Dermatology Flashcards

1
Q

6 functions of skin

A

protection, absorption, excretion, secretion, regulation, sensation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

6 morphological things to describe

A
  1. palpability (indicated by shadow)
  2. Color
  3. Shape
  4. Texture
  5. Size
  6. Location
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

circumscribed; non-palpable discoloration of the skin; less than 1 cm

A

Macule

Primary lesion

ex: freckles and rubella

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

non palpable discoloration; irregular border; greater than 1 cm

A

Patch

Primary lesion

ex: vitiligo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

well-circumscribed; solid lesion; flat topped, plateau-like; greater than 1 cm

In Epidermis

A

Plaque

Primary lesion

ex: psoriasis, discoid lupus, erythematosus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

solid elevation; less than 1 cm

A

Papule

Primary lesion

ex: acne, warts, insect bites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

solid, palpable; circumscribed lesion; larger than a papule (> 1 cm)

smaller than a tumor; originates in dermal or subcutaneous tissue

A

Nodule

Primary lesion

ex: erythema nodosum, gouty tophi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

solid, palpable, circumscribed lesion

> 2 cm

can be above, level or beneath skin surface

A

Tumor

Primary lesion

ex: lipoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

superficial, well-circumscribed, raised, fluid-filled lesion

contains serous fluid

less than 0.5 cm

A

Vesicle

Primary lesion

ex: herpes simplex, varicella (chickenpox)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

superficial, well-circumscribed, raised, fluid filled lesion

> 0.5 cm

Epidermis

A

Bulla (blister)

Primary lesion

ex: bullous pemphigoid, pemphigus, dermatitis herpetiformis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

a vesicle filled with PURULENT fluid small, circumscribed

A

Pustule

Primary lesion

ex: acne, impetigo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

slightly raised, red, irregular, transient lesions,

secondary to edema of the skin

erythematous borders with pale centers epidermis

A

Wheal

Primary lesion

ex: urticarial (hives), allergic rxn to injections or insect bites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

flat, non-blanching, red-purple lesions; caused by a hemorrhage to the skin

2 non-palpable types

A

Purpura

Primary lesion

  1. Petechia: less than 5 mm
  2. Ecchymosis (bruise): greater than 5 mm
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

SECONDARY LESION

visible shedding of stratum corneum

epidermal origin

A

Scale

ex: often seen with psoriasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

SECONDARY LESION

slightly raised; irregular border; variable color

resulting from dried blood, serum or other exudate

epidermis origin

A

Crust

ex: scab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

SECONDARY LESION

depressed lesion; resulting from loss of epidermis due to rupture of vesicles or bullae; often caused by friction or pressure

heals WITHOUT scar confined to epidermis

A

Erosion

ex: rupture of herpes simplex blister

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

SECONDARY LESION

depressed lesion resulting from loss epidermis and part of dermis

HEALS WITH SCAR irregular size and shape

A

Ulcer

ex: decubitus ulcers, primary lesion of syphilis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

SECONDARY LESION

deep linear lesion into the dermis; wedge-shaped in epidermis with abrupt walls

can extend into dermis

A

Fissure

ex: cracks in athlete’s foot

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

SECONDARY LESION

linear superficial lesion, may be covered with dried blood due to scratching of skin

*specific to itching

A

Excoriation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

SECONDARY LESION

Thickening of epidermis, resulting in accentuation of skin lines results from chronic irritation and rubbing

A

Lichenification

ex: atopic dermatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

SECONDARY LESION

replacement of normal skin with fibrous tissue; often resulting from injury involved in deeper dermis

A

Scar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

SECONDARY LESION

thinning or depression of the skin surface due to reduction of underlying tissue depression in epidermis

A

Atrophy

ex: aging, stretch marks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

SECONDARY LESION

hardening of the skin caused by an increase in collagen, mucin, edema or cellular infiltration

A

Sclerosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

SECONDARY LESION

tissue death

A

Necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Hypertrophic scar

A

heals above layer of epidermis; confined to edges of wound

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Keloidal scar

A

scar tissue goes beyond the edges of original wound

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

darkened plug of sebum and keratin that occludes the pilosebaceous follicle

some open; some closed

A

Comedone

ex: blackhead (open)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

NODULE; encapsulated containing fluid or semi-fluid substance; fluctuant

A

Cyst

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

linear or serpinginous tunnels within the epidermis

A

Burrow

ex: scabies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

small, superficial blood vessels that become visible because they are dilated;

disappear with pressure (blanch)

A

Telangiectasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Poikiloderma

A

combination of: cutaneous pigmentation (hyper- & hypo-), atrophy, and telangiectasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Distribution

A

location on the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Configuration

