Dermatology Flashcards

1
Q

Treatment for acitinic keratoses

A

FLUOROURACIL CREAM: 2 TO 3 WEEKS +/- TOPICAL HYDROCORTISONE

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2
Q

Imiquimod topical is used for

A

Acitinic keratoses

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3
Q

Drugs that causes non scarring alopecia

A
  1. Carbimazole
  2. Heparin
  3. Ocps
  4. Colchicine
  5. Cytotoxic Drugs
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4
Q

Which nutrient deficiency is related to alopecia?

A

Iron and Zinc

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5
Q
A
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6
Q

Sub epidermal blistering of the skin in which disease?

A

Bullous Pemphigoid

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7
Q

Bullous Pemphigoid has antibodies against

A

Hemidesmosomal Proteins BP180 AND BP230

Ab type: IgG and C3 at dermoepidermal junction

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8
Q

Do blisters heal with or without scarring in bullous Pemphigoid

A

Without scarring

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9
Q

Bullous Pemphigoid peculiar characteristics that differ it from pemphigus:

A

No mucosal involvement

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10
Q

Mainstay Of treatmenf for bullous Pemphigoid

A

Oral corticosteroids

Referral case from GP for biospy

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11
Q
A
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12
Q

Dermatomyositis is associated with which malignancies

A

Ovarian, breast and lung cancer

Screening is usually done!!

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13
Q

Characteristics skin lesions in dermatomyositis

A
  1. Heliotrope Rash: bilateral lilac discolouration of the eyelids, esp upper and swelling
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14
Q

What is shawl sign and present in which disease?

A

Macular rash over back and shoulder, chest and neck

Dermatomyositis

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15
Q

What are gottron papules? And in which disease?

A

Red / purple papules over the extensor surfaces of fingers

Dermatomyositis

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16
Q

Dermatomyositis is characterised by skin lesions and

A

Symmetrical proximal muscle weakness

17
Q

The majority of patients (80%) with dermatomyositis are

A

ANA POSITIVE

18
Q

Dry and scaly hands with linear cracks on the palmar and lateral aspects of the fingers

A

Mechanic hands seen in dermatomyositis

19
Q

Nail fold characteristic change in dermatomyositis

A

Capillary dilatation

20
Q

What is the first symptom of acne rosacea?

21
Q

Acne rosacea affects which part?

A

Central face: nose, cheeks and forehead

22
Q

Thickened skin around nose and enlarged sebaceous gland

A

Rhinophyma in acne rosacea

Red colored skin; prominent blood vessels

23
Q

Telengiectasia are common in

A

Acne rosacea

24
Q

Inflammatory papules and pustules, including telengiectesia, flushing, and ocular involvement, are major criteria for?

A

Acne rosacea

25
Patients with predominant flushing but limited telengiectasia in acne rosacea are treated with
TOPICAL BRIMONIDINE GEL
26
Resistant or severe acne rosacea is treated with
Oral oxytetracycline-----> doxycycline
27
Abx for limited number of papules and pustules without plaques in acne rosacea
Topical metronidazole
28
Hematopoiesis is depressed by with medication
Trimethoprim
29
Increased risk of drug induced lupus and hyperpigmentation is associated with which medication?
Oral Minocycline
30
The most common side effect of isotretinoin
Dry skin, eyes, and lips/mouth
31
Side effect of erythromycin
Affect hepatic metabolism of other medications
32
Acrodermatitis Enteropathica is associated with................ deficiency
ZINC
33
Triad related to acrodermatitis enteropathica
1. Peri acral ( peripheral: toes and fingers ) and periorificial, perianal 2. Diarrhea 3. Alopecia
34
35
Defect in acrodermatitis
Intestinal zinc absorption : Autosomal recessive pattern
36
Red crusted lesions with peri acral and periorificial distribution is seen in
Acrodermatitis enteropathica
37
Treatment for acrodermatitis
High dose elemental zinc at 3mg/kg/day: 50mg elemental zinc in 220mg of zinc sulphate
38