Dermatology Flashcards
dr derm word for itching
pruritic
what meds can cause derm reactions
sulfonamides
penicillins
cephalosporins
what are 2 examples of “common” systemic illnesses that can cause derm issues
hyperadrenocorticism
hypothyroid
what is dermogram
lesion distribution chart
what is primary derm lesion
Initial eruption that develops spontaneously directly related to underlying disease
appear & disappear quickly
what is secondary derm lesion
evolve from 1° lesion or induced by pt response or external factors
stay around for longer than 1° lesion
Macule
or
patch
Macule: change in skin color w/o inflammation < 1 cm
patch: change in skin color w/o imflammation > 1 cm

purpura, petechial, ecchymoses
type of macule or patch caused by bleeding into skin
name NB size (eg. petechia = pinpoint, ecchymoses = bigger than pinpoint)

Papule
small, solid elevation in skin up to 1 cm, (inflammation present)

plaque
coalescence of papules forming flat topped elevation >1 cm
e.g. a hot spot great example!

pustule
small elevation of epidermis filled w/ pus

vesicle
elevation of pidermis filled w/ clear fluid

bulla
vesicle >1 cm

wheal
sharply delineated lesion of edema
in humans = hives
in animals = urticaria
ACUTE CS

nodule
solid raised palpable lesion >1 cm
can include abscess (fluctuant lesion in dermis or SQ from pus)

Nodule: Tumor
Large palpable mass - neoplastic

cyst
epithelial lined cavity with solid or fluid material
- sebaceous most common
- arise from dermis layer structures not epidermis*

alopecia
absence of hair from area where it is normally present
- Important to ask if pruritis present for ddx of endocrine dz or not (ectoparasite or something else)

Scale
accumulation of loosse fragments of horny layer of skin
seborrhea sicca
seborrhea oleosa

crust
accumulation of dried serum, exudate on surface of skin (scab)

follicular casts
accumulation of keratin & sebaceous material stuck to a hair shaft

comedone
dilated hair follicle filled w/ debris

another derm lesion that can be caused by hypothyroid or hyperadrenocorticism
epidermal collarette
scale arranged in circular pattern
associated w/ pustule, vesicle or bullae

scar
fibrous tissue has replaced the damaged dermis or s/c tissue

excoriation
linear abrasion of skin
- self trauma

erosion
shallow ulcer that does not break basal epidermal layer

ulcer
break in epidermis w/ exposure of dermis

fissure
linear cleavage (cracks) in epidermis or dermis caused by dz or injury

lichenification
thickening & hardening of skin
exaggerated skin lines
sign of chronic issue, time enough for melanocytes to migrate to area causing pigmentation

callus
localized hyperplasia of the stratum corneum of the epidermis caused by pressure or friction

Elbows & lateral hock areas are common sites for callus formation in the dog
name this skin parasite

demodex
what can be seen on this skin cytology

neutrophils & streptococci
what can be seen on this skin cytology

neutrophils & rods
what can be seen on this cytology

yeast & cocci
what is here

malassezia yeast
flourescence detected or not?

detected!
now if confirmation needed can pluck some hairs with known fluorescence and place in DTM
When is a fungal culture indicated?
All cats w/ skin dz
Dogs w/ inflammatory skin lesions
Your dog has suddenly developed these primary lesions - what are they?

wheals
What is this primary lesion?

vesicle
What is this organism?

Malassezia pachydermatitis
Which test is best to identify know environmental allergens causing atopy, after performing your initial dermatological exam?
intradermal allergy test
What is the most common cause of pruritus in a 4 month old dog?
Flea bite dermatitis
What is the most likely cause for this skin condition?

Flea allergic dermatitis
Atopic dermatitis is cause by what type of reaction?
Type 1 hypersensitivity reaction
Flea allergic dermatitis is caused by what type of reaction?
Type 1 hypersensitivity
Which is the second most common cause for an allergic dermatitis in a 4 mo puppy?
Food allergens!
in dogs <6 mos of age what is the order of the top three commom causes for an allergic dermatitis?
- Fleas
- Food allergens
- Environmental allergens
in dogs >6 mos of age what is the order of the top three commom causes for an allergic dermatitis?
- Fleas
- Environmental allergens
- Food allergens
Which of the followind treatments doesn’t show fair to strong evidence to control pruritis in an atopic dog?
- Glucocorticoids (Prednisolone)
- Cyclosproine A (Atopica)
- Antihistamines (Chlorpheniramine)
- Skin lipid therapy (Duoxo)
- Antihistamines (Chlorpheiramine)
show weak evidence of effectiveness!
Carbohydrates is the most common type of food allergen in dogs & cats
True or False
False!
- # 1 = proteins*
- # 2 = glycoproteins*
Hydrolysed food diets can be used for food allergy dogs. Which statement is false?
- Protein particle sizes are <3000 to 10,000 Daltons in most foods
- Hydrolysed food is more unpalatable compared to regular diets
- Owner compliance is easily obtained
- The lipid & carbohydrate source is also hypoallergenic
- The lipid & carbohydrate source is also hypoallergenic
Which one of the following products would give you good local & environmental control in a dog dxd w/ FAD
- Frontline (fipronil)
- Advantage (imidocloprid)
- Permethrin dip
- Capstar (nitenpyram)
- Advantage (imidocloprid)
An owner has decided on intradermal allergy testing & hyposensitisation. According to literature - what % of dogs will get a good to excellent control of atopic dermatitis through hyposensitisation?
- 100%
- 75%
- 50%
- 25%
- 50%
Which ONE of the following is not a way to diagnose contact dermatitis?
- Skin bx & histopathology
- Patch test
- Corticosteroid response
- Mechanical barrier (jacket/jersey)
- corticosteroid response
what type of pyoderma is this