A

the lesions are arranged or relate to each other

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

each lesion is easily separated from others

A

discrete configuration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

edges of the lesions blend into one another

A

Confluent configuration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Isolated/solitary configuration

A

one lesion in an area

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

lesions are discrete; multiple and distributed in no pattern

A

scattered configuration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

lesions are close together WITH normal skin between groups

A

grouped configuration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

configuration

A

linear configuration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

configuration

A

dermatomal

distributed in one spinal nerve or equivalent branch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

shape

A

annular

ring-like shape

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

shape

A

polycyclic

shape made up of tangential rings

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

shape

A

arcuate

arc/crescent-shaped

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

shape

A

serpinginous

shaped like a snake

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

shape

A

iris/targetoid

shaped like a bulls-eye

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

net-like pattern

A

reticulate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

shape

A

glaborous

shiny and smooth surface; bald

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

Atopic triad

A

asthma

allergies

atopic dermatitis (eczema)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

Instruments for Elliptical excision

A

Anesthesia, 15 blade, forceps and suture

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

Instruments for shave/biopsy excision

A

anesthesia, 11-blade/curved razor, forceps and scissors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

Instruments for punch biopsy

A

Anesthsia, punch, forceps, scissors/scalpel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

Instruments for KOH preparation

A

15-blade, glass slide, 10-20% KOH, +/- petri dish test for fungal infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

Instruments for tzanck smear

A

11 blade-, glass slide OR herpes culture swab, collecting fluid to see if multinucleated giant cells ; confirms HSV/VZV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

Wood’s light: Coral/pink

A

Erythrasma (corynebacterium)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

Wood’s light: Pale blue

A

Pseudomonas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

Wood’s light: Yellow

A

Microsporum (tinea capitis)

*Fungal infection of scalp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

Wood’s light: Green/gold

A

tinea versicolor

*Fungal infection causing HYPOpigmentation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

describe this!

Macule

Primary lesion

ex: freckles and rubella

A

circumscribed; non-palpable discoloration of the skin; less than 1 cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

describe this!

Patch

Primary lesion

ex: vitiligo

A

non palpable discoloration; irregular border; greater than 1 cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

describe this!

Plaque

Primary lesion

ex: psoriasis, discoid lupus, erythematosus

A

well-circumscribed; solid lesion; flat topped, plateau-like; greater than 1 cm

In Epidermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

describe this!

Papule

Primary lesion

ex: acne, warts, insect bites

A

solid elevation; less than 1 cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
62
Q

describe this!

Nodule

Primary lesion

ex: erythema nodosum, gouty tophi

A

solid, palpable; circumscribed lesion; larger than a papule (> 1 cm)

smaller than a tumor; originates in dermal or subcutaneous tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
63
Q

describe this!

Tumor

Primary lesion

ex: lipoma

A

solid, palpable, circumscribed lesion

> 2 cm

can be above, level or beneath skin surface

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
64
Q

describe this!

Vesicle

Primary lesion

ex: herpes simplex, varicella (chickenpox)

A

superficial, well-circumscribed, raised, fluid-filled lesion

contains serous fluid

less than 0.5 cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
65
Q

describe this!

Bulla (blister)

Primary lesion

ex: bullous pemphigoid, pemphigus, dermatitis herpetiformis

A

superficial, well-circumscribed, raised, fluid filled lesion

> 0.5 cm

Epidermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
66
Q

describe this!

Pustule

Primary lesion

ex: acne, impetigo

A

a vesicle filled with PURULENT fluid small, circumscribed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
67
Q

describe this!

Wheal

Primary lesion

ex: urticarial (hives), allergic rxn to injections or insect bites

A

slightly raised, red, irregular, transient lesions,

secondary to edema of the skin

erythematous borders with pale centers epidermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
68
Q

describe this!

Purpura

Primary lesion

  1. Petechia: less than 5 mm
  2. Ecchymosis (bruise): greater than 5 mm
A

flat, non-blanching, red-purple lesions; caused by a hemorrhage to the skin

2 non-palpable types

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
69
Q

describe this!

Scale

ex: often seen with psoriasis

A

SECONDARY LESION

visible shedding of stratum corneum

epidermal origin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
70
Q

describe this!

Crust

ex: scab

A

SECONDARY LESION

slightly raised; irregular border; variable color

resulting from dried blood, serum or other exudate

epidermis origin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
71
Q

describe this!

Erosion

ex: rupture of herpes simplex blister

A

SECONDARY LESION

depressed lesion; resulting from loss of epidermis due to rupture of vesicles or bullae; often caused by friction or pressure

heals WITHOUT scar confined to epidermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
72
Q

describe this!

Ulcer

ex: decubitus ulcers, primary lesion of syphilis

A

SECONDARY LESION

depressed lesion resulting from loss epidermis and part of dermis

HEALS WITH SCAR irregular size and shape

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
73
Q

describe this!

