Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MTB STEP 3 > Dermatology > Flashcards

Dermatology Flashcards

1
Q

Name the bulls and blistering skin diseases- most have pemphigus or “p” in the name.

A

1) Pemphigus Vulgaris
2) Bullous Pemphigoid
3) Pemphigus Foliaceus
4) Porphyria Cutenous Tarda
5) Drug/Hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Causes of pemphigus vulgaris?

A

Idiophatic
Ace inhibitors
Penicillamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Characteristic of P vulgarism?

A

Thin fragile skin that comes off easily - Nikolskly sign
Age: 30-40s
Severity: Life-threatening
Mouth involvement: yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Diagnosis of P Vulgaris?

A

Skin biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Tx of P vulgarism?

A

Steroids -> Prednisone –if doesn’t work– use Azathioprine, Mycophenolate, Cyclophosphamide.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Causes of Bullous pemphigoid?

A

Most often drug related -sulfa being a biggie.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Characteristics of B. pemphigoid?

A

Deep, thicker walled blisters. Less likely to rupture.
Age: 70-80s
Severity: Mortality is less likely – less chance of infection
Mouth involved: rarely

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Dx of B. pemphigoid?

A

Biopsy– Immunofluorescent antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Tx of B. pemphigoid?

A

Steroids- Prednisone

Alternative: Tetracycline or Erythromycin with nicotinamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Causes of Pemphigous Foliaceus?

A

Autoimmune or drug induced–ACEi or NSAIDs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Dx and Tx

A

Biopsy

Steroids or Azathioprine, Mycophenolate or Cyclophosphamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Causes of porphyria cutanea tarda

A

Bad porphyrin metabolism = photosensitivity reaction because high accumulation of porphyrin in the skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Associated with PCT?

A 
Alcoholism 
Liver dz
Chronic hepatitis C- other liver Dzs
Oral Contraception
Diabetes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Characteristics of PCT

A

Sun exposure form non-healing blisters
Skin can become hyper pigmented
Hypertrichosis of the face– abnormal amount of hair.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Dx of PCT

A

Urine test – look for uroporphyrins 2-5 higher than coproporphyrins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Tx of PCT

A 
Stop drinking EtoH
Stop all estrogen use
Sun screen 
Phlebotomy to remove iron. Deferoxamine.
Chloroquine to increase the extraction of porphyrins.
17
Q

Different types of Drug Eruption/Hypersensitivity skin lesions?

A 
Urticaria
Moniliform Rash
Erythema Multiforme
Stevens-JOhnson Syndrome
Toxic Epidermal Necrolysis
Fixed drug reaction
Erythema nodosum

MTB STEP 3 (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions