  • Asymmetrical outline
  • Border irregularity
  • Colour variation
  • Diameter (>/=7mm)
  • Evolution - changes in size, shape, colour, elevation
  • ‘Funny-looking’ mole
24
Q

How is malignant melanoma treated?

A
  • Refer suspcious lesions to dermatology
  • Complete excision
  • Regional node dissection if involved
  • Adjuvants (minimise relapse)
    • Interferon alpha-2b
    • Bevacizumab (VEGF inhibitor)

NOT chemo or radio sensitive

25
Q

What is this?

A

Squamous cell carcinoma

  • Most common in men aged >55
  • Develops in sun-exposed sites (face, neck, hands) or areas of chronic inflammation
  • Rapidly growing red papule/non-healing skin lesion
    • +/- background of actinic keratosis
  • Ulcerated nodule
  • Bleeding
  • 5-10% metastasise
26
Q

What is this? What types are there?

A

Basal cell carcinoma (superficial)

  • Most common form of skin cancer
  • More common in older patients
  • Hair-bearing skin
  • Light-exposed areas
  • 3 types:
    • Nodular - small, pearly nodule (associated with telangiectasia)
    • Superficial - scaly, erythematous plaque
    • Morphoeic - waxy indurated plaque
27
Q

What is impetigo?

A

Superficial skin infection due to staph aureus

  • Common in childhood
  • Thin walled blister - yellow crusted lesion
  • Most common on face
  • Treat with topical antibiotics
28
Q

What is this? How is it treated?

A

Cellulitis - painful, tender reddened area with well-defined edges

  • Mark the area
  • Flucloxacillin or clarithromycin
  • If severe/systemically unwell - admit for IV antibiotics
29
Q

What is this? Name some risk factors and treatment

A

Necrotising fasciitis = soft tissue infection

Risk factors = trauma/surgery, IV drug user, alcoholic, diabetes, immunosuppression

Treatment = IV antibiotics, surgical debridement

30
Q

How is melanoma investigated?

A
  • Clinical - skin, lymph nodes, abdo, neuro
  • Dermoscopy
  • Biopsy (usually excision) - histological analysis and staging
  • CXR - mets
  • Serum biochemistry (+LDH)
31
Q

Name some causes of melanoma

A
  • Sunlight (UV radiation)
    • Sunburn
    • Sunbeds
  • Genetics
  • Benign pigmented naevi
  • Immunosuppression (organ transplant)
32
Q

What indicated poor prognosis in melanoma?

A
  • Deep Clarke’s level
  • Large Breslow thickness
  • Ulceration
  • Mucosal or nodular
  • Male
  • Age > 50
33
Q

How is squamous cell carcinoma managed?

A
  • Surgical excision- histological assessment of margins
  • Regional lymph node dissection if involved
  • Moh’s micrographic surgery if at difficult site
  • Cryotherapy or electrosurgery (small/low-risk)
  • Radiotherapy (small/well-localised)
  • Chemotherapy is disseminated disease
  • Cetuximab
34
Q

How is basal cell carcinoma managed?

A
  • Surgical excision - assess histology and resection margin
  • Moh’s micrographic surgery if >2cm or difficult margins
  • Cryotherapy/electrosurgery/radiotherapy
35
Q

Name the risk factors for BCC and SCC

A
  • UV radiation
  • Previous skin cancer
  • HPV
  • Ionising radiation
  • Chronic inflammation
  • Immunosuppression