Fissure

ex: cracks in athlete’s foot

A

SECONDARY LESION

deep linear lesion into the dermis; wedge-shaped in epidermis with abrupt walls

can extend into dermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
74
Q

describe this!

Excoriation

A

SECONDARY LESION

linear superficial lesion, may be covered with dried blood due to scratching of skin

*specific to itching

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
75
Q

describe this!

Lichenification

ex: atopic dermatitis

A

SECONDARY LESION

Thickening of epidermis, resulting in accentuation of skin lines results from chronic irritation and rubbing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
76
Q

describe this!

Scar

A

SECONDARY LESION

replacement of normal skin with fibrous tissue; often resulting from injury involved in deeper dermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
77
Q

describe this!

Atrophy

ex: aging, stretch marks

A

SECONDARY LESION

thinning or depression of the skin surface due to reduction of underlying tissue depression in epidermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
78
Q

describe this!

Sclerosis

A

SECONDARY LESION

hardening of the skin caused by an increase in collagen, mucin, edema or cellular infiltration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
79
Q

describe this!

Necrosis

A

SECONDARY LESION

tissue death

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
80
Q

describe this!

heals above layer of epidermis; confined to edges of wound

A

Hypertrophic scar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
81
Q

describe this!

scar tissue goes beyond the edges of original wound

A

Keloidal scar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
82
Q

describe this!

Comedone

ex: blackhead (open)

A

darkened plug of sebum and keratin that occludes the pilosebaceous follicle

some open; some closed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
83
Q

describe this!

Cyst

A

NODULE; encapsulated containing fluid or semi-fluid substance; fluctuant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
84
Q

describe this!

Burrow

ex: scabies

A

linear or serpinginous tunnels within the epidermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
85
Q

describe this!

Telangiectasia

A

small, superficial blood vessels that become visible because they are dilated;

disappear with pressure (blanch)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
86
Q

Location, incidence, treatment, Ddx

A

Acrochordon (skin tag)

Commonly found in skin folds

Females > males

Treated: snip excision & reassurance; few need biopsy

Ddx: wart & nevus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
87
Q

Location, incidence, treatment

A

Cafe au’Lait Spot

Usually inherited

6+ may indicate neurofibromatosis type 1

No treatment required

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
88
Q

Description, location, treatment, Ddx

MOST COMMON VASCULAR GROWTH ON SKIN

A

Cherry Angioma

Round-dome shape, slightly raised, red/purple

Mostly on trunk

Treatment: reassurance or cosmetic removal via cauterization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
89
Q

Description, incidence,location, treatment, Ddx

A

Cutaneous horm

Skin colored, horny growth

Can arise from benign, pre-CA, malignant lesions

mostly on face/scalp

Treatment: excisional biopsy; MUST INCLUDE BASE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
90
Q

Description, incidence, location, treatment, Ddx

A

Dermatofibroma

Firm, dense, dermal papule or nodule; 0.5-1 cm

Female > male

Lower extremities or UE above elbow

DIMPLE SIGN

Treatment: reassurance; eliptical excision; excisional biopsy if > 2cm

Ddx: amelanotic melanoma, neurofibroma, DFSP

91
Q

Description, treatment, Ddx

A

Epidermal (Inclusion) Cyst

Benign, firm, mobile nodule filled w/ keratin; central plug; usually asymptomatic; grow slowly and persist indefinitely

Treatment: reassurance; drain content; excision -must remove wall

92
Q

Description, incidence, location, treatment, Ddx

* Most common tumor of infancy

A

Infantile “strawberry” hemangioma

Red/purple benign vascular neoplasm ; occcurs during first year and involutes around 6

Usually head/neck

Treated if interferes with function/development

93
Q

Port Wine Stain “Nevus Flammeus”

Description, location, Associations

A

Occurs during fetal development; begins as red/pink lesion; becomes blue/purple with age/ nodules may develop in adulthood; does not involute

Mostly on head/neck

Associations: Sturge-Weber syndrome and Klippel-Ternaunay Syndrome

94
Q
A

Nervus Simplex (Salmon’s patch)

Stork bite: nape of neck

Angel’s kiss forehead between eyebrows

Almost always fades

95
Q

Soft, dense, often compressible papule or nodule

Skin-colored to brown

A

Neurofibroma

Excision if symptomatic

Neurofibratosis if > 6 care au’lait spots

96
Q

Neurofibromatosis

A

autosomal dominant disorder

affects bone, NS, soft tissue and skin

97
Q

Pigmented, tan, dark, brown

ABCDE?