surface pyoderma = hot spot
what type of pyoderma is this

superficial pyoderma = pustules
what type of pyoderma is this

superficial pyoderma = papules or pustuls
what type of pyoderma is this

deep pyoderma
what type of pyoderma is this

deep pyoderma
what are the characteeristics of surface pyoderma
mixed bacterial population
cytology critical
never culture
Tx: topical
what are the characteristics of superfcial pyoderma
overwhelmingly Staphylococcus
cytology suportive
s__ometimes culture
Tx: systemic & topical
what are the characteristics of deep pyoderma
Mostly Staph. but can be mixed
Cytology often negative
Frequently cultured
Tx: systemic, long term, topical
when is culture mandatory
intracellular rods on cytology
hx of MSRP, MSRA
what are benefits of topical tx
helpful
decr. duration of systemic Abs
prophylactical use
little to no side effects
indication for benzoyl peroxide product
pyoderma w/ oily seborrha or comedones
indication ofr chlorhexidine product
pyoderma w/ dry seborrhea or normal skin/coat
what are the 2 special topicals
Mupirocin
silver sulfadiazine
mupirocin info
bacteriostatic @ low conc. / bactericidal @ high conc.
effective vs G + including MRSA
silver sulfadiazine
topical sulfonamide/silver antibacterial
used on burns
activity vs Pseudomonas
can be prepared w/ water for ear administraion
what are 1st tier systemic Abs for empiric tx
1st gen cephalosporins = cephalexin
amoxi/clav
clindamycin
what are 2nd tier empirical Abs
sulfas
erythromycin
lincomycin
doxycyline
what are 2nd tier based on C/s results ideally
chloramphenicol
rifampin
amikacin
what are 3rd tier LAST RESORT based on c/s results Abs
fluoroquinolones
3rd gen cephalosporins
USE ONLY IF: no other antibiotic is a feasible option
culture shows suceptibility
how long to tx pyoderma
superficial:
3-4 wk min
1 wk beyone resolution
deep
3-12 wks
2 wks beyond resolution
signs often appear improved but don’t stop tx prematurely
what is another name for acute traumatic pyodermatitis
hot spot
what is a common superficial pyoderma puppies get
puppy pyoderma or impetigo
what type of pyoderma is nasal folliculitis/furunculosis
superficial & deep pyoderma
what type of pyoderma is chin acne or chin pyoderma
deep pyoderma
what type of pyoderma is a lick granuloma
deep pyoderma
very common
AKA: acral lick dermatitis
what are the CS of mucocutaneous pyoderma
mucocutaneous swelling, erythema, crusting
affects lps symmetrically, commisures affected
what is the pathogenesis of pyotraumatic dermatitis
2o to underlying dermatitis (flea allergy)
CS of hotspots
lesion, red, moist, exudative, crusting
denuded
painful
lesions in areas of primary irritation
Dx & tx of hotspots
typical lesions w/ associated cause
response to tx
antibacterial disinfectant
antibioti/steriod
seek predisposing cause
pathogenesis of impetigo & CS
bacterial dz caused by Staphylococcus spp.
young dogs
poor husbandry
Vesicales/ pustules
non-follicular pustules
ventral hairless areas
Dx of impetigo
typical CS
cytology
tx: antibacterial shampoos
toical antibiiotic washes/creams
pathogenisis of superficial pyoderma
Staphylococcus pseudintermedius
superficial hair follicle
self trauma
parasistic infestation
folliculitis may progress to furunculosis to cellulitis
3 most common causes of folliculitis in dogs
bacterial
dermatophytes
Demodex
CS of superficial pyoderma
tiny pustules with hair shaft protruding from center
follicular papule
patchy focal alopecia (moth eaten)
epidermal collarettes
scaling - seborrhea
hyperpigmentation or excoriations
Dx of superficial pyoderma
recognition of lesions
cytology
- degen. meutrophils, phagocytosed cocci, proteinaeous backround
tx of superficial pyoderma
Abs 21-28 days min
1 WK PAST RESOLUTION
antibacterial shampoo
what is important to recognize about deep pyodermas