A

Nevi (Mole)

Assymetry, border, color, diameter, evolution

98
Q
A

Halo Nevus

Most common in adolescence

Surrounding hypopigmentation

99
Q
A

Dysplastic Nevus

Tan, brown, pink discoloration

Irregular borders/atypical mole

Various grades (mild, moderate, severe)

BIOPSY and total body scan annually

100
Q
A
101
Q

Usually fades during childhood

A

Mongolian Spot

Deeper in skin so it hasd a blue-ish look

2-8 cm

Commonly in sacral

102
Q

Most people have at least one in lifetime

ddx?

A

Seborrheic Keratosis

“Stuck-on” appearance; crumbles; flat or raised; 0.2-2 cm

Less common under 30

ddx: skin tags, wart, melanocytic nevus, melanoma

103
Q
A

Solar Lentigo “Sun Spots”

2-20 mm; oval often irregular macules; sharp borders

Treatment: sun avoidance; creams; chemical peels

104
Q

Ass. with sun exposure

Usually on face, lips, ears, neck, forearms

A

Venous Lake

Common, soft, compressible venous papule; blue-purple in color

BLANCHES

Reassurance and cautery if desired

105
Q
A

Actinic Keratosis

Pre Malignant SCC; face, ears, balding scalp, dorsal hands/forearms

Multiple, discrete; flat OR elevated; red pigmented skin; may feel rough like sandpaper

Treatment: topical therapy, cyrotherapy, 5-fluorouracil (5-FU) or imiquimod, laser resurfacing, chem peel

106
Q

Most common form of skin cancer

” pearly papule “; doesn’t have skin lines within it; Rolled borders; (for nodular)

“dry skin patch that doesn’t heal”; for superficial

A

Basal Cell Carcinoma

Intermittent; intense sun exposre

Face, scalp, ears, neck; RARE ON DORSAL HANDS

Slow growing

SHAVE BIOPSY usually is sufficient

107
Q

Chronic, long term sun exposure (not intermittent)

Red base with hyperkeratoic white adherent scale; over times becomes nodular and ulcerated

A

Squamous Cell Carcinoma

Frequently develop on site of AK

Face,scalp, neck, dorsal hands

Faster growing

Excision with borders; DO LYMPH EXAM

108
Q

Used to be pseudomalignant, but now “malignant”

Rare before age 40; peaks 50-59

Solitary nodule; central keratotic plug; often tender

A

Keratoacanthoma (SCC, “KA” Type)

Rapid growth over weeks to months; can resolve spontaneously OR BECOME MALIGNANT

Men: dorsal hands; Women: lower legs

Treatment: BIOPSY with DEPTH; Moh’s

109
Q
A

Melanoma

Rapid increase in deadly melanocytes

Men: upper back; Women; lower legs and upper back

Check ABCDEs

Complete excision with margin; if too large, punch biopsy (ex: lentigo maligna); send to dermapathologist; follow up by dentist/ophthalmologist

110
Q
A

Amelanomic melanoma

111
Q

Breslow thickness

A

Vertical mm of tumor to the base

112
Q
A

Hutchinson’s sign - Melanoma

113
Q
A
114
Q

Keratinization of hair follicle

A

Keratosis Pilaris

F>M

MC: posterolateral upper arms

115
Q

Keratosis pilaris treatment

A

Acne cleanser (mild) followed by exfoliant

Keratolytic (ex: 12% ammonium lactate) breaks down dead skin

116
Q
A

Xerosis “dry skin”

extensor surfaces

erythema, horizontal linear splits

117
Q

Xerosis treatment

A

Avoid triggers; use “sensitive skin stuff” ; frequent hand washing/drying = BAD

Topical therapies = WET dressings; emolients IMMEDIATELY after bathing (oils > ointments > creams > lotions)

118
Q

fine, white, adherent, polygonal scale with central tacking (“pasted on”)

A

ichthyosis vulgaris

Autosomal dominant (95% heredity)

FLEXORS; LE > UE

119
Q

ichthyosis vulgaris treatment

A

Emollient use

Lactid acid, urea, or alpha-hydroxy acids for severe scaling

AVOID DRY ENVIROMENTS

120
Q

Koebner phenomena

A

likely to get some sort of lesion on top of trauma such as a skin or a burn

121
Q
A

chronic plauqe psoriasis

SYMMETRICAL

EXTENSORS

“silvery-white scale” = always psoriasis

122
Q

Auspitz sign

A

pinpoint bleeding when scale removed

123
Q
A

guttate psoriasis

1/3 BEFORE 20 y.o.; often preceeded by strep

resolves spontaneously

SUDDEN appearance (**plaques are more gradual); TRUNK!

124
Q
A

Pustular psoriasis

small sterile pustules

on palms and soles!

Von Zumbach’s syndrome; when pustules coalesce into one big area

125
Q

interiginous areas

A

Inverse psoriasis

UNCOMMON; usually lack scales

126
Q
A

erythodermic psoriasis

entire skin surface is involved

127
Q
A

Pityriasis rosea

75% = 10-35

MC in F slightly; SEASONAL (cooler months)

Herald patch: initial primary plaque; then generalized rash 1-2 weeks later; SYMMETRICAL; usually trunk

“Christmas tree distribution”; “Collarette scale”

128
Q

5 P’s: Pruritic (80%); Planar (flat-topped); Polyangular (not round); Purple; Papules

A

Lichen planus

F > M; rare in kids

*may be associated with chronic active Hep C

Wickham striae: “net-like”

Papular (localized) pattern = MC (then hypertrophic)

129
Q

Mucosal Lichen Planus

A

in oral mucosa

F>M ; onset > 60 y.o.

EROSIVE FORM: ~3% can become SCC

130
Q

“Tenting” nail

A

LIchen planus nail disease

131
Q

Lichen planus treatment

A

REFER TO DERM

Topical corticosteroids (Class I-II) for localized

Intralesional corticosteroids for hypertrophic pattern

Oral ‘mouthwash’ for mucosal

132
Q

smooth; “non-scaling”

Localized = MC

Generalized

A

Granuloma Anulare

2F: M ; dorsal hands; extensors

duration = weeks to decades; spontenous involution

central depression; arcuate/annular plaques

*Associated with diabetes

133
Q

H1 Receptors

A

Triple response of lewis: Vasodilation (erythema); axon reflex (itchiness); and wheal

134
Q

H2 receptors

A

vasodilation; increased gastric secretion (nausea)

135
Q
A

Urticaria

sudden onset; each lesion lasts

can be acute ( 6 weeks)

TREAT WITH ANTIHISTAMINES initially

136
Q

5 “I”s with urticaria

A

Infections, ingestants, inhalants, injectants, internal disease

137
Q

1st generation antihistamine

A

SEDATING

hydroxyzine (atarax)

diphenhydramine (benadryl)

138
Q

2nd generation antihistamine

A

LOW SEDATING

fexofenadine (allegra)

cetirizine (zyrtec)

loratadine (claratin)

139
Q

“non-pitted swelling”

A

angioedema

F>M; needs to be dealt with immediately

140
Q

Angioedema treatment

A

severe: epinephrine and antihistamines (maybe IV)

always refer to derm/allergist

ID bracelets; epi-pen

if HAE: replacement with C1 inhibitor concentrate; fresh frozen plasma

141
Q

Erythema Multiforme etiology and causes

A

M > F

20-40; 20 % adolescents

142
Q

Erythema multiforme clinical features

A

prodrome: malaise, fever, itching, burning, cough

primary lesion small red macule or papule with central papule that flattens and clears

TARGETOID LESION; PALMS / SOLES

143
Q

lesions start as poorly defined, red, firm , tender subcutaneous nodules; 2-6 cm; fade over 1-3 weeks

similar to bruise; do not scar

A

Erythema nodosum

5F : 1 M; extensor surcaces; BILATERAL

MC cause = strep

144
Q
A
145
Q

Tissue involved and etiology?

A

Cellulitis

dermis AND subcutaneous tissue

streptococci and staphylococcus aureus

146
Q

Major clinical features?

A

irregular, ILL-DEFINED MARGINS

unilateral; generally lower extremity

147
Q

treatment?

A

Antibiotics PO ; (IV if very ill)

Wet dressings, rest and elevation

148
Q

definition, etiology?

A

Erysipelas

“superficial cellulitis” - infection of upper dermis

Etiology: ONLY streptococcus (pyogenes)

149
Q

Major clinical features?

A

(erysipylas)

peau d’ orange appearance

UNILATERAL; raised

sharp elevated margins

150
Q

treatment?

A

(erysipylas)

antibiotics PO

(bacterial infection)

151
Q

etiology

A

(Impetigo)

staphylococcus aureus and streptococcus

VERY CONTAGIOUS

152
Q

major clinical features?

A

Impetigo

“honey colored crust” ; stuck on appearance

putsule/vesicles with yellow purulent fluid

153
Q

Treatment?

(local, widespread & recurrent)

A

(impetigo)

Local: vinegar/bleach wet dressings; topical cream (mupirocin) ; antibacterial soap

Widespread: antibiotics PO

Recurrent: swab for colonization of strep; nasal/fingernail ointment reginen

154
Q

TSS:defintion, etiology

A

(Toxic Shock Syndrome)

“emergency toxin-mediated bacterial infection”

staphylococcal and streptococcal

FEMALE > MALE

155
Q

TSS: major clinical features?

treatment?