there could be underlying disorder
pathogenesis of deep pyoderma
bact adhesion is prerequisite
bacteria can produce toxins
compromised skin defense > infection 2o usually, try to find underlying dz
Staphylococcus pseudintermedius
allergy most common predisposing cause
follicular pathology
Ehrlichia, Distemper (dogs), retrovirus (cats)
CS of deep pyoderma
breeds: GSDs, Bull terriers
deep draining tracts, clusters of ulcers, necrohemorrhagic purulent bullae or abscesses
What is a ddx for deep pyoderma in light haired dogs
SCC
what about pyoderma in cats
feline pyoderma is very rare!
Dx of deep pyoderma
cytology
- pyogranulomatous exudate
- cocci found
histopathology
- biopsy - infection may mask underlying dz
- allergy = flea, food, atopy
bact culture and antibiogram
what are the rules when tx deep pyodermas
use B-lactamase resistant penicillins
if multiple organisms cultured - TX S. pseudintermedius first!
dosage must be high enough
tx long
common Abs for deep pyodermas
Amoxi/clav
cephalexin
clindamycin
pathogenesis of Actinomyocosis
Actinomyces organisms
trauma, penetrating wounds
CS:
SQ abscesses, draining tracts
Exudates, thick, yellow-grey, hemorrhagic, foul smelling +/- sulphur granules
Dx Actinomyces
Anaerobic culture
DDx nocardiosis
Tx: surgical debulking
clindamycin
Px for cure is guarded!
pahtogenesis of nocardiosis
G + filmentous aerobe
CS same as Actinomyces
pyothorax
Dx of nocardiosis
FNA/cytology
Histopathology
Culture
Tx: surgical debulking, drainage
Px: guarded
pathogenesis of opportunistic myobacteriosis
saprophytic mycobacterium
CS: slow developing, sq nodules, etc.
Dx of Mycobacterium
cytology
histopathology
culture
Tx: wide surgcal excision
pathogenesis of skin fold pyoderma aka intertrigo
skin folds
maceration
superficial infection
CS: lip folds in spaniels, facial folds in bulldogs, tail root folds, vulva folds, body folds in Shar Pei
Dx & Tx of intertrigo
Dx: clinical presentation, signalment
Tx: shampoos, rinses, topcal Abs
etiology of Malassezia dermatitis
dogs - Malassezia pachydermatis
cats - M. sympodialis & globosa
ear (otitis externa), lip folds, ventral neck, axilla, interdigital, perianal. May generalize! CHECK FOLDS! CHECK EARS!
commensal - 2o infections
hypersensitivity to yeart product & antigens
signalment seen w/ Malassezia dermatitis
WHWT
what is malassezia associated with
allergic dermatitis
endocrinopathies
keratinization disorders
immunosuppression
CS malassezia
pruritus
malodor
erythema, greasy scaly plaques
paronychia (nail inflammation)
CS for dogs & malassezia
concurrent underlying dz
rancid like odor
ears: black wax & rancid
hair: red-brown color
CS for cats & malassezia
Rare
immunosuppressive dz (FIV, FeLV)
dx malassezia
cytology
>2/HPF (1000x) important
tx of malassezia
id & tx underlying factors if possible
topical: anti yeast shampoos 2-3 x wk
systemic: ketoconazole, itraconazole (better < hepatic side effects)
pathogenesis of dermatophytosis
- Microsporum canis (NB), M. gypseum, Trichphyton metagraphytes*
- 70% are M. canis*
fungal spores can last long in environment
young, immunosuppressed
- FeLV, FIV
- E. canis
- endocrinopathies
- malignancies
- steroid use
*
what is important to remember about dermatophytosis
ZOONOTIC
M. canis also the most common fungal infection in humans
Dx dermatophytosis
Wood’s lamp
mocroscopy of hair pluck
fungal culture
biopsy
DDx in dogs: bact folliculitis, demodecosis
facial lesions (dogs) - pemphigus foliceous/erythematosus
mgmt of dermatiophytosis
tx underlying dz, tx source, tx organizm
topical therapy: clip around lesions/wb
topical shampoos
systemic tx: griseofulvin, ketoconazole, itraconazole
6-12 mos
cattery/multi-cat households dermatophytosis management
separate infected animals
tx individuals
toothbrush cultures of all cats
decontaminate environment