A

(Toxic Shock Syndrome)

sudden onset of fever; STRAWBERRY TONGUE; hypotension; diffuse macular rash

REMOVE FB; early IV antibiotics

156
Q

Exanthems

A

term used for a generalized rash; (most commonly by a virus)

accompanied by systemic systems (fever, malaise, headach)

Reaction to toxin from organism; damage to the skin by the organism; OR immune response

157
Q

definition? etiology? predisposing factors?

A

Erythema infectiosum

“5ths disease” ; slapped-cheek ; childhood

Parvovirus B19

Spread via droplets/blood; late winter-early spring

158
Q

clinical presentation

course?

A

(Erythema infectiosum)

~2 days prior ; prodrome

Rash = ‘slapped-cheek’ then lacy reticular rash

Incubates 4-14 days; prodrome; 1-4 days ‘slapped cheeks’ ; 1-6 weeks extremities/trunk rash ; 1-3 possible recurrence

159
Q

treatment?

A

(Erythema infectiosum)

symptomatic/supportive

avoid heat, sun, stress

160
Q

Etiology? Predisposing conditions?

A

Hand, foot, and mouth disease

Etiology: Coxsackie A16 virus; Enterovirus 71

Conditions: seasonal (late summer/autumn) ; household contacts ; children

161
Q

clinical features?

A

(hand, foot and mouth disease) CONTAGIOUS

nose/throat discharge; small vesicles initially form in mouth (appear as chancre sores)

ovals/square, YELLOW, vesicles appear on hands, feet, buttocks

vesicles –> bulla –> ulcers (if blisters open)

lasts 7-10 days

162
Q

treatment?

A

(hand, foot and mouth disease)

Symptomatic ; isolate children 3-7 days

163
Q

etiology? predisposing?

A

(herpes simplex)

often involves mucous membrane

HSV 1: oral ; HSV 2: genital

Conditions: direct contact; droplet infection; open skin

164
Q

Herpes primary infection

A

grouped vesicles; eroding to crusts

(possible prodrome)

NUMEROUS, scattered or soliatry

resolve within 2-6 weeks; WITHOUT scarring

can be sympomatic or PAINFUl

lies dorman in dorsal root ganglia

165
Q

Herpes simplex secondary infection

A

less significant; shorter period

travels through peripheral nerves

PREDISPOSE BY: menses, fatigue, stress, trauma to area , infections

166
Q

diagnosis?

Treatment?

A

(herpes simplex)

Presentation, PCR, culture, serum assay OR tzank smear

Treat symtomatically; topical or PO antivirals

*best to start within 24 hours

167
Q

definition/etiology?

A

(Varicella) “Chicken pox” ; HIGHLY contagious ; lifelong immunity

Varicella zoster virus (VSV) aka: human herpesvirus type 3

168
Q

clinical features? course?

A

(Varicella)

14-16 day incubation after exposure; 1-2 prodrome

VARIED STAGES at same time; macules to crusts; become vesicles; SURROUNDING ERYTHEMA

* contagious 2 days before rash appears until ALL lesions are crusted

169
Q

diagnosis?

treatment?

complications?

A

(Varicella)

Clinical presentation, PCR, culture, tzank smear

symtomatic treatment; antiviral agents

*SCRATCHING can cause secondary infections; can spread in utero during pregnancy

170
Q

definition? etiology?

A

(herpes zoster ; shingles)

UNILATERAL localized infection ; usually involving a SINGLE DERMATOME

Reactivation of varicella-zoster virus

171
Q

clinical features?

A

(herpes zoster ; shingles )

3-5 days of localizes symptoms (PAIN, discomfort, itchy)

Red macule rapidly becomes a papule then a vesicle; surrounded by erythema

Vesicles group over 2-3 weeks; become pustular; then scab over; WHITE SCAR

172
Q

diagnosis? treatments? common complications?

A

(herpes zoster ; shingles )

clinical presentation, PCR, tzank smear

treatment: antiviral agents; rest; topical analgesics, narcotics steroids

AV agents prevent post-herpetic neuralgia

HZ opthalmicus : can cause blindness; dentrite appearance in eye

173
Q
A

HZ opthalmicus

*distinct on central axis; vesicles on the side or tip of nose

174
Q

definition? etiology? predisposing?

A

(Molluscum contagiosum)

self-limiting mucocutaneous viral infection; can last months to years

Poxvirus

Swimming pools; communal bathing

175
Q

clinical features?

A

(Molluscum contagiosum)

skin-colored papule ; dome shaped with central punctum (umbilicated)

white molloscum bodies at center of papules

176
Q

diagnosis? treatment?

A

(Molluscum contagiosum)

presentation, biopsy, microscopic eval of core

Treat: supportive; topical treatment (tretinoin, aldara, cantharidin, salicylic acid); NO COMMUNAL BATHING

Remove if in genital area***

177
Q

etiology; predisposing?

A

( Measles (rubeola) )

Parmyxovirus group

Predisposing: densley populated regions; lack of immunizations

178
Q

clincial features?

three C’s?!

A

( Measles (rubeola) )

10-12 day incubation; HIGH FEVER

3 C’s: cough, coryza (runny nose), conjuctivitis

Koplick spots on buccal mucosa (blue-white spots on a red base

Exanmthem: “Morbilliform rash” starts on face, hairline & behind ears; MOVES DOWNWARD; clears in 3-4 days; leaves coppery stain

179
Q

diagnosis? treament?

A

( Measles (rubeola) )

Antibody titers; presentation; QUARANTINE if positive

Treat: symptomatic; antibiotics with secondary infections

180
Q

definition? etiology?

A

(Rubella - German measles)

common viral infection affecting skin, lymph nodes and joints

Etiology: togavirus

181
Q

clinical features?

A

(Rubella - German measles)

(Incubation: 14-21 days)

prodrome -malaise, tender lymphadenophathy, fever

2-3 mm pink macules appear with prodrome; begin on face/scalp & move downward

Become papular and then desquamate - fade within 3 days

Forchheimer spots: red petechiae on soft palate

182
Q

diagnosis? treatment?

A

(Rubella - German measles)

serology; presentation

Treat symptomatically

*THREAT TO UNBORN CHILD

183
Q

definition; etiology; predisposing

A

(Roseola infantum) - “Childhood exanthem”

sudden rash after fever; “6th disease”

Etiology: HHV-6 or HHV-7

6-35 mo. ; spring time ; trans by droplets

184
Q

clinical features?

A

(Roseola infantum)

High fever each night x3 (goes away in morning)

After 3rd night fever breaks; subtle pink maculopapular rash; mostly NECK AND TRUNK

otherwise asymtomatic

185
Q

diagnosis; treatment

A

(Roseola infantum)

clinical presentation, cultures, serology

treating: supportive

186
Q

etiology; predisposing

A

(warts)

Human papilloma virus

Predispos: localized trauma, immunosuppresion, communal bathing

MOST COMMON ON HANDS

187
Q

clinical features; 4 types;

A

(warts)

common, plantar, mosaic, planar (flat)

Confined to the epidermis; interrupt normal skin lines

188
Q

diagnosis; treatment; prevention

A

(warts)

clinical presentation (disrupts skin lines; thrombosed capillaries (little black dots))

Treat: spontaneously involute OR physical, chemical, immunotherapy

Prevent: dry, clean surfaces; sandals in common areas

189
Q

Candidiasis description

A

yeast type of infection

candida albicans; causes majority of fungal

affects skin and MUCOUS membranes

lives within normal fluora of the mouth, vaginal tract and gut

EXTREME AGES

190
Q

candidiasis clinical presentation

A

superficial infection; outer layers of ep

PRIMARY LESION = erythematous papule or pustule

Scaling, advancing borders - stops when it reaches dry skin

Satellite lesions

191
Q

candidiasis diagnosis

A

clinical presentation; KOH

192
Q

definition; risk factors; clinical presentation

A

(Candida balantis)

inflammation of the glans penis

Risks: uncircumcised males; diabetics/immunosupressed

Tenderness/pain; inability to retract foreskin; pin-point papules

193
Q

diagnosis; treatment; prevention

A

(Candida balantis)

clinical presentation, location, KOH, cultures

topical antifungal; FINISH ALL; retract gently/wash

Prevent: keep areas dry, cleanliness, powders

194
Q

definition: predisposing; common sites

A

(candida intertrigo)

superficial yeast infection of intertriginous areas

obesity, diabetes, pendulous breasts, humid weather

sites: groin/gluteal folds/ under breasts/ allilae

195
Q

clinical presentation

A

(Candida intertrigo)

erythematous macerated folds; satellite papules/pustules

Glistening plaques

SYMMETRIC

196
Q

diagnosis; treatment; prevent

A

(Candida intertrigo)

clinical presentation; KOH; culture

treat: topical antifungal, vinegar wet dressings, burrows solution, DRY

Prevent: powders, ointments, weight loss

197
Q

definition; predisposing

A

(oral candidiasis (thrush) )

yeast infection of the mucous membranes of the mouth (palata, esophagus, pharynx)

neonate, diabetes, antibiotic use, extreme ages

198
Q

clinical presentation

A

oral candidiasis (thrush)

burning/pain with spicy food; diminished taste

creamy white exudates/ plaque like lesions of mucus membranes

199
Q

diagnosis; treatment

A

oral candidiasis (thrush)

presentation; KOH

Treat: topical antifungal (nystatin) - tablet OR gentian violet (stain)

200
Q

definition; predisposing

A

angular chelitis

inflammation of the angles of hte mouth; secondary to saliva maceration

eldery, poor fitting dentures, ACCUTANE use

201
Q

clinical presentation; diagnosis; treatment

A

angular chelitis

sore, raw, macerated at the angles of the mouth; erythematous

presentation; culture

treat: aquaphor; topical anti-fungal; topical steroid sparingly

202
Q

definition; etiology

A

(tinea/ptiyriasis versicolor)

chronic asymptomatic superficial fungal infection of the torso

Malassezia furfur, M. globosa

May or may not be contagious

203
Q

predisposing; clinical presentation

A

tinea/ptiyriasis versicolor

factors: oily skin, heat, moisture warm climates

fungus gets into melanin and causes them not to tan as much; asymptomatic

sharply marginated, fawn colored/brown/pink oval macule with fine powdery scale

204
Q

diagnosis ; treatment

A

tinea/ptiyriasis versicolor

KOH; wood’s lamp (irregular pale yellow to white or green fluorescence)

treat: topical - selenium sulfide (selsum blue shampoo); oral antifungal - hypopigmented areas may not disappear immediately

205
Q

tinea

A

Dermatophyte

Group of fungi capable of infecting skin, hair and nails

Most common of all mucocutaneous infections*

Predisposition: wrestlers, day cares, pets, etc

206
Q

definition; etiology

A

tinea capitis

Invasion of the stratum corneum and the hair shaft with fungal hyphae

etiology: 90% trichophyton

207
Q

Clinical - 4 types

A

tinea capitis

1: inflammatory
2: seborrheic: (patchy fine adherent scales; MOST COMMON
3: non-inflammatory : black dots, alopesia
4: pustular: pustules; NO SCALING OR ALOPESIA

208
Q

diagnosis; treatment

A

tinea capitis

KOH; woods lamp (BRIGHT GREEN); culture

treat: both oral and topical preps (griseofulvin and antifungal shampoo)

treat pets too!

209
Q

definition; clinical presentation; diagnosis

A

inflammatory tinea capitis

boggy tender areas of alopecia; scarring; painful

KOH - REFER!

210
Q

definition; predisposing; etiology

A

tinea corporis - “ring worm”

dermatophyte of the trunk

warm climates, close contact (wrestlers)

T. rubrum; M. canis; T tonsurans

211
Q

clinical presentation; diagnosis; treat

A

tinea corporis - “ring worm”

papules/macules; raised red border with central clearing or brownish discoloration

pustules, vesicles, bullous

asymptomatic or itchy

Clinical presentation; KOH; culture

treat: topical antifungal; extensive use oral

212
Q

definition; etiology

A

tinea cruris “jock itch”

tinea of the groin; almost exclusively in post-pubertal boys (M>F)

T. rubrum; T. mentagrophytes

213
Q

clinical presentation; diagnosis

A

tinea cruris “jock itch”

itching (increases with moisture); usually BILATERAL; can migrate to buttocks

plaques with scale; spares penis/scrotum

clinical presentation; KOH; culture

214
Q

definition; predisposing

A

tinea manus

“tinea of the hand”

Pre: tinea pedis/cruris

*UNILATERAL commonly

215
Q

clinical presentation; diagnosis

A

tinea manus

scaling/hyperkeratosis; palmar creases, fissures pronounced

progresses slowly

papules, vesicles, bullae

Clinical presentation; KOH

216
Q

treatment

A

tinea manus

topical antifungals -often fails

oral often used

KEEP HANDS DRY; can recur if nails are not clear

217
Q

definition; etiology; predisposing

A

tinea pedis “ athletes foot “

DERMATOPHYTS: T. rubrum, T. mentagrophytes, E. floccosum

Pre: dark, warm, moist enviroment; locker rooms

218
Q

clinical presentation; treatment; diagnosis

A

tinea pedis “ athletes foot “

lessions may be annular; between digits; moccasin distribution

scaling, macerated, erythema, bulla formation

Clinical; KOH; culture; NEG wood’s lamp

Treat: PO or topical antifungal; change socks freq. dry well

219
Q

describe this!

heals above layer of epidermis; confined to edges of wound

A

Hypertrophic scar

219
Q

describe this!

scar tissue goes beyond the edges of original wound

A

Keloidal scar

219
Q

describe this!

Comedone

ex: blackhead (open)

A

darkened plug of sebum and keratin that occludes the pilosebaceous follicle

some open; some closed

219
Q

describe this!

Cyst

A

NODULE; encapsulated containing fluid or semi-fluid substance; fluctuant

219
Q

describe this!

Burrow

ex: scabies

A

linear or serpinginous tunnels within the epidermis

219
Q

describe this!

Telangiectasia

A

small, superficial blood vessels that become visible because they are dilated;

disappear with pressure (blanch)